CELL COUNT Flashcards
The total leukocyte count is the most frequently performed cell count on synovial fluid.
Red blood cell (RBC) counts are seldom requested.
Cell count
To prevent cellular disintegration, counts should be performed _____ or the specimen should be _____.
as soon as possible
refrigerated
Most frequently performed count
WBC count
Diluting fluid for WBC count
NSS with methylene blue, Hypotonic saline 0.3%), Saline with saponin
_____ can be used for synovial fluid counts; however, highly viscous fluid may ____ the apertures, and the presence of debris and tissue cells may ____ counts.
As described previously, incubating the fluid with hyaluronidase ____ specimen viscosity.
Automated cell counters
block
falsely increase
decreases
Polymorphonuclear leukocyte
Bacterial sepsis
Crystal induced inflammation
Neutrophil
Mononuclear leukocyte
Non-septic inflammation
Lymphocytes
Large mononuclear leukocyte, may be vacuolated
Normal
Viral infections
Macrophages
Similar to macrophage, but
may be multinucleated resembling a
mesothelial cell
Synovial lining cell
Neutrophil containing characteristic ingested “Round homogenous body”
Lupus erythematosus
LE cell
Vacuolated macrophage with ingested neutrophils
Reiter syndrome
Non-specific inflammation
Reiter cell
Neutrophil with dark cytoplasmic
granules containing immune complexes
Rheumatoidarthritis
Immunologic inflammation
RA cell (Ragocyte)
Large multinucleated cells
Osteoarthritis
Cartilage cells
Macroscopically resembles polished rice
Microscopically shows collagen and fibrin
They are fragments of degenerating
proliferative synovial cells or microinfarcted synovium
Tuberculosis, septic and rheumatoid
arthritis
Rice bodies
Refractile intracellular and extracellular globules stain with Sudan
Traumatic injury
Fat droplets
