cellular review Flashcards
serum osmolarity (concentration)
280-294
edema
accumulation of fluid interstitially (at expense of vascular system when occurs acutely)
cell membrane
Semi-permeable (H2O and electrolytes) except when injured
mediated transport
Transport mediated by secreted molecules (hormones, neurotransmitters, etc)
histamine and bradykinin
Released with injury
body fluids
intra and extracellular - contain electrolytes and non-electrolytes (glucose, CO2, urea, etc)
sodium pump
Repolarizes cell by moving Na back out of cell (inside is relatively negative) allowing K in
diffusion
Movement of solutes from greater concentration to less concentration
osmosis
Movement of water to greater concentration gradient
depolarization
results in cell contraction
hydrostatic pressure
Blood pressure against semi-permeable vascular walls - force causing fluids to move out
byproduct of anaerobic metabolism
lactic acid (sensed by chemoreceptors)
plasma oncotic/osmotic pressure
Exerts pull on fluid to keep it inside vascular systems
hypotonic
osmolarity less than 280
hypertonic
osmolarity greater 295
dehydrated
hyperosmolar (hemoconcentrated - dehydrated)
fluid overload
Hypo-osmolar state (hemodiluted)
lymphatic system prevents edema by
removing excess fluid from interstitial spaces and returning to vascular system via thoracic and right lymphatic ducts
osmoreceptors
respond to changes in serum osmolarity by increasing ADH and increasing thirst
chemoreceptors
responds to changes in pH, CO2, O2
sodium balance; water balance
sodium balance maintained by aldosterone (adrenal cortex); water balance maintained by ADH
causes of hyperventalation
decrease O2, increased pCO2, fever, pain, anxiety
metabolic acidosis
results from anerobic metabolism (hypoxia, acid production)
result of hypoventilation
Respiratory acidosis (increased pCO2)