block 5 lecture 11 spinal reflexes Flashcards

1
Q

what are the three main types of movement?

A

reflex, rhythmic and voluntary

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2
Q

what does the dorsal side of the spinal cord receive input from?

A

the senses

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3
Q

how do the sensory nerves enter the spinal cord?

A

dorsal roots

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4
Q

where does the spinal cord get bigger?

A

cervical and lumbar enlargements

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5
Q

where is the cervical enlargement?

A

C3-T1

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6
Q

where is the lumber enlargement?

A

L1-S1

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7
Q

how are the motor neurons in the grey matter of the spinal cord organised?

A

somatotopically - in relation to the body

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8
Q

what controls the axial parts of the body?

A

medial neurons

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9
Q

what do lateral neurons control?

A

distal parts of the body

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10
Q

what are alpha neurons part of?

A

final common pathway

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11
Q

where do upper motor neurons remain?

A

the central nervous system

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12
Q

what do lower motor neurons do?

A

send axons directly to muscles

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13
Q

what are the head muscles controlled by?

A

motor neurons in the brain stem

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14
Q

where are the muscles of the body motor neurons?

A

spinal cord

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15
Q

where are alpha neurons found in the spinal cord?

A

ventral horn

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16
Q

where do the alpha motor axons go?

A

the axons pass through the ventral root and through spinal nerve and terminate at neuromuscular juntsion

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17
Q

why are the ALPHA motor neurons?

A

thickest neurons meaning very rapid conduction

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18
Q

what is the main neurotransmitter in muscle control?

A

acetylecholine

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19
Q

what does acetylecholine do?

A

initiate muscle contraction

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20
Q

what does myelination allow?

A

saltatory conduction

21
Q

where is sensory input gathered from?

A

cerebral cortex, spinal interneurons, muscle spindle and skin

22
Q

what is the most common motor neuron disease?

A

ALS - amyotropic lateral sclerosis

23
Q

what happens in ALS?

A

progressive degeneration of the alpha motor neurons

24
Q

what are the symptoms of ALS?

A

muscle weakness, atrophy, difficulty breathing and swallowing and affect on cognitive function

25
in ALS why are the eyes the last to be effected?
highly vasculated and highly innervated
26
what is a possible cause of ALS?
too much glutamate in the brain
27
what blocks glutamatergic neurotransmission?
riluzole
28
does the sensory neurons always synapse with the interneurons in the reflex arc pathway?
may synapse directly with motor neuron
29
where are muscle spindle in relation to normal muscle?
located parallel to muscle fibers
30
what are normal muscle fibers called?
extrafusal muscle fibers
31
what are the spindle muscle fibers called?
intrafusal
32
how does the neuron carry information to the spinal cord?
1a afferent neuron wraps around the muscle spindle and goes into the dorsal root of the spinal cord
33
what neuron innervate intrafusal muscle fibers?
gamma motor neurons
34
what can muscle spindle detect?
changes on the muscle
35
what is the stretch reflex?
myotactic reflex,
36
what is the patella tendon tap?
this is a stretch reflex
37
what happens when the tendon is tapped?
the quadriceps are stretched, 1a muscle spindle is activated, impulses travel to the spinal cord and activate motor neurons which release acetylecholine and contract the quads
38
what is the stretch reflex reciprocal inhibition?
while stretch reflex is occurring, collateral branch send information to inhibitory interneruon to inhibit antagonistic muscle
39
what does the mono synaptic stretch reflex control?
contracts agonist muscle
40
what dose the reciprocal inhibition control?
inhibits antagonistic muscle
41
in the inverse stretch reflex pathway what is the sensory organ?
golgi tendon
42
where is the golgi tendon?
between tendon and muscle fibers, runs in series with the extrafusal fibers
43
what happens in the inverse stretch reflex pathway?
it send out 1b afferent which synapses with interneruon in the spinal cord which inhibits the alpha motor neuron to stop muscle contracting
44
what is the golgi tendon innervated by?
1b
45
what is the threshold of the golgi tendon like?
very high - you need alot of contraction to activate
46
what is the golgi tendon made up of?
collagen fibers
47
how are the 1b activated?
force acts on the collagen fibers in the tendons to increase tension causing compression of the fibrils which activates dendrites of the 1b afferent
48
what happens in the flexor withdrawl reflex?
nociceptors are activated, impulses are sent along afferent neurons.............