α-blockers Flashcards Preview

Step 1 Pharmacology > α-blockers > Flashcards

Flashcards in α-blockers Deck (7)
1

Nonselective - What are the applications of Phenoxybenzamine (irreversible)?

Pheochromocytoma (used preoperatively) to prevent catecholamine (hypertensive) crisis

2

Nonselective - What toxicity does Phenoxybanzamine (irreversible) have?

Orthostatic hypotension; reflex tachycardia

3

Nonselective - What are the applications of Phentolamine (reversible)?

Give to patients on MAO inhibitors who eat tyramine-containing foods

4

α1 selective (-osin) - What are the applications of Prazosin, Terazosin, Doxazosin, Tamsulosin?

Urinary symptoms of BPH; PTSD (prazosin); hypertension (except tamsulosin)

5

α1 selective (-osin) - What toxicites do Prazosin, Terazosin, Doxazosin, Tamsulosin have?

1st-dose orthostatic hypotension, dizziness, and headache

6

α2 selective - What is the application of Mirtazapine?

Depression

7

α2 selective - What toxicities do Mirtazapine have?

Sedation, ↑ serum cholesterol, ↑ appetite