Cardiovascular Disorders Flashcards
(150 cards)
1
Q
most common site of coronary artery occlusion
A
left anterior descending artery
2
Q
heart region supplied by left anterior descending artery
A
anterior wall of left ventricle
3
Q
heart region supplied by LAD septal branch
A
anterior 2/3 of interventricular septum
4
Q
heart region supplied by left coronary circumflex branch
A
left atrium, posterolateral left ventricle
5
Q
heart region supplied by right coronary posterior descending branch
A
inferior wall of left ventricle, posterior 1/3 of interventricular septum
6
Q
heart region supplied by right coronary marginal branch
A
right atrium, right ventricle
7
Q
heart region supplied by right coronary nodal branches
A
SA and AV nodes
8
Q
gold standard for identifying coronary artery disease
A
coronary aniography
9
Q
next step when exercise stress test is equivocal
A
nuclear exercise test with thallium-201 or technetium-99m-sestamibi during exercise testing
10
Q
second line when comorbidities prevent exercise stress test
A
pharmacologic stress testing with dobutamine
11
Q
age to begin screening for hyperlipidemia
A
men after age 35
women after age 45
12
Q
goal LDL for patients at high risk for CAD
A
< 100 mg/dL
13
Q
goal LDL for patients with 2+ risk factors for CAD
A
< 130 mg/dL
14
Q
goal LDL for patients with 0-1 risk factors for CAD
A
< 160 mg/dL
15
Q
HMG-CoA reductase inhibitors
A
acts on liver
decreases LDL and triglycerides
increases HDL
SE: myositis, increases LFTs
16
Q
ezetimibe
A
cholesterol absorption inhibitor acts on intestines
decreases LDL
SE: myalgias, increases LFTs
17
Q
gemfibrozil, fenofibrate
A
stimulates lipoprotein lipase in blood
decreases LDL and triglycerides
increases HDL
SE: myositis, increases LFTs
18
Q
cholestyramine, colestipol, colesevelam
A
bile acid sequestrants in GI tract
decreases LDL
increases triglycerides
SE: bad taste, abdominal discomfort
19
Q
niacin
A
acts on liver
decreases LDL, triglycerides
increases HDL
SE: flushing, nausea, pruritis, insulin resistance, gout, paresthesias, increases LFTs
20
Q
vessels most commonly used for CABG
A
saphenous vein
internal mammary artery
21
Q
pharmacotherapy for unstable angina
A
aspirin and clopidogrel (if no PTCA) GP IIb/IIIa (if PTCA) oxygen nitroglycerin heparin beta-blockers
22
Q
time limit for thrombolysis in MI
A
12 hours
use t-Pa or urokinase
23
Q
cardiac enzyme to evaluate immediate re-infarct
A
CPK-MB
decreases in 2-3 days
24
Q
risk reduction medications after MI
A
low dose ASA clopidogrel beta-blockers ACE inhibitors K-sparing diuretics HMG-CoA reductase inhibitors exercise, smoking cessation, and dietary modifications
25
V2, V3, V4 infarction
anterior infarction
| LAD artery
26
V1, V2, V3 infarction
septal infarction
| LAD artery
27
II, III, aVF infarction
inferior infarction
| posterior descending or marginal branch
28
1, aVL, V4, V5, V6
lateral infarction
| LAD or circumflex artery
29
V1, V2
posterior infarction
| posterior descending artery
30
first degree heart block
PR > 0.2 seconds
asymptomatic
caused by increased vagal tone or functional conduction impairment
31
second degree mobitz I heart block
progressive PR lengthening until skipped QRS
asymptomatic
caused by his bundle conduction defect, drug effects (beta-blockers, digoxin, calcium channel blockers), or increased vagal tone
adjust medications, consider pacemaker if symptomatic bradycardia is present
32
second degree mobitz II heart block
randomly skipped QRS without changes in PR interval
usually asymptomatic
caused by infranodal conduction problem in bundle of his or purkinje fibers
can progress to third degree heart block
treat with ventricular pacemaker
33
third degree heart block
no relationship between P waves and QRS complexes
syncope, dizziness, hypotension
absence of conduction between atria and ventricles
treat with ventricular pacemaker and avoid medications affecting AV conduction
