BIOLOGICAL APPROACH TO EXPLAINING OCD Flashcards

(26 cards)

1
Q

how many explanations are there for OCD in the biological approach?

A

2

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2
Q

what are the two explanations for OCD?

A

genetic

neural

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3
Q

what are candidate genes in OCD?

A

a gene of interest when looking a particular behaviours/characteristics that could be inherited

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4
Q

what are family studies?

A

family studies are when you look at similarities within families for example if one relative has OCD what at the chances of others

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5
Q

what are chromosomes?

A

23 pairs of chromosomes, 46 in total

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6
Q

what are genes?

A

information about a part of you

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7
Q

what is DNA?

A

a chemical structure

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8
Q

what are concordance rates?

A

the rate of similarity e.g. in twin studies

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9
Q

what are two candidate genes that can lead to the inheritance of OCD?

A

COMT

SERT

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10
Q

what does the COMT gene regulate?

A

levels of dopamine

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11
Q

in OCD, are the levels of dopamine increased or decreased?

A

they are increased

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12
Q

who supports that the COMT gene can lead to higher levels of dopamine?

A

Tukel who says that a variation/mutation in the COMT gene can lower activity and increase levels of dopamine

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13
Q

what does the SERT gene regulate?

A

the levels of serotonin

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14
Q

are levels of seratonin increase or decreased on OCD?

A

decreased

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15
Q

who has research to support the SERT gene leading to the inheritance of OCD?

A

Ozaki found that a mutation of SERT gene in unrelated families with 6/7 members with OCD had lower levels of seratonin

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16
Q

OCD is…

17
Q

what does polygenic mean?

A

means many genes

18
Q

who found that there may be over 230 genes involved in the inheritance of OCD?

19
Q

what are neural explanations for OCD?

A

serotonin

decision making system

20
Q

how does the neural explanation describe serotonin?

A

low levels of serotonin lower mood

21
Q

what are the neurotransmitters responsible for?

A

responsible for relaying information from one neuron to another

22
Q

what occurs if there are lower levels of serotonin than normal?

A

no transmission of mood relevant information

23
Q

what is impaired in the frontal lobes?

A

decision making systems

24
Q

what are the frontal lobes responsible for?

A

logical thinking and decision making

25
what part of the brain is dysfunctional in OCD according to the neural explanation?
the paragippocampal gyrus
26
what is the parahippocampal gyrus responsible for?
processing unpleasant emotions