Wound Healing

Question 1

A successful ____ maintains tissue function and repair tissue barrier, preventing blood loss and infection, but it is usually accomplished through collagen deposition or scarring

Answer 1

wound healing

Question 2

Mention the steps of the basic processes of healing

Answer 2

1. Hemostasis
2. Inflammation process and cellular migration
3. Cell proliferation
4. Extracellular matriz organization and remodeling

Question 3

Is the steps that control the bleeding in the injury

Answer 3

hemostasis

Question 4

Type of hemostasis

Answer 4

Primary and secondary

Question 5

Goal of the primary hemostasis

Answer 5

Platelet plug formation

Question 6

Goal of the secondary hemostasis

Answer 6

Clot formation

Question 7

Describe the process of primary hemostasis

Answer 7

Local vasoconstriction
Adhesion
Platelet activation
Aggregation

Question 8

Mention the 3 pathways of secondary hemostasis

Answer 8

Extrinsic pathway
Intrinsic pathway
Common pathway

Question 9

Extrinsic and intrinsic pathway both converge in

Answer 9

common pathway

Question 10

____ allows the conversion between extrinsic and intrinsic pathway

Answer 10

Factor Xa

Question 11

All the pathways of secondary hemostasis have in common the

Answer 11

Factor Xa

Question 12

Cellular migration last

Answer 12

several days (3-5)

Question 13

Steps of cellular migration

Answer 13

1. Migration begins
2. Angiogenic factor
3. Pericyte migration
4. Growth factors
5. Reepithelization

Question 14

Step of cellular migration that reclute cells from circulation or bone marrow

Answer 14

Migration begins

Question 15

Step of cellular migration where monocytes, macrophages secrete grows factor to release the angiogenesis

Answer 15

Angiogenic factor

Question 16

Step of cellular migration that stimulate the process of angiogenesis

Answer 16

pericyte migration

Question 17

Step of cellular migration where the fibroblast migrate to the wound

Answer 17

Growth factors

Question 18

Step of cellular migration where queratinocites penetrate the wound

Answer 18

Reepithelization

Question 19

Are important players facilitating the inflammatory proliferative phase transition during wound healing

Answer 19

Macrophages

Question 20

Excessive and prolonged inflammation result in _____ and increased scar formation

Answer 20

delayed healing

Question 21

There are an increased of neutrophils

Answer 21

inflammation

Question 22

There are an increased of anti inflammatory mediators and growth factors

Answer 22

proliferation

Question 23

Is the best moment to use NSAIDs

Answer 23

proliferation

Question 24

If the transition from inflammation to proliferation doesn’t exist the wound healing

Answer 24

does not occur

Question 25

Goal of the remodeling in wound healing

Answer 25

Achieve tensile strength | Recover the normal tissue structure

Question 26

The remodeling in wound healing begins ____ after the injury

Answer 26

2-3 weeks

Question 27

Mention the forms of tissue regeneration

Answer 27

Labile Stable Permanent

Question 28

Form of tissue regeneration where the wound heal well

Answer 28

labile

Question 29

Form of tissue regeneration where there is an hyperplasia

Answer 29

stable

Question 30

Form of tissue regeneration where there is a weak regeneration capacity

Answer 30

permanent

Question 31

Tissues where we can find a labile regeneration

Answer 31

Skin, connective tissue, intestine

Question 32

Tissues where we can find a stable regeneration

Answer 32

liver

Question 33

Tissues where we can find a permanent regeneration

Answer 33

Skeletal muscle, cartilage, neurons and cardiac tissue

Question 34

Types of skin healing

Answer 34

Primary intention Secondary intention Tertiary intention

Question 35

Type of skin healing where the wound edges come together

Answer 35

primary intention

Question 36

Type of skin healing where the wound edges are too far one to another and heal by themselves

Answer 36

secondary intention

Question 37

Type of skin healing where the wound is infected so we have to leave it open

Answer 37

tertiary intention

Question 38

Is when the injured tissue returns to its original state

Answer 38

regeneration