BMS10 Flashcards

1
Q

Where does the apex of the heart sit?

A

5th intercostal space

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2
Q

Which valve has a different amount of cusps?

A

Mitrial has 2 and the others have 3

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3
Q

What is the auricle?

A

Outpouch of the atria

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4
Q

What are the 3 surfaces of the heart?

A

Diaphragmatic, anterior and pulmonary

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5
Q

What does the pericardium prevent?

A

Over filling of the heart

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6
Q

Where do cardiac veins drain?

A

Into the coronary sinus

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7
Q

What stops over dilation of valves?

A

The cardiac skeleton

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8
Q

Name the 3 layers of the pericardium

A

Pericardium (outer)
Visceral
Serous (inner)

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9
Q

What is the main factor in TPR?

A

Arterioles

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10
Q

Which type of circulation has lower pressure?

A

Pulmonary is lower than systemic

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11
Q

What is preload?

A

The filling of the heart

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12
Q

What is ohms law?

A

1= V / R

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13
Q

How do you calculate MAP?

A

D + (S-D)/3

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14
Q

What is darcys law?

A

That flow is proportional to resistance

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15
Q

How do calculations of series and parallel circuits differ?

A

Series you add but parallel you have to do the inverse of

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16
Q

What does plasmin do?

A

Break down clots

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17
Q

What does APC do?

A

Prevent blood from clotting by inhibiting the activation of plasminogen

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18
Q

Which blood type can accept anyone’s blood and why?

A

AB because they have no antibodies in plasma against A and or B

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19
Q

Which blood type can be given to anyone and why?

A

O as is doesn’t have any antigens able to trigger an immune response

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20
Q

What happens if you get given the wrong blood type?

A

You clot

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21
Q

What treats venous thrombosis? (2)

A

Anticoagulant

Fibrinolytics

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22
Q

Give an example of an antiplatelet

A

Aspirin

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23
Q

What do platelets also do?

A

Cause vasoconstriction

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24
Q

What does thrombin do?

A

Convert fibrinogen to fibrin to then join the platelets together

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25
What does fibrin do?
Join the platelets together
26
What cross links fibrin?
Calcium
27
What forms thrombin?
Prothrombin
28
What is an arterial thrombi?
Fat aggregation
29
What is haemophilia?
Inability to clot
30
What can activate anti-thrombin?
Antithrombin
31
What is APS?
Abnormal clotting
32
What vitamin is needed to make prothrombin?
K
33
What does NO do in thrombosis?
Inhibit platelet aggregation
34
What is metabolic hyperaemia?
Build up of metabolites due to exersize
35
How do you calculate MABP?
CO x HR
36
Where are the stretch receptors?
Aortic arch and carotid sinus
37
How does the brain stem react when the baroreceptor reflex is activated? (2)
Increase CO | Decrease CVP and TPR
38
When blood pressure changes what 4 other measurements change?
CO, SV, EDV, EDP
39
What 5 measurements contribute to BP?
SV, HR, TPR, blood volume and CVP
40
What is starlings law?
The more blood entering in diastole increasing the amount of blood leaving in systole
41
What actives baroreceptors?
When standing there is a sudden drop in CVP, EDV and SV
42
Which nervous system controls dilation etc. and why?
Sympathetic because it connects to most arterioles in the body
43
Name the branches of the nervous systems
Central & Peripheral Peripheral = Somatic & Autonomic Autonomic = Parasympathetic & Sympathetic
44
What hormones cause vasoconstriction/dilation?
Noradrenaline dilates | Adrenaline constricts
45
Which hormone decreases heart rate?
Acetylcholine
46
Which hormone increases heart rate?
Noradrenaline
47
How does ang2 affect arteries?
Constrict
48
What do mast cells do?
Make histamine to dilate and make capillaries more leaky
49
What has a higher affinity noradrenaline or adrenaline?
Noradrenaline
50
What does vasopressin do?
Constrict vessels
51
What does ANP do to vessels?
Dilate them
52
What causes angina?
Heart not receiving enough oxygen
53
What does myocardial infarction cause?
Death of heart muscle
54
What does NO do?
Relax smooth muscle to vasodilate
55
What is stenosis?
Vessels can't dilate
56
What causes oedema?
When the volume leaving capillaries is greater than the lymph can pick back up
57
Where are arteriovenous anastomoses? Describe their structure
At extremities | Wide and muscular
58
What's the primary force oncotic or hydrostatic?
Hydrostatic
59
What allows for heat loss?
Dermal venous plexus
60
Give an example of where you could find fenestrated and discontinuous endothelium?
Kidneys | Spleen and liver
61
What hormones alter heart rate? How do they do this?
Ach (increasing ion conductance) and beta blockers slow it | Noradrenaline make it faster by increasing ion conductance
62
What is preload?
Filling pressure
63
What is the primary force filling ventricles?
Elastic recoil
64
What happens after decay time?
Action potential is initiated
65
What is the haematocrit volume?
Volume of packed cells
66
What are RBC precursors?
Normoblasts then reticulocytes
67
What are platelets?
ER ejections
68
What do lymphocytes mature?
Thyroid
69
Name 2 leukocytes
Monocytes and lymphocytes
70
Describe the megakaryocyte nuclei
Single and irregular
71
What branch do neutrophils and monocytes come under?
Phagocyte
72
Describe the leukocytes nucleus?
Mono
73
Name all the granulocytes and the type of nucleus they have
Neutrophil, eosinophil, basophil | Multi lobes
74
What do albumins do?
Make things more soluble
75
What cell are mast cells related do?
Basophils
76
What encases fibres?
Fasicle
77
Where do you find myoepithelial muscle?
Glands
78
What forms when many myoblasts fuse?
Myosin
79
Which type of muscle is the only one able to respond to hormones?
Smooth
80
Is lub or dub louder?
Lub
81
What do P, T and QRS mean?
P: atrial depolarisation QRS: ventricle depolarises T: ventricle repolarises
82
What is angiogenesis?
Forms vessels from existing capillaries
83
What makes fenestrations in the capillaries?
Diaphragms cover the holes
84
What joins arteries and veins?
Arteriovenous shunts
85
Where is the sternal angle?
Rib 4 and 5
86
What does hemizygous drain into?
From the left into the azygous which is on the right
87
Where does the aorta emerge?
Behind the diaphragm at T12
88
Name the 3 branches from the aorta
Common carotid Subclavian Branchiocephalic