34
next step of management in congenital heart disease with early cyanosis
prostaglandin E
35
medication that closes PDA
indomethacin
36
6 week old infant has signs of left heart failure and EKG shows left-sided MI
anomalous origin of the left coronary artery
37
most common vasculitis
temporal arteritis
38
defects of tetrology of fallot
VSD, pulmonary stenosis, RVH, overriding aorta
39
management for DVT in patient with high likelihood of falling
IVC filter
40
management of peripheral vascular disease
smoking cessation, glucose and lipid control, exercise
| cilostazol, statins, aspirin
41
indications for operating on AAA
greater than 5.5 cm
| growing more than 0.5 cm in 6 months
42
mechanism of PSVT
accessory conduction pathways through AV node
43
treatment for ventricular tachycardia
hemodynamically stable: amiodarone or lidocaine
| hemodynamically unstable: cardioversion
44
treatment for paroxysmal noctural dyspnea
acute: nitroglycerin
chronic: furosemide
45
drug that blocks ventricular remodeling s/p myocardial infarction
ACE-inhibitor
46
periumbilical systolic-diastolic bruit
renal artery stenosis
47
abdominal systolic bruit
more classically associated with AAA
48
blood pressure discrepancy in coarctation of the aorta
if coarctation is distal to the subclavian artery: upper extremity pressure is higher than lower extremity pressure
if coarctation is proximal to the subclavian artery: right arm pressure higher than left arm pressure
49
indications for class IA anti-arrhythmics
PSVT, Afib, Aflutter, Vtach
quinidine, procainamide
50
indications for class IB anti-arrhythmics
Vtach
lidocaine, tocainide
51
indications for class IC anti-arrhythmics
PSVT, Afib, Aflutter
flecainide, propafenone
52
indications for beta-blockers used as anti-arrhythmics
PVC, PSVT, Afib, Aflutter, Vtach
propanolol, esmolol, metoprolol
53
indications for K-channel blockers
Afib, Aflutter, Vtach (not bretylium)
amiodarone, sotalol, bretylium
54
indications for calcium channel blockers used as anti-arrhythmics
PSVT, MAT, Afib, Aflutter
verapamil, diltiazem
55
drug used in PSVT that activates K-channels and decreases intracellular cAMP
adenosine
56
first drug that should be administered when coronary artery event is suspected
aspirin to prevent platelet aggregation
57
situational syncome
autonomic dysregulation that may occur when an older man is micturating or coughing
58
treatment for prolonged QT
asymptomatic: propranolol
symptomatic: propranolol plus a DDD pacemaker (dual chamber)
59
treatment for pulseless electrical activity
initiate CPR followed by epinephrine or vasopressin
60
treament of asymptomatic young patient with no other health problems and CHADS2 score of 0
aspirin
61
CHADS2 score
```
congestive heart failure - 1
hypertension - 1
age > 75 - 1
diabetes mellitus - 1
stroke - 2
```
62
causes of pulsus paradoxus
cardiac tamponade, tension pneumothorax, and severe asthma
63
treatment of unstable patient with Afib
immediate cardioversion
64
treatment of stable patient with Afib
< 48 hours: cardioversion
| > 48 hours: 3-4 weeks of rate control and antiocogulation prior to cardioversion
65
mechanism of dipyramidole infused myocardial perfusion scanning
dipyramidole is a vasodilator, diseased vessels are already maximally dilated, so dipyramidole vasodilates non-disease vessels and draws even more blood away from diseased vessels
66
treatment for aortic regurgitation
afterload reduction with ACE-inhibitor or nifedipine, severe cases should undergo valve replacement
67
ranking of lifestyle modifications for high blood pressure
```
weight loss
DASH diet
dietary sodium
exercise
alcohol intake
```
smoking has little effect on hypertension but does contribute to heart disease
68
treatment of cocaine-induced STEMI
PTCA or thrombolysis
aspirin, nitrates appropriate, avoid beta-blockers which will allow unopposed alpha-activity and further vasoconstriction
