bones Flashcards

(99 cards)

1
Q

functions of skeletal system

A

Body support, Organ protection, Body movement, . Mineral storage, Blood cell production.

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2
Q

The principal
minerals stored in bones which are two minerals essential for many
physiological processes.

A

calcium and phosphorous

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3
Q

stored within bone cavities. If needed,
the lipids are released into the blood and used by other tissues as a source of energy.

A

adipose tissue

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4
Q

mature bone matrix is normally about ___ organic and ___inorganic
material.

A

35 ; 65

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5
Q

The organic material consists primarily of

A

collagen and proteoglycans

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6
Q

The
inorganic material consists primarily of a calcium phosphate crystal called

A

hydroxyapatite

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7
Q

Brittle bone disease also known as

A

osteogenesis imperfecta

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8
Q

which means imperfect bone
formation, is a rare disorder caused by any one of a number of faulty genes that
results in either too little collagen formation, or poor quality collagen. As a result,
the bone matrix has decreased flexibility and is more easily broken than normal
bone.

A

brittle bone disease

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9
Q

bone-building cells. These cells have an extensive endoplasmic reticulum and numerous ribosomes

A

osteoblasts

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10
Q

Osteoblasts produce

A

collagen and proteoglycans

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11
Q

high concentrations of Ca2+ and
phosphate ions, forming crystals called

A

hydroxyapatite

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12
Q

The formation of new bone by osteoblasts is called

A

ossification or osteogenesis

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13
Q

This type of growth adds new layers to the outer surface of the existing material

A

appositional growth

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14
Q

Osteoblasts become

A

osteocytes

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15
Q

Osteocytes account for ___ of bone
cells and are very long-lived, with a life span of up to ____years.

A

90-95% ; 25 years

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16
Q

Osteocyte cell bodies are housed within the bone matrix in spaces called

A

lacunae

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17
Q

Osteocyte cell extensions are housed in narrow, long spaces called

A

canaliculi

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18
Q

are bone-destroying cells

A

osteoclast

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19
Q

Breakdown of bone is called

A

bone reabsportion

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20
Q

massive, multinucleated cells and develop from the red bone
marrow cells that also differentiate into specialized white blood cells.

A

osteoclasts

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21
Q

specialized reabsorption-specific area of the membrane.

