Bones Flashcards

0
Q

5 functions of bones

A
Framework 
Protection
Attachment
Movement
Haemopoeisis
Mineral reservoir
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1
Q

How many bones in the body

A

206

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2
Q

What is the formation/development of blood cells called

A

Haemopieisis

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3
Q

2 types bone tissue

A

Spongy

Compact

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4
Q

3 types bone cells

A

Osteoblasts
Osteoclasts
Osteocyte

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5
Q

What is an osteoblast

A

Bone building cell

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6
Q

What is osteo last

A

Bone dissolving cells

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7
Q

Which bone cells are multi-nucleated

A

Osteoclasts

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8
Q

What is the name of the process in which Osteoclasts dissolve the bone cells

A

Bone resorption

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9
Q

What is an osteocyte

A

Mature bone cell in lacunae

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10
Q

4 parts of Osteon

A

Lamella
Lacunae
Canaliculi
Central canal

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11
Q

Basic unit of compact bone is?

A

osteon

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12
Q

Describe lamellar

A

Extracellular matrix
Contains minerals/collagen fibres
Tubular

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13
Q

Describe lacunae

A

‘Lagoons’
Spaces between lamellae
Contain osteocytes

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14
Q

Describe canaliculi

A

Network of canals

So osteocytes can receive nutrients/remove waste

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15
Q

What does central canal of compact bone contain

A

Blood vessels and nerves

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16
Q

What doesn’t spongy bone have that compact does

A

Osteons

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17
Q

Describe structure of spongy bone

A

Columns of bone -trabeculae

In irregular lattice

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18
Q

What do trabeculae contain as well as osteons

A

Lamellae
Osteocytes
Lacunae
Canaliculi

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19
Q

What are spaces between trabeculae filled with

A

Bone marrow

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20
Q

What does bone marrow do

A

Make blood cells

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21
Q

Outer covering of compact bone

A

Periosteum

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22
Q

Larger 2 types canals in compact bone

A

Volkmans (L-R)

Haversian up down

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23
Q

Long shaft of bone

A

Diaphysis

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24
Ends of bone
Epiphyses
25
Describe long bone
Cylindrical Curve 2 planes greater strength
26
What is epiphyseal growth plate
Hyaline cartilage 'disc' bordering epiphyses, around which growth occurs.
27
Structure of epiphysis
Thin outer compact bone covered by hyaline cartilage capsule Inner spongy bone with red marrow/myeloid tissue Epiphyseal growth plate
28
What covers outside of diaphysis
Periosteum
29
Myeloid tissue
red bone marrow
30
What is periosteum
Vascular, connective tissue membrane covers outer diaphysis
31
What lines central medullary canal in diaphysis
Endosteum
32
All bone marrow starts off as -
Red bone marrow
33
In severe blood loss what can happen to the marrow
Yellow can convert to red
34
Structure of diaphysis
Outer compact bone covered by periosteum | Central medullary canal contains red marrow/myeloid tissue/yellow blood cells lined with endosteum.
35
2 layers of periosteum
Outer - tough, fibrous,protects Inner - CAMBIUM - contains osteoblasts & osteoclasts important for growth/repair.
36
What replaces periosteum on joint surfaces
Hyaline cartilage
37
5 jobs of periosteum
``` Protect bone Bone growth/repair Attachment for ligaments/tendons Provides blood supply Has nociceptors-nerve endings sense pain ```
38
5 bone shapes in body
``` long short irregular flat sesamoid ```
39
Example of long bone
femur
40
ex of short bone
carpals/tarsals
41
ex flat bone
skull/hip
42
ex irregular bone
vertabrae
43
ex sesamoid bone
patella
44
structure of all bones apart from long -
peroisteum enclosing compact bone outer spongy inside, containing bone marrow
45
What does red bone marrow do
creates red blood cells, platelets, white blood cells
46
what does yellow bone marrow do?
stores fat | creates some white blood cells
47
Why is exercise particularly important in older women?
To help strengthen their bones after menopause | prevent Osteoporosis
48
Bone formation known as
ossification/osteogenisis
49
3 times ossification/genesis occurs
during growth continuous bone renewal repair
50
2 types ossification
Intramembraneous ossification | Endochondral ossification
51
What are cartilage cells known as?
Chodrocytes
52
Describe intramembraneous ossification
Bones form directly within the mesenchyme
53
Describe Endochondrial Ossification
Bones form within hyaline cartilage at epiphyseal plate
54
what is mesenchyme
cell soup
55
By which process are bone cells produced around the epiphyseal growth plate during endochondrial ossification?
Mitosis
56
Which cells ossify the matrix to form bone during endochondrial ossification?
Osteoblasts
57
At what age doe endochondrial ossification cease?
early 20's boys | late teens girls
58
What are our bones left with after completely ossifying
epiphyseal line
59
what is the growth in bone thickness known as
appositional growth
60
inner layer of periosteum called?
cambium
61
Describe how diameter of bone increases during appositional growth
Osteoblasts in cambium form compact bone | Osteoclasts in medullary cavity carve out bone
62
Main hormones affecting bone growth in children
Growth hormone | thyroid hormone
63
Main hormones affecting bone growth in adults
testosterone & oestrogen calcitonin parathyroid hormone
64
What to take for restless legs
magnesium glycinate
65
Which mineral do bones store large amounts of?
Bone is an important calcium reservoir
66
Blood calcium levels have to be tightly controlled to ensure proper
blood clotting | nerve & muscle function
67
If blood calcium levels are low what happens in body to restore homeostasis
Osteoclasts break down/release calcium into blood
68
If blood calcium levels are high what happens to restore homeostasis
Calcium in absorbed back into the bone via Osteoblasts
69
Which two glands regulate calcium exchange
Parathyroid | thyroid
70
Describe negative feedback system that increases blood calcium
RECEPTORS - parathyroid gland detect lower calcium CONTROL CENTRE - switches on PTH gene PTH stimulates the EFFECTORS - Osteoclasts (bone resorption)/Kidneys keep the calcium in blood
71
Describe negative feedback system that decreases blood calcium
come back
72
What helps bones get stronger
weight bearing exercise
73
Which type of exercise doesn't help bone strength
swimming
74
What rate of bone mass loss a week can astronauts/the bedridden expect?
Up to 1% per week
75
Exercise leads to increased ---- and --- in bones
increased mineral deposition and increased production of muscle fibres
77
What helps to ensure bone formation occurs more quickly than bone resorption
exercise
78
what is the bioactive form of vit D?
calcitrol
79
what is calcitonin?
hormone that promotes bone growth & decreases blood calcium when too high