Immunosuppressive dose of Dex in cattle
0.2mg/kg
Allergic rhinitis is what type of hypersensitivity? Which cells are causing the tissue damage?
Type 1
repeated tissue damage by mast cells
Disease associated with these clinical signs:
- -sudden onset of dyspnea
- -profuse bilateral nasal discharge (mucopurulent)
- -intense pruritis, sneezing
- -granulomas with intact mucosa
Allergic rhinitis
Concerning sinusitus, name the two most common causes and which sinuses are affected
1) dehorning–frontal sinus
2) tooth root abscess–maxillary sinus
Most common agent associated with necrotic laryngitis?
Fusobacterium necrophorum
Inciting cause for most cases of necrotic laryngitis
laryngeal contact ulcers from respiratory viruses
the bacteria can’t penetrate intact mucous membranes
This disease is characterized by:
- -sudden onset of moist, painful cough
- -depression, anorexia, and fever
- -a palpably swollen larynx
Necrotic laryngitis
What type of pneumonia is commonly associated with shipping fever complex
cranioventral bronchopneumonia
Two major differences in the clinical appearance of animals with a bacterial vs. viral infection
Viral:
higher fever than bacterial
viral infected will be more alert (bacterial= more depressed)
Where does a virus remain latent if it’s:
1) alpha herpes
2) gamma herpes
1) CNS tissue (BHV-1)
2) lymphoid tissue (OHV-1/AHV-1)
Infectious bovine rhinotracheitis (IBR) is caused by?
BHV-1 (1.1, 1.2a & 1.2b)
These clinical signs are indicative of what disease:
- -high fever
- -clear nasal discharge that progresses to mucopurlent as disease progresses
- -increased BV sounds (but no other abnormal noises)
- -conjunctivitis with ocular discharge
IBR (red nose)
T/F: Pulmonic pasteurellosis may be a sequel to IBR and the two diseases may occur simultaneously
TRUE
Two biotypes of BVDV? Which is more common?
Non-cytopathic (more common)
Cytopathic
Most herds with ____ BVDV will have ________ infections
endemic; subclinical infections
How does BVDV cause respiratory tract infections?
it’s immunosuppressive (allows co-infection with other pathogens)
Diagnostic method of choice for BVDV?
How would you NOT diagnose persistently infected animals?
Virus isolation
Can’t diagnose PI animals with virus isolation using lung biopsy
This virus causes mild to unapparent disease in younger cattle & is considered to be endemic in most cattle populations
PI-3 (parainfluenza)
Which diagnostic method is not helpful in diagnosing infections with PI-3? Why?
single serum specimens
Ab prevalence is very high–hard to find cattle without serological evidence of infection
Pasteurellosis in cattle is most commonly associated with infection by:
Mannheimia haemolytica (Biotype A, serotype 1)
sometimes P. multocida
3 important virulence factors associated with M. haemolytica
leukotoxin
endotoxin
capsular polysaccharides
Pasteurellosis (in necropsy) causes ______ of the lungs
hepatization (looks like liver)
This bacteria can cause a myriad of clinical signs due to the numerous systems it can affect (complex)
H. somni
A non-febrile and non-infectious respiratory disease in cattle linked to grazing of lush pastures
Acute Bovine pulmonary emphysema and edema (ABPEE)
Describe the pathophysiology of APBEE
cattle change from dry grazing to lush pastures that contain high concentrations of L-tryptophan
L-tryptophan is formed into 3-methylindole (3MI) in the rumen–>goes to blood stream–>lungs
Clara cells of the lungs convert 3MI to 3-methylindolamine–>leads to overgrowth of type II pneumocytes, edema, and emphysema
Two drugs that can be used to prevent ABPEE? How do they work?
Monensin & Lasalocid
help decrease 3MI production in the rumen
Infection with BRSV is associated with what type of pneumonia
atypical/acute interstitial pneumonia
Most common cause of TB in cattle?
Mycobacterium bovis
Which disease causes:
- -progressive weight loss
- -suppressed, moist cough that isn’t paroxysmal
- -retropharyngeal ln enlargement
- -potential for GI signs
TB
Primary test for diagnosing cattle with TB?
Caudal fold tuberculin test
Which 2 bacteria are commonly associated with caval syndrome
Fusobacterium necrophorum (most common)
Trueperella pyogenes
The most common pathophysiology off caval disease?
Liver abscesses secondary to rumenitis (due to high grain diet)
2 common causes of pleural disease in cattle?
Lymphosarcoma
Hardware disease