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Flashcards in Other Drugs Deck (7)
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1

What is the MOA of Fosfomycin?

- Inhibits early cell wall synthesis
- Bactericidal

2

How is Fosfomycin eliminated?

- Urine
- Breast milk

3

How is Fosfomycin administered?

- Oral

* Delayed by food (2 hours before)(3 hours after)

4

What spectrum is Fosfomycin and what is it used to treat?

- Broad (Gram +ve and Gram -ve)
- Synergistic with B lactams, aminoglycosides and quinolones

- UTI in women/girls older than 5 years (single dose)
- Prophylaxis: diagnostic and transurethral procedures in men

5

What are the side effects of Fosfomycin?

- GIT issues, skin rashes

6

What drug interactions occur with Fosfomycin?

- Metoclopramide (decreases concentration)

7

What is contra-indicated with Fosfomycin?

- Renal failure
- Pregnancy
- Lactation (excreted in breast milk)