69
pulsus parvus et tardus
decreased pulse amplitude and delayed pulse upstroke seen in aortic stenosis
70
mechanism of decreased preload in cardiac tamponade
pericardial fluid pressure exceeds ventricular pressure and inhibits ventricles from expanding and filling properly
71
drug of choice in patient with stable angina and hypertension
beta-blocker
72
mixed venous oxygen concentration in hypovolemic shock
decreased from increased oxygen extraction by hypoperfused tissue
73
mixed venous oxygen concentration in septic shock
normal from hyperdynamic circulation and improper distribution of the cardiac output
74
mechanism by which nitroglycerin relieves angina
dilaiton of veins decreases preload and stretching of myocardial muscle
it is actually unclear if nitroglycerin increases coronary blood flow in diseased patients although it performs this function in healthy coronary vessels, so this is not the major way angina is relieved
75
metabolic abnormalities found in hyperaldosteronism (conn's syndrome)
low renin, high aldosterone
| high sodium, low potassium, high bicarbonate (metabolic alkalosis)
76
pansystolic murmur at the apex with radiation to the axilla days to months after a myocardial infarction
ventricular aneurysm
papillary muscle rupture occurs 3-7 days after
77
normal right atrial pressure
4-6 mmHg
78
normal pulmonary artery pressure
25/15 mmHg
79
normal PCWP
6-12 mmHg
80
right atrial pressure > 10 mmHg
| pulmonary artery systolic pressure > 40 mmHg
diagnostic criteria for massive pulmonary embolism
81
unstable angina pharmacotherapy if no percutaneous intervention is planned
aspirin, clopidogrel
82
unstable angina pharmacotherapy if percutaneous intervention is planned
gp IIb/IIIa inhibitor
83
intranodal or bundle of His conduction problem
second degree mobitz I heart block
84
infranodal conduction problem
second degree mobitz II heart block
85
absence of conduction between atria and ventricles
third degree heart block
86
AV nodal reentry anomaly
PSVT
| treatment: adenosine, carotid massage, valsalva maneuver
87
AV reentry (not through the node, through accessory pathway)
wolff-parkinson-white
| treatment: amiodarone, procainamide
88
treatment of hemodynamically stable ventricular tachycardia
amiodarone
89
complication of esophageal dilation
esophageal rupture, penumomediastinum, and mediastinitis
90
causes of mediastinitis
iatraogenic procedure, boerrhave tear
91
biliary side effect of gastric bypass surgery
increased risk of gallstones
| treatment: ursodeoxycholic acid prophylactically for 6 months after surgery
92
somatic pain
sharp, localized pain
93
visceral pain
generalized, crampy pain
94
referred pain
visceral fibers enter spinal cord at the same location as somatic fibers and brain misinterprets visceral pain as somatic
95
wide fixed splitting of second heart sound
atrial septal defect
96
normal PCWP pressure
6-12 mmHg
97
normal right atrial pressure
4-6 mmHg
98
normal pulmonary artery pressure
does not exceed 25/15 mmHg
99
treatment of hemodynamically unstable PSVT
cardioversion or calcium channel blocker
100
treatment of stable PSVT
carotid massage or valsalva maneuver
| pharmacotherapy: beta-blocker or CCB
101
treatment for wolff-parkinson-white
amiodarone or procainamide
| NO adenosine
102
progressive PR lengthening until dropped QRS
second degree mobitz I heart block
103
randomly skipped QRS without changes in PR interval
second degree mobitz II
104
when is pacemaker indicated in heart bock
second degree mobitz II and third degree
| only indicated in mobitz I if there is symptomatic bradycardia present
105
several ectopic foci in the atria that discharge automatic impulses
usually asymptomatic
multifocal atrial tachycardia
| treatment: CCB or beta-blockers acutely, catheter ablation of surgery to eliminate abnormal pacemakers
106
causes of PVCs
