Cartilage Flashcards Preview

F16: Anatomy Test 3 > Cartilage > Flashcards

Flashcards in Cartilage Deck (20):
1

Two methods for growth in cartilage?

Appositional Growth & Interstitial Growth

2

Interstitial Growth

Growth by internal expansion; proliferation of chondrocytes and formation of isogenous groups

3

Appositional Growth

Growth by addition to existing surface; generation of new chondroblasts

4

Major two cells in cartilage?

Chondroblasts & chondrocytes

5

Extracellular Matrix makeup?

Makes up 95% of cartilage.

Rich in glycosaminoglycans & proteoglycans.

Allows for withstanding mechanical forces; very resilient

6

Three types of cartilage?

Hyaline Cartilage
Elastic Cartilage
Fibrocartilage

7

Hyaline Cartilage: ECM composition and perichondrium?

75% water, proteoglycans, hyaluronic acid, type II collagen

Perichondrium: present (with few exceptions)

8

Hyaline Cartilage: location?

Articulate surfaces, nose, larynx, tracheal rings, epiphyseal plates, fetal bone models

9

Hyaline Cartilage: appearence?

Dissection: Bluish white and translucent

Histo: matrix is generally basophilic; in routine staining, collagen fibers are indiscernible

10

Which type of cell can add extracellular matrix?

Both chondrocytes (interstitial growth) and chondroblasts (appositional growth).

11

Isogenous groups Indicate what in a histo slide?

Indicates interstitial growth.

12

Territorial matrix vs interterritorial matrix?

Territorial: heavy purple close to cells; more GAGs less collagen

Interterritorial: light purple/pink between cells; more collagen less GAGs

13

Elastic Cartilage: ECM composition and perichondrium?

Essentially the same as hyaline cartilage with the addition of elastic fibers

Perichondrium present

14

Elastic Cartilage: location?

Auricle, auditory canal, auditory tube, epiglottis

15

Elastic Cartilage: appearance?

Dissection: yellowish color

Histo: with special staining, elastic fibers are prominent between chondrocytes and lacunae

16

Special characteristics of Elastic cartilage in epiglottis?

With age, cartilage shrinks and is replaced with adipose cells.

17

Elastic vs hyaline cartilage?

More chondrocytes in elastic cartilage than hyaline.

However, less isogenous groups in elastic cartilage.

18

Fibrocartilage: ECM and perichondrium?

Type I collagen, less proteoglycans than other cartilages

Perichondrium: absent

19

Fibrocartilage: location and why?

Places with lots of pulling forces.

Good intermediate between dense connective tissue and cartilage.

Intervertebral discs, pubic symphysis, major tendon-bone anchorages

20

Fibrocartilage: appearance?

Histo: chondrocytes arranged in long rows separated by coarse collagen fibers; matrix is more acidophilic