Canine Distemper (Exam 2)

Question 1

(T/F) Canine Distemper is a systemic disease affecting multiple organs.

Answer 1

True

Question 2

Where does most disease of Canine Distemper occur?

Answer 2

shelters/rescues (lack of vax history)

Question 3

Canine Distemper often infects ________ which leads to companion animals becoming infected.

Answer 3

raccoons

Question 4

_______ are the principal reservoir host for Canine Distemper.

Answer 4

dogs

Question 5

All cats can become infected and develop clinical disease from CDV.

Answer 5

False - wild cats only

Question 6

(T/F) Domestic cats cannot become infected with Canine Distemper.

Answer 6

False - infected w/o clinical disease

Question 7

Dogs are the greatest risk for Canine Distemper are what age range?

Answer 7

3-6 months

Question 8

How is Canine Distemper transmitted?

Answer 8

aerosols (respiratory)

Question 9

Dogs infected with Canine Distemper can begin shedding by day ____ post-infection which can persistent for _____ to ____ days.

Answer 9

day 7
60-90 days

Question 10

Canine Distemper is a(n) (enveloped/nonenveloped) (DNA/RNA) virus.

Answer 10

enveloped RNA virus

Question 11

(T/F) Canine Distemper is highly resistant to heat and disinfectants.

Answer 11

False - easily destroyed

Question 12

(T/F) Canine Distemper is NOT believed to be zoonotic.

Answer 12

True

Question 13

Canine Distemper is spread through aerosols and infects __________ within 24 hours which spreads to the tonsils and bronchial lymph nodes.

Answer 13

macrophages

Question 14

Within ___ to ___ days after infection, primary viremia and multiplication of CDV occur in multiple organs such as spleen, thymus, stomach, intestines, and liver.

Answer 14

4-6 days

Question 15

After primary viremia and multiplication, fever and _________ occur during CDV infection.

Answer 15

lymphopenia

Question 16

After fever and lymphopenia, _________ occurs from day 8-10 in CDV infection.

Answer 16

secondary viremia

Question 17

During secondary viremia of CDV, what two tissue types become infected with the virus?

Answer 17

epithelium
CNS

Question 18

By day 14 of CDV infection, _____ antibody and _________ immunity block further spread of the virus.

Answer 18

IgG
cell-mediated

Question 19

(T/F) Canine Distemper can remain subclinical and not cause disease in some animals.

Answer 19

True

Question 20

In mild cases of Canine Distemper, its clinical signs are often confused with:

Answer 20

kennel cough

Question 21

What rare condition occurs when skin becomes infected by Canine Distemper?

Answer 21

hyperkeratosis

Question 22

In young and immunosuppressed dogs, CDV causes cytolytic injury to neurons, leading to a demyelinating disease and neural necrosis. This is called:

Answer 22

Acute Canine Distemper Virus Encephalitis

Question 23

(T/F) Because CDV infected many tissues in the body, it is fairly easy to determine infection when testing infected tissue.

Answer 23

False - needs to be sampled at the right time or false negative

Question 24

Serum _____ antibody tests are useful in diagnosis of Canine Distemper Virus.

Answer 24

IgM

Question 25

(T/F) It is difficult to differentiate between vaccination and an active infection of Canine Distemper Virus with a serum antibody test.

Answer 25

True

Question 26

Canine Distemper is a (core/noncore) vaccine and currently protects against all known strains.

Answer 26

core

Question 27

When vaccinated wildlife, ________ vaccine type should be used.

Answer 27

recombinant

Question 28

Which animal is a canarypox-vectored recombinant vaccine used for CDV?

Answer 28

ferrets

Question 29

Canine Herpes Virus 1 is a(n) _________-herpesvirus.

Answer 29

alpha

Question 30

Canine Herpes Virus 1 is a(n) (enveloped/nonenveloped) (DNA/RNA) virus.

Answer 30

enveloped DNA virus

Question 31

Many dogs are __________ for Canine Herpes Virus 1 so clinical disease is rare.

Answer 31

seropositive

Question 32

(T/F) Canine Herpes Virus 1 is not stable in the environment and easily destroyed by heat and disinfectants.

Answer 32

True

Question 33

Canine Herpes Virus 1 is a disease which infects which two systems?

Answer 33

respiratory system genitals

Question 34

Canine Herpes Virus 1 can remain ________ in dogs, shed intermittently, and not detected by blood samples or other testing.

Answer 34

latent

Question 35

What 3 ways is Canine Herpes Virus 1 transmitted?

Answer 35

oronasal genital maternal transmission

Question 36

__________ is not a good sample for PCR testing for CHV-1 as latent infections are not detected.

Answer 36

blood

Question 37

CHV-1 infection causes a generalized viremia which is often fatal, followed by ________.

Answer 37

hypothermia

Question 38

Grossly, CHV-1 causes _________ and ________ of multiple tissues such as kidney, liver, lung, adrenal glands, heart, intestines, and spleen.

Answer 38

necrosis + hemorrhage

Question 39

(T/F) There is no CHV-1 vaccine available in the US.

Answer 39

True