OCB02 Flashcards

1
Q

GSC

A

Gingival

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2
Q

DPSC

A

Dental pulp

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3
Q

DFPC

A

Dental follicle

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4
Q

SHED

A

Stem cells from human exfoliated teeth

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5
Q

TGPC

A

Tooth germ progenitor cells

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6
Q

iPSC

A

Induced pluripotent

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7
Q

PDLS

A

Periodontal ligament

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8
Q

ESC

A

Embryonic

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9
Q

EOSC

A

Oral mucosa epithelial

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10
Q

GMSC

A

Gingival mucosa

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11
Q

Where do dental pulp cells come from?

A

Neural crest cells

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12
Q

What do mesenchymal cells do?

A

Grow and repair organs

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13
Q

When does primary dentine stop being formed?

A

When the bottom of the root shuts

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14
Q

What is gastrulation and where does it occur?

A

Forming the 3 germ layers in the inner cell mass

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15
Q

What does the mesoderm form?

A

Everything else

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16
Q

What does the endoderm form?

A

GI tract including the liver and pancreas

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17
Q

What does the ectoderm form?

A

Nervous system, NCC and the skin

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18
Q

Describe the lay out around the neural tube (4)

A

Ectoderm, NCC, tube, notochord and endoderm

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19
Q

What do NCC do?

A

Direct the growth and development of the face

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20
Q

What is oligodontia?

A

No teeth, cleft palate and cancer due to genetic problems

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21
Q

What does Runx2 cause?

A

Teeth continuously made

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22
Q

What is ectodermal dysplasia?

A

No glands and weird teeth due to EDAR

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23
Q

What forms the neural plate?

A

Ectoderm

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24
Q

What does the neural plate form?

A

Neural tube

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25
What grows where the tube fuses?
Hindbrain
26
Where is the primitive streak found and what is it derived from?
Neural plate | Mesoderm
27
What forms somites?
Mesoderm
28
Where do cells from the streak move to?
The notochord
29
How is head to tail decided?
When cells leave the streak
30
How is belly to back decided?
Where the cells are placed on the streak
31
Describe what the primitive streak forms top to bottom
Vertebrae, muscles, heart, kidney, belly
32
What cells forms the neural plate?
Epiblast calls
33
What forms the blastocyst? (3)
Trophoblast, epiblast then hypoblast
34
What does the trophoblast form?
Placenta
35
What does the inner cell mass formed from?
Hypoblast and epiblast
36
What does the epiblast form?
Ectoderm
37
What does the hypoblast form?
Endoderm
38
What causes proliferation and the epithelium?
BMP4, FgF and Shh
39
What does bmp stimulate?
Cell death
40
What is under the enamel knot?
Dental papilla
41
What does the homeobox do?
Genes that control other genes expression
42
What gene decides how many cusps will form?
Barx1
43
When does the enamel knot form and why?
At the bud stage as the mesenchyme signals it to do so
44
What genes contribute to cusp formation?
Eda and Shh
45
What forms the oral epithelium?
Ectoderm
46
Where is the oral epithelium?
At the top of the circle
47
Where is the dental mesenchyme?
In the bottom middle of the circle
48
In the bell stage what type of tissue makes up the top and bottom?
The top is the epithelial and the bottom is the mesenchyme and NCC
49
What does mesenchyme form?
Dentine, pulp, cementum, alveolar bone and PDL
50
What does the epithelial form?
Enamel
51
What comes from the dental follicle?
Cementum, PDL and alveolar bone
52
What does the dental papilla form?
Dentine and pulp
53
Name the 4 different type of cementum
Extrinsic acellular at the crown Mixed cellular at the bottom of the root Intrinsic cellular in the middle of the root Extrinsic acellular at the edge of the root
54
What does aceullar mean?
It doesn't contain cells
55
What is cortical and trabecular bone?
The outside of the bone and in the inside of the bone
56
What is the difference between maxilla and mandible bone?
Mandible bone is regular where as maxilla is irregular
57
Where are osteoclasts found?
In howships lacunae
58
What do bone lining cells do?
Move P and Ca into and out of bone
59
What sits next to the HERS? (2)
Odontoblasts and the dental follicle
60
When the HERs finishes what comes above it?
Rests of malassez which are next to cementum
61
What connects cementum and bone?
Collagen
62
What happens to pulp in the elderly?
It gets more fibrous and smaller
63
What may cause pulp inflammation?
Caries, toxins, bacteria and trauma
64
What is taurodontism?
When the pulp splits too low
65
What does the pulp do? (4)
Make/repair dentine, form roots, protect against infection and cause eruption
66
What happens when pulp becomes inflamed?
Capillaries invade
67
What does dentinogensis imperfecta cause?
Narrow roots and bulbous canals
68
What causes pulp stones?
Tertiary dentine
69
What are sclerosed canals?
Dentine filled canals
70
What are lateral canals?
Ones off the sides
71
What are accessory canals?
Ones at the bottom
72
What's the difference between coronal and reticular pulp?
Pseudostratified columnar while there is reticular has simple columnar and coronal is at the top while radicular is in the canals
73
Where is the disc found in the TMJ?
On top of the condyle
74
Where is the coronoid and condyle?
Coronoid is at the front and the other at the back
75
Which bones of the TMJ are muscle attachments?
Coronoid and the angle
76
What type of joint is the TMJ?
Hinge and gliding joint
77
What is the ligament called that moves with the bone?
Mandibular fossa attached to the condyle
78
What cartilage is in the TMJ?
Secondary