hypoxia, abnormal serum electrolytes, hyperthyroidism, caffeine use
107
what do PVCs look like
early and wide QRS without preceding P waves
108
treatment of PVCs
none if patient is healthy, beta-blocker in patients with CAD
109
treatment for atrial flutter
rate control with CCB, beta-blockers, cardioversion if unable to be controlled with medication, and catheter ablation to remove ectopic focus
110
treatment for torsades de pointes
magnesium sulfate
111
treatment for stable ventricular tachycardia
procainamide or amiodarone
| amiodarone is drug of choice in patients with CHF
112
treatment for symptomatic bradycardia
atropine
113
most frequent physical exam finding of CHF
S3 sound
114
kerley B lines
increased marking of lung interlobular septa caused by pulmonary edema
115
indication for K-sparing diuretics in congestive heart failure
reduce cardiac hypertrophy caused by aldosterone
116
treatment for pericarditis
NSAIDs, colchicine
pericardiocentesis for large effusions
hemodialysis for uremic pericarditis
117
cardiac catherization shows equal pressure in all chambers
chronic constrictive pericarditis
118
causes of cardiac tamponade
pericarditis, chest trauma, LV rupture following MI, or dissecting aortic aneurysm
119
treatment for cardiac tamponade
immediate pericardiocentesis
120
harsh blowing holosystolic murmur radiating from apex to axilla
mitral regurgitation
121
widely split S2
mitral regurgitation
122
midsystolic click
mitral regurgitation
123
opening snap after S2
mitral stenosis
124
diastolic rumble
mitral stenosis
125
loud S1
mitral stenosis
126
widened pulse pressure
aortic regurgitation
127
bounding pulses
aortic regurgitation
128
diastolic decrescendo murmur
aortic regurgitation
129
late diastolic rumble
aortic regurgtation
130
crescendo-decrescendo systolic murmur
aortic stenosis
131
weak S2
aortic stenosis
132
dual stroke carotid pulse, systolic murmur, S4
hypertrophic obstructive cardiomyopathy
133
treatment for hypertrophic obstructive cardiomyopathy
beta-blockers, CCBs
| pacemaker or partial septal excision
134
treatment for mitral regurgitation
arterial vasodilators if symptomatic (nitroprusside)
| prophylactic antibiotics for increased infection risk
135
treatment for aortic regurgitation
decrease afterload with ACE-inhibitors, CCBs, or nitrates
136
treatment for aortic stenosis
beta-blockers
| diuretics to decrease preload
137
treatment for bacterial endocarditis
4-6 weeks IV antibitoics
beta-lactam plus an aminoglycoside
antibiotic prophylaxis before surgery or dental work
138
heart sounds you may hear with hypertension
loud S2, possible S4
139
causes of thoracic aortic aneurysms
marfan's syndrome, ehlers-danlos, and syphilis
140
most common location of aortic aneurysm
abdominal below the renal arteries
141
anti-hypertensive used in migraine headaches
beta-blockers
142
aortic dissection: stanford A v. stanford B
stanford A: ascending aorta, requires emergency surgery
| stanford B: distal to left subclavian, treat medically with nitroprusside, beta-blockers
143
wide fixed split S2, systolic ejection murmur at upper left sternal border
atrial septal defect
144
loud pumonic S2, systolic thrill
ventricular septal defect
145
loud S2, bounding pulses at birth
patent ductus arteriosus
| accompanied by a "machinery" murmur
146
risk factors for transposition of the great vessels
diabetic mother
| apert's syndrome, down syndrome, cri-du-chat, trisomy 13, trisomy 18
147
cardiac pathologies with "boot-shaped" heart on imaging
hypertrophic obstructive cardiomyopathy
tetralogy of fallot
persistent truncus arteriosus
148
treatment for tetralogy of fallot
prostaglandin E to maintain PDA, propranolol, morphine, knee-to-chest positioning during cyanotic episodes
149
treatment of mediastinitis
surgical debridement and prolonged antibiotic therapy
150
prophylactic treatment for long QT syndrome
propranolol
