ch 24 Flashcards

1
Q

Diarrhea that occurs as a complication of taking antimicrobial medications.

A

Antibiotic-Associated Diarrhea

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2
Q

Fluid produced by the liver that aids in the digestion and absorption of fats.

A

Bile

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3
Q

Causes dental caries (tooth decay).

A

Cariogenic

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4
Q

Scarring of the liver that interferes with normal liver function.

A

Cirrhosis

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5
Q

A serious form of diarrhea characterized by blood, pus, and mucus in the feces.

A

Dysentery

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6
Q

Acute inflammation of the stomach and intestines; the syndrome of nausea, vomiting, diarrhea, and abdominal pain.

A

Gastroenteritis

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7
Q

Inflammation of the gums.

A

Gingivitis

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8
Q

A severe condition characterized by red blood cell breakdown and kidney failure.

A

Hemolytic Uremic Syndrome (HUS)

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9
Q

Inflammation of the liver.

A

Hepatitis

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10
Q

Tiny extensions from the surfaces of cells such as those lining the intestinal villi; they increase the surface area of the mucosa.

A

Microvilli

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11
Q

A treatment used to replace fluid and electrolytes lost due to diarrheal disease.

A

Oral Rehydration Therapy (ORT)

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12
Q

Short finger-like projections from the intestinal mucosa that slow the movement of food and increase the surface area of the intestinal lumen.

A

Villi

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13
Q

a route, administered or occurring elsewhere in the body than the mouth and alimentary canal: parenteral nutrition. Often contrasted with enteral.

A

parenteral route

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14
Q

an inflamed blister in or near the mouth, caused by infection with the herpes simplex virus.

A

cold sores

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15
Q

a single-celled microscopic animal of a group of phyla of the kingdom Protista, such as an amoeba, flagellate, ciliate, or protozoan.

A

protozoan

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16
Q

๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— Gastroenteritis, caused by many serotypes of salmonella bacterium, typically caused by animal fecal or poultry contaminating food or water.

A

salmonellosis

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17
Q

โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of salmonellosis.

The two species of ๐„๐ง๐ญ๐ž๐ซ๐จ๐›๐š๐œ๐ญ๐ž๐ซ๐ข๐š๐œ๐ž๐š๐ž, the S. enterica and S. bongori are both identified using ______ ______ method.

A

DNA sequence

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18
Q

โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of salmonellosis.

The ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ strains are subdivided based ______, found on the soma, flagella, and capsule.

A

antigens

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19
Q

โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of Salmonellosis.

In naming, due to the antigens, the serotype is often included and replaced by the ______ name.

Ex: ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ (๐’†๐’๐’•๐’†๐’“๐’Š๐’„๐’‚) ