Cancer Flashcards

(32 cards)

1
Q

Cellular growth, not responding to regulation processes

A

neoplasm

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2
Q

Dysplasia leads to

A

neoplasia

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3
Q

Generally the neoplasms are due to a

A

mutation

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4
Q

Characteristics of cancer

A

rapid
uncontrolled proliferation
loss of differentiation

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5
Q

Is the formation of cancer

A

carcinogenesis

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6
Q

Stages of carcinogenesis

A
  1. Initiation
  2. Promotion
  3. Progression
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7
Q

Stage of carcinogenesis that involve the exposure of the cells to environmental events such as DNA mutation, chemical, viruses or radiation

A

initiation

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8
Q

Stage of carcinogenesis where the mutated cells are exposed to hormones and promote the growth

A

promotion

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9
Q

Stage of carcinogenesis where the tumor invades and metastasizes

A

progression

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10
Q

In the stage of progression in the carcinogenesis the damage is

A

irreversible

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11
Q

Protein products that stimulate the cell growth and division

A

oncogenes

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12
Q

Is the positive regulation of cell cycle

A

oncogenes

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13
Q

What is an proto-oncogene?

A

precursor of oncogene

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14
Q

Is the negative regulation of cell cycle

A

tumor suppressor gene

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15
Q

Protein products stop cell cycle and promote apoptosis

A

tumor suppressor gene

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16
Q

The tumor suppressor gene is involved in

17
Q

Tumor suppressor genes in normal cells

A

prevent cancer

18
Q

DNA changes that inactivate tumor suppressor genes can lead to

A

uncontrolled cell growth

19
Q

A tumor could be

A

benign or malignant

20
Q

Type of tumor that are usually encapsulated

21
Q

A benign tumor ir encapsulated, that means that can’t

22
Q

Type of tumor that has an irregular shape and surface

23
Q

The malign tumor is encapsulated

24
Q

A malignant tumor needs _____ to survive

25
Clinical manifestations of cancer
``` anemia cachexia fatigue infections leukopenia thrombocytopenia pain ```
26
Is the decrease in the synthesis of leukocytes
leukopenia
27
Low platelets level
thrombocytopenia
28
Infections in cancer are due to
bone marrow depression
29
Anemia in cancer is due to
bad nutrition | chronic bleeding
30
Diagnosis for cancer
1. Identify cancer cells 2. Establish the cytology 3. Type of cancer cells
31
The systemic effects of neoplasia could be
direct or indirect
32
Type of systemic effect of neoplasia that is unpredictable
indirect