Blood Flashcards

(63 cards)

1
Q

SPECIALIZED connective tissue consisting of cells and fluid extracellular material

A

Plasma

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2
Q

Per adult, on average liters of blood

A

5 liters

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3
Q

Formed Elements in the plasma:

A

RBC
WBC
Platelets

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4
Q

Distributing vehicle transporting oxygen, carbon dioxide, metabolites, hormones, and various substances

A

blood

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5
Q

Distribution of nutrients

A

blood

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6
Q

Collection of wastes

A

blood

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7
Q

Distribution of heat thereby leading to

A

body temperature regulation

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8
Q

Maintenance of acid-base balance

A

homeostasis

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9
Q

ANUCLEATED, with an abundance of
HEMOGLOBIN

A

erythrocytes

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10
Q

Biconcave in shape

A

erythrocytes

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11
Q

Life span erythrocytes

A

120 days

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12
Q

Senescent or worn-out RBCs are
identified and removed from the circulation

A

mainly
by
MACROPHAGES of the SPLEEN,
LIVER, and BONE MARROW

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13
Q

WBCs leave the blood and migrate to the tissues where they
become functional and perform various functions in relation to the
body’s defense system.

A

leukocytes

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14
Q

kill and phagocytose bacterial

A

neutrophils

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15
Q

kill helminthic and other parasites, modulate local inflammation

A

eosinophils

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16
Q

modulate inflammation, release histamine during allergy

A

basophils

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17
Q

effector and regulatory cells for adaptive immunity

A

lymphocytes

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18
Q

precursors of macrophages and other mononuclear phagocytic cells

A

monocytes

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19
Q

Granulocytes (3)

A

neutrophils, eosinophils, basophils

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20
Q

Agranulocytes (2)

A

lymphocyte, monocyte

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21
Q

Possess two major types of abundant cytoplasmic granules

A

granulocytes

lysosomes, azurophilic granules
specific granules: basophils, eosinophils, neutrophils

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22
Q

Multilobular (2-5 lobes linked by thin nuclear
extensions)

A

neutrophils

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23
Q

Sausage shaped nucleus “drumsticks”

A

neutrophils

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24
Q

Hypersegmented Neutrophils

A

more than 5 lobes

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25
Inactive and spherical while circulating but become amoeboid and highly active during diapedesis.
neutrophils
26
1ST TO ARRIVE AT SITES OF INFECTION
neutrophils
27
Half-life of 6-8 hours in the blood
neutrophils
28
neutrophils life span
1-4days
29
Same size as the neutrophil (but may be slightly bigger)
eosinophils
30
Nucleus is bilobed
eosinophils
31
eosinophils life span
7-14 days
32
kills parasitic worms or helminths
eosinophils specific granules
33
basophils life span
months
34
Nucleus is divided into two irregular lobes, but the large specific granules overlying the nucleus usually obscure its shape
basophils
35
Strong basophilia of the granules is due to the presence of ____ and other ____
heparin glycosaminoglycans
36
Lacks specific granules, but contains azurophilic granules
Agranulocytes
37
Nucleus is spherical or indented but not lobulated
Agranulocytes
38
Smallest leukocyte
lymphocytes
39
Spherical and compact nucleus
lymphocytes
40
Precursor of the plasma cell
lymphocytes
41
MOST NUMEROUS TYPE OF AGRANULOCYTE
lymphocytes
42
Subdivided into functional groups by distinctive surface molecules
CLUSTER OF DIFFERENTIATION or “CD Markers” lymphocytes
43
44
major classes HUMORAL IMMUNITY
b lymphocytes
45
major classes CELL MEDIATED IMMUNITY
Helper T Cells (CD4), Cytotoxic T Lymphocytes (CD8), Natural Killer (NK Cells)
46
Precursor cells of → Macrophages, Osteoclasts, Microglia
monocytes
47
Large nuclei, distinctly indented or CShaped/Kidney Shaped in appearance
monocytes
48
Enters the bloodstream and circulate 12 to 100 hours then enter the connective tissue proper where they mature to macrophages or histiocytes.
monocytes
49
Minute, non-nucleated, membrane-bound cell fragments
Platelets "THROMBOCYTES"
50
Originate by separation from ends of cytoplasmic processes extending from giant polypoid bone marrow cells called
thrombocytes (platelets) MEGAKARYOCYTES
51
platelets (thrombocytes) life span
10 days
52
Is the solvent in which formed elements are suspended and proteins and solutes are dissolved
water 92% of plasma
53
All proteins serve to buffer against pH changes
plasma proteins 7% of plasma
54
Exerts osmotic force to retain fluid within the microvasculature
albumin 58% of plasma proteins
55
Contributes to blood's viscosity Binds and transports some fatty acids, electrolytes, hormones and drugs
albumin 58% of plasma proteins
56
a-____ transport lipids and some metal ions
globulins 37% of plasma proteins
57
b- ___ transport iron ions and lipids in bloodstream
globulins 37% of plasma proteins
58
y-___ are antibodies with various immune functions
globulins 37% of plasma proteins
59
Participates in blood coagulation (clotting); precursor of fibrin
Fibrinogen 4% of plasma proteins
60
61
Consists of enzymes, proenzymes, hormones, and the complement system
regulatory proteins 1% of plasma proteins
62
Granulocytes (3)
Basophils Eosinophils Neutrophils
63
Agranulocytes (2)
Monocytes Leukocytes