A

ruffled border

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22
Q

Mature bone is called

A

lamellar bone

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23
Q

It is organized into thin, concentric sheets or layers, called

A

lamellae

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24
Q

These are mature bone cells located in small spaces called lacunae

A

osteocytes

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25
Osteocytes are connected to each other through tiny channels that allows them to share nutrients and signals is called
canaliculi
26
looks porous and has a less dense structure than compact bone
spongy bone
27
spongy bone contains interconnecting rods or plates of bone known as
trabeculae
28
The spaces between trabeculae are filled with
bone marrow and blood vessels
29
forms the solid outer layer of bones and is denser with less space than spongy bone.
compact bone
30
Blood vessels penetrate this dense bone, running through the central canals.
compact bone
31
Compact bone also known as
cortical bone
32
The functional unit of compact bone is an
osteon or haversian system
33
composed of concentric rings of matrix, which surround a central tunnel and contain osteocytes.
osteon
34
an osteon resembles a circular target; the bull’s-eye of the target is the
central canal
35
are lined with endosteum and contain blood vessels, nerves, and loose connective tissue
central canals
36
Nutrients in the blood vessels are delivered to the
osteocytes
37
the center portion of the bone
diaphysis
38
It is composed primarily of compact bone tissue, surrounding a hollow center called the
medullary cavity
39
The ends of a long bone are called
epiphyses
40
are mostly spongy bone, with an outer layer of compact bone.
epiphyses
41
Within joints, the end of a long bone is covered with hyaline cartilage called
articular cartilage
42
located between the epiphysis and the diaphysis
epiphyseal or growth plate
43
Growth in bone length occurs at the
epiphyseal plate
44
When bone stops growing in length, the epiphyseal plate becomes ossified and is called the
epiphyseal line
45
The cavities of spongy bone and the medullary cavity are filled with
marrow
46
the site of blood cell formation
red marrow
47
mostly adipose tissue.
yellow marrow
48
In the fetus, the spaces within bones are filled with
red marrow
49
connective tissue membrane covering the outer surface of a bone
periosteum
50
single cell layer of connective tissue that lines the internal surfaces of all cavities within bones, such as the medullary cavity of the diaphysis and the smaller cavities in spongy and compact bone
endosteum
51
Intramembranous ossification of this membrane begins at approximately the eighth week of embryonic development and is completed by approximately 2 years of age.
52
The locations in the membrane where intramembranous ossification begins are called
centers of ossification
53
expand to form a bone by gradually ossifying the membrane.
centers of ossification
54
have the oldest bone, and the expanding edges the youngest bone
centers
55
soft spots, are the larger, membrane-covered spaces between the developing skull bones that have not yet been ossified
fontanels
56
The bones eventually grow together, and all the fontanels have usually closed by ____ years of age.
2
57
The formation of cartilage begins at approximately the end of the _____ of theembryonic development
fourth week
58
Endochondral ossification of some of this cartilage starts at approximately the
eighth week
59
produced by cells called chondrocytes (KON-droh-sites), and has the approximate shape of the future bone. The cartilage model is surrounded by perichondrium.
hyaline cartilage model
60
A hyaline cartilage model is produced by cells called
chondrocytes
61
Once osteoblasts begin to produce bone, the perichondrium becomes the
periosteum
62
The osteoblasts produce compact bone on the surface of the cartilage model, forming a
bone collar
63
occurs as a result of continuous cell division of the chondrocytes within the cartilage model.
Interstitial growth
64
occurs as a result of cell division at the surface of the cartilage model, and under the perichondrium.
appositional growth
65
hypertrophy or
enlarge
66
the chondrocytes in the center of the cartilage model absorb some of the cartilage matrix resulting in
hypertrophy or enlargement
67
also initiate the formation of hydroxyapatite crystals in the cartilage matrix
chrondrocytes
68
enlarged lacunae with thin walls of calcified matrix is. result of
death of chrondrocytes
69
forms as osteoblasts produce bone on the surface of the calcified cartilage. The osteoblasts transform the calcified cartilage of the diaphysis into spongy bone.
primary ossification center
70
Osteoclasts remove bone from the center of the diaphysis to form the
medullary cavity and cells to form red bone marrow
71
created in the epiphyses by osteoblasts that migrate into the epiphysis. the spaces in the epiphyses do not enlarge to form a medullary cavity as in the diaphysis.
Secondary ossification center
72
After a person’s bones have stopped growing, the epiphyseal plate regresses into a “scar, ” called the
epiphyseal line
73
occurs between approximately 12 and 25 years of age, depending on the bone and the individual.
closure of the epiphyseal plate,
74
bone that becomes old is replaced with new bone in a process called
bone remodeling
75
localized mass of blood released from blood vessels but confined within an organ or a space.
hematoma
76
mass of bone tissue that forms at a fracture site. Several days after the fracture, blood vessels grow into the clot
callus
77
produce collagen and other extracellular materials to form granulation tissue, the precursor to healed tissue
fibroblast
78
a connective tissue that contains collagen, ground substance, and other organic molecules, as well as water and minerals.
bone
79
cartilage
covering
80
(reduces wear and tear on the joint surfaces)
cartilage
81
muscle to bone attachment
tendon
82
bone to bone
ligament
83
minimal movement (stabilizer)
ligament
84
Longer than they are wide
long bones
85
Has a central shaft
long bones
86
Mostly located on the upper and lower limbs
long bones
87
This shape enhances their functional movement of the limbs.
long bones
88
Long as they are wide.
short bones
89
Allows stability and facilitates some movement
short bones
90
Relatively thin, flattened shape.
flat bones
91
They are well suited to provide strong barrier around soft organs.
flat bones
92
Have shapes that do not fit readily into the other three categories
irregular bones
93
Occurs when osteoblasts begin to produce bone in connective tissue membranes. Primarily happens in skull and clavicle.
intramembranous
94
Occurs when osteoblasts begin to produce bone in the hyaline cartilage. Primarily happens in bones except skull and clavicle.
endochonral
95
Formation of bone by osteoblasts
bone ossification
96
Involves the synthesis of an organic matrix containing collagen and proteoglycans and the addition of hydroxyapatite crystals to the matrix.
bone ossification
97
Can be either INTRAMEMBRANOUS or ENDOCHONDRAL
bone ossification
98
Involves the removal of existing bone by osteoclasts and the deposition of new bone by osteoblasts
bone remodeling
99
Responsible for changes in bone shape, bone repair, adjustment of bone to stress, and calcium ion regulation
bone remodeling