cardiovascular health and cancer Flashcards

(192 cards)

1
Q

first and second leading causes of death in the US

A

CVD and cancer

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2
Q

diseases that affect the heart and blood vessels

A

CVD

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3
Q

cardiomyopathy

A

weakness of heart muscle

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4
Q

myocardial infarction

A

heart attack

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5
Q

angina pectoris

A

chest pain

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6
Q

stroke

A

blockage or rupture of vessels to the brain

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7
Q

leading cause of death in the US

A

CVD

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8
Q

___ deaths each day from CVD

A

2300

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9
Q

CVD risk is related to

A

lifestyle factors

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10
Q

components of cardiovascular system

A

heart, blood vessels

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11
Q

purpose of cardiovascular system

A

transport blood throughout body

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12
Q

cardiorespiratory system

A

CV + lungs

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13
Q

heart: ___ chamber

A

4

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14
Q

two circulatory systems in heart

A

pulmonary, systemic

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15
Q

pulmonary circulation

A

right side of the heart pumps oxygen-poor blood to lungs

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16
Q

systemic circulation

A

left side of heart pumps oxygen-rich blood to organs and tissues

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17
Q

path of blood flow from body hack to heart

A

superior/inferior vena cava
right atrium
right ventricle
pulmonary arteries to lungs
pulmonary veins to L atrium
mitral valve to L ventricle
aortic valve to aorta

