Blood

Question 1

3: Megakaryocytes

Answer 1

Cells with multiple copies of DNA

Question 2

3: Thrombopoietin

Answer 2

Stimulates megakaryocytes to extend arms through bone marrow

Question 3

3: Where are platelets stored

Answer 3

Spleen

Question 4

3: Haemostasis

Answer 4

• arrest of bleeding from broken blood vessel
• Vascular spasm
• Formation of platelet pug
• Blood coagulation

Question 5

3: Platelet plug formation - how do platelets stick to each other

Answer 5

Using von wilebrands factor

Question 6

3: Prostacyclin

Answer 6

Inhibits platelet aggregation

Question 7

3: What supports platelet plug

Answer 7

Blood clotting

Question 8

3: Pathways stimulating thrombin activity - intrinsic

Answer 8

Initial stimulus exposed collagen

Question 9

3: Pathways stimulating thrombin activity - extrinsic

Answer 9

Blood contact with damaged tissue which exposes tissue factor

Question 10

3: Plasmin

Answer 10

Dissolves clot

Question 11

3: haemostasis diseases

Answer 11

Haemorrhage 
Abnormal clotting (thrombosis)

Question 12

3: Thrombocytopenia

Answer 12

Low platelet count

Drug induced

Question 13

4: major sugars involved in ABO system (carbohydrates)

Answer 13

Fucose 
Galactose 
N-acetyl galactose mine 
N-acetylglucosamine 
Sialic acid

Question 14

4: ABO gene

Answer 14

A,B dominant to O

Question 15

4: What does H gene code for

Answer 15

Fucosyl transferase

Question 16

4: Blood type O

Answer 16

Some people don’t have A or B transferase and only make H substance

Question 17

4: people without A and B substances in their RBCs develop

Answer 17

antibodies against either or both

Question 18

4:agglutiantion results in

Answer 18

RBC lysis