cellular review Flashcards

1
Q

serum osmolarity (concentration)

A

280-294

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2
Q

edema

A

accumulation of fluid interstitially (at expense of vascular system when occurs acutely)

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3
Q

cell membrane

A

Semi-permeable (H2O and electrolytes) except when injured

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4
Q

mediated transport

A

Transport mediated by secreted molecules (hormones, neurotransmitters, etc)

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5
Q

histamine and bradykinin

A

Released with injury

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6
Q

body fluids

A

intra and extracellular - contain electrolytes and non-electrolytes (glucose, CO2, urea, etc)

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7
Q

sodium pump

A

Repolarizes cell by moving Na back out of cell (inside is relatively negative) allowing K in

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8
Q

diffusion

A

Movement of solutes from greater concentration to less concentration

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9
Q

osmosis

A

Movement of water to greater concentration gradient

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10
Q

depolarization

A

results in cell contraction

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11
Q

hydrostatic pressure

A

Blood pressure against semi-permeable vascular walls - force causing fluids to move out

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12
Q

byproduct of anaerobic metabolism

A

lactic acid (sensed by chemoreceptors)

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13
Q

plasma oncotic/osmotic pressure

A

Exerts pull on fluid to keep it inside vascular systems

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14
Q

hypotonic

A

osmolarity less than 280

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15
Q

hypertonic

A

osmolarity greater 295

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16
Q

dehydrated

A

hyperosmolar (hemoconcentrated - dehydrated)

17
Q

fluid overload

A

Hypo-osmolar state (hemodiluted)

18
Q

lymphatic system prevents edema by

A

removing excess fluid from interstitial spaces and returning to vascular system via thoracic and right lymphatic ducts

19
Q

osmoreceptors

A

respond to changes in serum osmolarity by increasing ADH and increasing thirst

20
Q

chemoreceptors

A

responds to changes in pH, CO2, O2

21
Q

sodium balance; water balance

A

sodium balance maintained by aldosterone (adrenal cortex); water balance maintained by ADH

22
Q

causes of hyperventalation

A

decrease O2, increased pCO2, fever, pain, anxiety

23
Q

metabolic acidosis

A

results from anerobic metabolism (hypoxia, acid production)

24
Q

result of hypoventilation

A

Respiratory acidosis (increased pCO2)

25
Q

response to cell injury

A

histamine and bradykinin causes 3rd spacing (increased capillary permeability and vasodilation)

26
Q

purpose of edema formation

A

Protection from foreign substances, allows for neutrophils, lymphocytes and macrophages at the site of injury

27
Q

response to increased serum osmolarity

A

Kidney reabsorption of water

28
Q

baroreceptors

A

Respond to drop in blood pressure by stimulating the SNS

29
Q

lungs and kidneys

A

Excrete or retain to maintain pH (lungs - CO2 and kidneys - H+ or HCO3)

30
Q

potassium; sodium

A

Major intracellular and extracellular ions