BMS11 Flashcards

1
Q

What is the blood vessel system called?

A

Vasa recta

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2
Q

What comes off of primary processes from the cell body?

A

Pedicles

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3
Q

What is the renal corpuscle?

A

Glomerulus, afferent and efferent arteries

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4
Q

What things can move passively into tubules?

A

Chloride, urea, potassium, hydrogen, calcium and hydrogen carbonate

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5
Q

If the afferent arteriole constricts what happens?

A

Hydrostatic pressure is lowered decreasing the glomerular filtration rate

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6
Q

What 2 things does endothelium line?

A

Lymph and blood vessels

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7
Q

Describe the tubes order (9)

A

PCT, SCT, thin loop, thing loop, thick loop, DCT, cortical CD, medullary CD and renal pelvis

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8
Q

Where is the macula densa found?

A

Lines where the DT meets the thick limb

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9
Q

Describe the bowmans wall (5)

A

Bowmans capsule, bowmans space, podocytes on the capillaries, the BM, fenestrated endothelium and then the capillary itself

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10
Q

What is the macula densa?

A

Cells that detect Na concentrations

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11
Q

Name the 2 types of nephrons

A

Cortical- short loops in the outer region

Medullary- long loops in the inner region

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12
Q

Where are mesangial cells?

A

Between capillaries in the glomerulus

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13
Q

What nervous system controls mesangial cells?

A

Sympathetic nervous system

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14
Q

What does erythropoietin do and what releases it?

A

It is released from the kidney in order to stimulate RBC production

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15
Q

Name a K sparing diuretic

A

Amiloride

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16
Q

Name a loop diuretic

A

Torsemide

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17
Q

Name a diuretic

18
Q

Where are intercalated cells and why are they called this?

A

In the collecting duct and because they have lots of mitochondria

19
Q

What does spironolactone do?

A

Compete for aldosterone receptors

20
Q

What does aldosterone do?

A

Upregulate Na pumps and make more so that more Na is excreted

21
Q

What direction does K and Na generally go?

A

K is removed and Na is added in

22
Q

What do diuretics do?

A

Increase how much salt goes into the tubules so more water is lost

23
Q

By retaining more water, what happens?

A

Blood pressure increases

24
Q

What part of the renal system fine tunes K?

A

Collectign duct

25
Which ions can pass in between cells?
Na, K, Ca and Mg
26
Which pump do thiazides act on?
Na/Cl in the distal tubule
27
What pump is in the DCT?
Na and Cl in
28
What pump do all elements have?
3Na out and 2K in
29
What pump does the loop of henle have?
Na, K and Cl in
30
Which organelle is alkali?
Mitochondria
31
What's the bodies optimum pH?
7.35-7.45
32
What do increased K+ levels cause?
Low blood pH
33
What may lower K+ levels?
Acidosis
34
What will increase K+ secretion?
Increased tubular flow
35
What stimulates K+ channels?
Aldosterone
36
Why is urine acidic?
We excrete H and reabsorb HCO3
37
What 4 things in the body act as buffers?
Protein HCO3 Hb Plasma
38
How do you work out bodily pH?
pKa + log (HCO3 in kidneys)/(CO2 in lungs)
39
What levels will the brain stem respiratory system respond to?
CO2 O2 H+
40
What are the features of alkalosis?
Lots of HCO3 so lots of CO2 is made
41
What are the features of acidosis?
Not much CO2 as all the HCO3 is being used to neutralise it
42
Name 3 pumps in the tubule
H in Na out/NH4 in Glut out/Na in