CH 15-1 Flashcards Preview

BIO 119-352 > CH 15-1 > Flashcards

Flashcards in CH 15-1 Deck (22):
1

normal microbiota
lacrimal apparatus
lysozyme (tears, sweat)
skin
sneezing
nonspecific
mucous membrane
acidic pH
innate

first line of defense

2

fever
blood cells
complement
inflammation
nonspecific
phagocytes
interferon
macrophages
innate

second line of defense

3

lymphocytes
adaptive
antibodies

third line of defense

4

The two types of blood cells and their basic function are: ___ & ____
- Where are they produced? in bone marrow
-Granulocytes & agranulocytes belong to which type? leukocytes
- Lymphocytes & monocytes belong to which type? leukocytes

1. erythrocytes (red blood cells): transport oxygen & carbon dioxide
2. leukocytes (white blood cells): defense against microbes

5

Decrease in ______ causes increased bleeding time in a patient.

platelets

6

_____ can kill bacteria through phagocytosis and use of extracellular traps (NETS.)

Neutrophils

7

______ attach to the surface of parasitic helminths and produce toxins that kill the parasite.

Eosinophils

8

Which phagocyte, an agranulocyte, becomes a macrophage when leaving the bloodstream? ____

Monocytes

9

___ are lymphocytes that secrete toxins to kill tumor and virally infected cells.

Natural Killer cells

10

Phagocytic cells associated with the epidermis are ___.

Dendritic cells

11

A white blood cell count that shows elevated levels of ___ probably indicates allergies in the patient.

Eosinophils

12

________ are the most numerous leukocyte and come early to site of inflammation.

Neutrophils

13

Agranulocytes that are involved in the adaptive immune system are _________.

B & T cells

14

A granulocyte called ________ secretes histamine as part of inflammation.

Basophils

15

______ are agranulocytes that are the largest phagocyte and can travel throughout the body.

Macrophages

16

Define APC (antigen presenting cells) and list the cells that play this role:

phagocytoses antigen, chops up & displays pieces on receptors on cell surface
Dendritic cells, Macrophages, B lymphocytes

17

TLRs are located in a phagocyte’s ___ and NODs are located in the phagocyte’s ___ . Both bind to ____, microbial structures such as peptidoglycan, Lipid A, and viral RNA and initiate a defensive response to the microbes.

membranes; cytoplasm; PAMPs

18

-affects hypothalamus
-increases erythrocyte production
-sign something is wrong
-increases phagocytosis and effect of interferon
-pyrogen
-inhibits growth of temperature sensitive microbes
-reduces iron to microbe

fever

19

-acute heals body
-vasodilation and increased permeability
-at late stage stem cells repair damaged tissue
-monocytes and macrophages
-diapedesis
-forms pus before repair of tissue
-chronic can cause disease
-redness, heat, edema & pain

inflammation

20

-when activated triggers inflammation
-Classical, alternative, or lectin pathways
-Membrane Attack Complexes that create holes in Gram (–) membranes

complement

21

-monocytes and macrophages
-antiviral proteins

interferons

22

-pyrogen
-reduces iron to microbe
-diapedesis
-monocytes and macrophages

blood components