Flashcards in Carbapenems Deck (7)
Name two Carbapenem drugs.
What is the general MOA of Carbapenem drugs (Imipenem and Meropenem)?
- Same as Penicillin
How are Carbapenems (Imipenem and Meropenem) administered?
What spectrum is Imipenem and what is it used to treat?
- Very broad spectrum (Gram +ve, Gram -ve and anaerobic)
- Not active against MRSA
* Treats: severe nosocomial infections
What drug interactions occur with Imipenem?
- Imipenem + Cilastin = block renal metabolism
What spectrum is Meropenem and what is it used to treat?
* Meningitis alternative treatment (good CSF penetration)