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18
Q

largest artery in the body

A

aorta

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19
Q

aorta

A

distribute blood to rest of the body

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20
Q

each heartbeat has two actions controlled by

A

electrical and nerve impulses

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21
Q

2 actions of each heart beat

A

systole, diastole

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22
Q

systole

A

contraction to pump out blood

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23
Q

diastole

A

relaxation to fill with blood, atrial contraction to fill ventricles

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24
Q

blood pressure

A

force exerted by the blood on the walls of the blood vessels

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25
BP reported as
systolic pressure over diastolic pressure
26
veins
blood to heart
27
arteries
blood away from heart
28
thick elastic walls that expand and relax with the volume of blood
arteries
29
smallest arteries
capillaries
30
coronary arteries
two large vessels, supply blood to heart
31
main forms of CVD
o Atherosclerosis o CHD, CAD o Heart attack o Stroke o PAD o Congestive heart failure o Congenital heart disease o Rheumatic heart disease o Heart valve disorder
32
major risk factor and form of CVD
HTN
33
thickening and hardening of arteries
atherosclerosis
34
when cells that line the arteries become damaged the body response results in
inflammation and changes in arterial lining
35
___, ___, ___ cause a bulge in artery walls
LDL, platelets, other cell build up
36
atherosclerosis: as plaque accumulate, arteries
lose elasticity, restricting blood flow, and making the artery vulnerable to blockage by blood clots
37
atherosclerosis risk factors
tobacco use physical inactivity high cholesterol high BP diabetes
38
CVD related to atherosclerosis
CHD, stroke, PAD
39
CHD
coronary arteries are susceptible to plaque build up
40
stroke
blockage of cerebral artery to brain
41
PAD
blockage of artery in limb
42
chronic disease process resulting in damage to heart tissue from lack of oxygenated blood
myocardial infarction
43
symptoms and warning signs of myocardial infarctions
 Chest pain or pressure  Arm, neck, jaw pain  Difficulty breathing  Excessive sweating  Nausea and vomiting  Loss of consciousnes
44
before a heart attack, other symptoms and conditions can appear
angina, arrhythmias
45
angina
narrowing of arteries, stressed heart cannot receive enough oxygen, result in chest pain
46
angina relieved by
rest, nitroglycerin
47
arrhythmias
electrical conduction system disrupted
48
ventricular fibrillation
sudden cardiac death
49
treatment of arrhythmia
cardiac defibrillation AED
50
helping someone during heart attack
know warning signs act quickly aspirin CPR if no pulse
51
aspirin and heart attack
has immediate anti clotting effect
52
detecting heart disease
stress test- ECG/EKG echocardiogram CT MRI angiogram
53
angiogram
dye and x-ray
54
treating heart disease
o Balloon angioplasty o Statin, cholesterol-lowering medication o Aspirin o Other prescription drugs o Coronary bypass surgery o Diet and exercise change
55
cerebrovascular accident
stroke blockage in blood supply to the brain
56
blockage of blood vessel in brain, potentially treatable with clot-busting drugs
ischemic stroke
57
brain tissue dies when blood flow is blocked
ischemic stroke
58
87% of strokes
ischemic
59
types of ischemic stroke
thrombotic, embolic
60
thrombotic stroke
thrombus due to narrowed artery clots from where an artery has been narrowed
61
thrombotic usually due to
formation of fatty deposits that build up and reduce blood flow or to other artery conditions
62
embolic stroke
embolus becomes wedged n cerebral artery
63
25% of embolic strokes are related to
atrial fibrillation
64
13% of strokes
hemorrhagic
65
caused by ruptured blood vessels followed by blood leaking into tissue
hemorrhagic stroke
66
hemorrhagic or ischemic stroke more serious
hemorrhagic
67
types of hemorrhagic stroke
intracerebral, subarachnoid
68
intracerebral stroke
within the brain bleed from blood vessel in brain often caused by high BP
69
subarachnoid stroke
on brain surface bleed into the space between the brain and skull
70
subarachnoid stroke develops most often from
aneurysm
71
aneurysm
blood filled pocket that bulges out from a weak spot in artery wall
72
effects of stroke
 Death  Paralysis  Walking disability  Speech impairment  Memory loss  Changes in behavior
73
recognizing a stroke
FAST facial paralysis arm weakness speech difficulty time to call 911
74
stroke treatment
transient ischemic attack (TIA) recognize possible TA CT for diagnosis medication rehab, lifestyle changes
75
atherosclerosis in the arteries of limbs causing limited or blocked blood flow
PAD
76
risk factors for PAD
diabetes, tobacco
77
symptoms of PAD
claudation rest pain
78
congestive heart failure known as
cardiomyopathy
79
heart cannot maintain its regular pumping rate and force fluids back up and collect in the lungs and other areas
congestive heart failure
80
pulmonary edema
fluid accumulates in lungs
81
management of congestive heart failure
 Reduce cardiac load  Eliminate excess fluid intake  Restrict salt intake  Medication that increases the strength of pumping acting  Diuretics to eliminate excess salt and water  Cardiac rehab
82
congenital heart defects
born with, ,malformation of heart or major blood vessels
83
hypertrophic cardiomyopathy
enlargement
84
common cause of death in athletes under 35 y/o
hypertrophic cardiomyopathy
85
rheumatic heart disease
untreated strep infection causes rheumatic fever which permanently damages the hear muscle and valves
86
leading cause of heart failure worldwide
rheumatic heart disease
87
heart valve disorder
valves fail to open fully or close completely impairing blood flow through the heart
88
mitral valve prolapses
billowing of the mitral valve during ventricular contraction
89
nearly 1 in 5 deaths can be attributed to
smoking
90
___ doubles risk of stroke
smoking
91
when smokers have heart attacks, they are ___ times more likely than nonsmokers to die
2-3
92
silent killer
high BP
93
normal BP
120/80
94
rate of HTN is highest among
African americans
95
HTN treatment
lifestyle changes, medication
96
excessive levels of cholesterol can
clog arteries
97
LDL cholesterol
bad shuttle cholesterol from liver to organs and tissues
98
LDL cholesterol can accumulate on artery walls and
be oxidized by free radicals
99
HDL cholesterol
shuttle unused cholesterol back to liver for recycling
100
HDL treatment
lifestyle, medication
101
for every 1% of an individual lowers their total blood cholesterol their risk of heart attack decreases by
2%
102
estimated ___ Americans are so sedentary that they are at risk for developing CVD
40-60 million
103
exercise reduces risk of CVD by
o Controlling BP and resting HR o Increasing HDL o Maintaining weight o Improving the health of blood vessels o Preventing or controlling diabetes
104
most common cause of death in adults with diabetes is
CVD
105
more risk factors of diabetes
