Bone Physiology Flashcards

(41 cards)

1
Q

What are the primary functions of bones?

A
  • Muscle attachment
  • Protection and support of soft materials
  • Blood cell production
  • Storage of minerals and some triglycerides

These functions highlight the essential roles bones play in the human body.

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2
Q

What is ossification?

A

The process of bone formation

Ossification is also known as osteogenesis.

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3
Q

In what situations do bones form?

A
  • During embryological and fetal development
  • When bones grow before adulthood
  • When bones remodel
  • When fractures heal

Each situation outlines a different aspect of bone development and maintenance.

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4
Q

What are the two forms of ossification?

A
  • Intramembranous bones
  • Endochondral bones

These forms describe how bones develop from connective tissue or cartilage.

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5
Q

What type of bones form as intramembranous bones?

A

The broad, flat bones of the skull

Intramembranous ossification involves the direct formation of bone from connective tissue.

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6
Q

What are osteoblasts?

A

Cells that deposit a bony matrix around themselves

When completely surrounded by the matrix, osteoblasts become osteocytes.

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7
Q

What is the periosteum?

A

Connective tissue that surrounds the diaphysis of bones

It nourishes, protects, and provides attachment for tendons and ligaments.

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8
Q

What is the role of osteoprogenitor cells in intramembranous bone formation?

A

They cluster in ossification centers and become osteoblasts

This process initiates the formation of bone tissue.

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9
Q

What is compact bone known for?

A

Providing protection and support

Compact bone is dense and forms the outer layer of bones.

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10
Q

What is spongy bone’s characteristic?

A

Lightweight and provides tissue support

Spongy bone contains trabeculae and is found at the ends of long bones.

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11
Q

Where are osteocytes located?

A

Within lacunae that lie in concentric circles around central canals

This arrangement is crucial for nutrient and gas exchange.

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12
Q

What connects central canals in compact bone?

A

Transverse perforating (Volkmann’s) canals

These canals allow nerves and vessels to connect through the bone.

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13
Q

What is the medullary cavity?

A

The hollow space within the diaphysis of long bones

It stores yellow bone marrow and reduces the weight of the bone.

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14
Q

What occurs during the reactive phase of fracture healing?

A

An early inflammatory phase where blood vessels break and a fracture hematoma forms

This phase lasts several weeks.

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15
Q

What vitamins are important for bone growth?

A
  • Vitamin D
  • Vitamin C
  • Vitamin A
  • Vitamin K
  • Vitamin B12

Each vitamin plays a specific role in bone health and function.

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16
Q

What is a greenstick fracture?

A

A partial fracture where one side of the bone is broken and the other side bends

This type of fracture typically occurs in children.

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17
Q

What is appositional growth in bones?

A

The thickening of bones through the action of osteoblasts and osteoclasts

This process allows bones to increase in diameter.

18
Q

What role does parathyroid hormone (PTH) play in bone health?

A

Stimulates osteoclasts to increase bone resorption and release calcium into the bloodstream

PTH is crucial for maintaining calcium levels in the body.

19
Q

What type of marrow occupies the spongy bone?

A

Red marrow

Red marrow is responsible for the formation of blood cells.

20
Q

What is the role of calcitonin in bone metabolism?

A

Inhibits osteoclasts and accelerates calcium deposits in bone

Calcitonin helps lower blood calcium levels.

21
Q

What happens to bone mass in post-menopausal women?

A

They experience a decrease in bone mass as resorption outpaces deposition

This can lead to osteoporosis.

22
Q

What is the primary function of yellow marrow?

A

Stores fat and occupies most cavities of bone in adults

Yellow marrow is important for energy storage.

23
Q

What type of fracture is a Pott fracture?

A

Fracture of the distal end of the fibula with serious injury to the distal tibial articulation

This type of fracture commonly affects the ankle.

24
Q

What is the role of osteoclasts in bone remodeling?

A

Tear down bone tissue

They are essential for bone resorption.

25
What is the significance of trabeculae in spongy bone?
Allows for reduction of weight and provides space for red bone marrow ## Footnote Trabeculae are the structural features that give spongy bone its lightweight property.
26
What are the components of a lever?
* A rigid bar or rod * A pivot or fulcrum * An object that is moved against resistance * A force that supplies energy ## Footnote These components are essential for understanding how bones function in movement.
27
What is the primary function of the periosteum?
Nourish, protect, and provide attachment for muscles ## Footnote The periosteum is connective tissue surrounding the diaphysis of bones.
28
What is stored in the medullary cavity?
Yellow bone marrow ## Footnote The medullary cavity also reduces the weight of the bone.
29
What is the function of the endosteum?
Thin membrane lining the medullary cavity ## Footnote The endosteum plays a role in bone growth and repair.
30
What are the parts of a long bone?
* Diaphysis (bone shaft) * Epiphysis (both ends of the bone at the joints) * Metaphysis (region between diaphysis and epiphysis) ## Footnote The epiphysis is covered by articular cartilage.
31
What percentage of the extracellular matrix of bone is made up of collagen fibers?
30% ## Footnote The extracellular matrix also contains 55% minerals and 15% water.
32
What is calcification in bones?
The process where calcium phosphate combines with calcium hydroxide to produce crystals of hydroxyapatite ## Footnote This process fills spaces produced by collagen fibers.
33
What defines the hardness of bones?
Minerals ## Footnote Collagen defines flexibility and tensile strength.
34
How are bones classified by shape?
* Long (e.g., thigh bones) * Short (e.g., ankles) * Flat (e.g., ribs, skull) * Irregular (e.g., vertebrae) * Sesamoid (e.g., kneecap) ## Footnote Each classification reflects the bone's function and location.
35
What is one function of bones related to the body's support?
Provide support for the body’s weight ## Footnote Bones such as the pelvis and lower limbs are critical for this function.
36
What is the role of osteoprogenitor cells?
Bone stem cells able to differentiate into other types of bone cells ## Footnote They play a crucial role in bone growth and repair.
37
What do osteoblasts do?
Bone-building cells that secrete matrix ## Footnote They are essential for bone formation.
38
What is the function of osteocytes?
Mature bone cells ## Footnote They maintain bone tissue.
39
What is the role of osteoclasts?
Remodel bones and cause them to release calcium ## Footnote They are important for bone resorption and calcium homeostasis.
40
True or False: The bones of the skull protect the brain.
True ## Footnote Bones provide protection for vital organs.
41
Fill in the blank: The extracellular matrix of bone is comprised of 30% collagen fibers, 55% minerals, and _______.
15% water ## Footnote This composition is crucial for bone structure and function.