obesity, elevated lipids, low HDL
106
metabolic syndrome
* Three or more factors * Large waistline * High triglyceride level * Low HLD * High BP * High fasting blood sugar
107
psychological and social affects on CVD
* Stress * Chronic hostility and anger * Depression * Anxiety * Social isolation * Low socioeconomic status * Alcohol and drugs contribute to serious cardiac problems
108
risk factors for CVD that cannot be changed
genetics, age, gender, ethnicity
109
normal BP
120/80
110
elevated BP
120-120/<80
111
HTN stage 1
130-139/80-89
112
HTN stage 2
>140/>90
113
protective behaviors (CVD)
o Heart healthy dietary pattern o Decreased saturated and trans-fat intake o Eat high fiber diet o Reduce sodium intake o Avoid excessive alcohol consumption o Eat foods rich in omega-3 fatty acids, plant stanols and sterols o Adequate folate, vitamin b6, b12 o Exercise regularly o Avoid tobacco products o Know and manage your BP o Know and manage your cholesterol levels o Develop effective ways to handle stress and anger
114
group of diseases characterized by abnormal, uncontrolled multiplication of cells which can ultimately cause death if left untreated
cancer
115
mass of tissue that serves no physiological purpose
tumor
116
benign tumor
mass of cells enclosed in a membrane that prevents penetration into other tissues
117
malignant tumor
synonymous with cancer invade surrounding structures, including blood vessels, the lymphatic system, and nerves
118
every case of cancer beings as a
change in cell that allows it to grow and divide when it should not
119
metastasis
spreading of cancer cells from one part of the body to another
120
cells break away from the primary tumor and invade surrounding tissues or travel through the blood and lymphatic system creating
second tumor, mestases
121
stage of cancer classified according to extent of cancer based on
size primary tumor whether the cancer has invaded nearby lymph nodes whether metastases are present
122
remission
signs and symptoms of cancer disappear; disease is under control
123
five year surveil rate for all cancer is
68%
124
men are more likely to die from cancer because
 Higher rates of tobacco use  Higher rates of alcohol use and abuse  Greater occupational exposure to carcinogens  Less use of preventative measures and less contact with health care providers
125
screening and self-examination have the potential to save an additional -___ lives per year
100,000
126
role of DNA in cancer
certain genes predispose some people to cancer specific genetic mutations have been associated with cancer
127
smoking is responsible for ___ of cancer deaths
1/3
128
foods contain biologically active compounds that can
promote or protect against cancer
129
protective foods against cancer
fiber, fruits and vegetables
130
anticancer agents known as
phytochemical
131
food increase risk for cancer
saturated fat, processed meat alcohol high temp cooking
132
saturated fat and processed meat and cancer
may contribute to certain cancers, including colon, stomach, prostate
133
5% of cancers in men and 11% of cancers can be attributed to
excess body weight
134
a higher body mass index at age 25 increases ones risk of
cancer later in life
135
how excess body fat can lead to cancer: fat cells affect
hormone levels, inflammation, many cellular processes
136
how excess body fat can lead to cancer: can raise levels of
estrogen, insulin, other hormones
137
natural carcinogens
UV rays
138
microbes
viruses, bacteria, parasites
139
15-20% of worlds cancers caused by
microbes
140
helicobacter pylori causes
stomach cancer
141
epstein-Barr virus (mononucleosis)- causes
hodgkin lymphoma, cancer of nasopharynx, some stomach cancers
142
human herpes virus 8 causes
Kaposi’s sarcoma and certain types of lymphoma
143
hepatitis B and C causes
as many as 8-% of all liver cancers
144
nitrosamines
nitrates and nitrates combined with dietary substances highly potent carcinogens
145
radiation
medical x rays radiostopes sunlight
146
detecting cancer
self monitoring, routine cancer checkups
147
diagnosing cancer
biopsy, MRI, CT, ultrasonography
148
treating cancer
surgery, chemo, radiation
149
cancer classified according to
types of cells that give rise to them
150
carcinomas
epithelial tissue that covers body surfaces
151
sarcomas
connective and fibrous tissues
152
lymphomas
lymph nodes
153
leukemias
blood forming cells, chiefly in bone marrow
154
most common classification of cancer
carcinomas
155
most common cause of cancer death in the US
lung
156
lung cancer risk factors
smoking
157
lung cancer treatment
depends on type and stage surgery, chemo, radiation
158
5 year survival rate of lung cancer
22%
159
colon and rectal cancer risk factors
age, heredity preexisting polyps lifestyle
160
vast majority of colon cancer are diagnosed after
45
161
may decrease risk of colon cancer
nonsterodial anti-inflammatory drugs
162
detection of colon cancer
regular screening beginning at age 45
163
treatment of colon cancer
surgery
164
5 year survival rate for colon cancer
91-72% early 65% overall
165
most common cancer in women
breast
166
risk factors of breast cancer
 Genetic  Early onset of menstruation  Late onset of menopause  Having no children or having the first after age 30  Current use of hormone replacement therapy  Obesity  Alcohol use  Estrogen is the common factor in many of these
167
detection of breast cancer
mammogram, ultrasonography
168
treatment and prevention of breast cancer
 Surgery  Monoclonal antibodies  Selective receptor modulators (SERMs)- block estrogen receptors
169
5 year survival rate breast cancer
99% before spread 90% all stages
170
most common cancer in men
prostate
171
prostate cancer risk factors
age, diet, lifestyle, genetic predisposition
172
prostate cancer detection
PSA test
173
prostate cancer treatment
varies on stage and age
174
5 year survival rate of prostate cancer
100%
175
cervical cancer
STI caused by HPV
176
cervical cancer increased risk
smoking, immunosuppression, prolonged use of oral contraceptives
177
cervical cancer screening
pap, hpv test
178
cervical cancer treatment
surgery, chemo, radiation
179
uterine cancer most often occurs after
55
180
uterine cancer risk factors
similar to breast cancer
181
uterine cancer treatment
hysterectomy
182
5 year survival rate for uterine cancer
85% white women, 63% black
183
ovarian cancer risk factors
age, genetics, higher number of ovulations
184
ovarian cancer treatment
surgical removal of ovaries, fallopian tubes, uterus
185
ovarian cancer 5 year survival rate
93% for localized 49% for all stages
186
skin cancer risk factors
 Exposure to UV radiation  Sunburns and suntans, especially in childhood  Fair skin  Depleted ozone  Moles  Spending time at high altitudes  Family history
187
types of skin cancer
basal cell carcinoma, squamous cell, melanoma
188
most dangerous form of skin cancer
melanoma
189
prevention of skin cancer
avoid long-term overexposure to sunlight protection from sun
190
detection and treatment of skin cancer
signs in skin lesions ABCDE
191
skin cancer ABCDE
asymmetry, border, color, diameter, evolution
192
5 year survival rate skin cancer
99% if tumor is localized, distant stage 30%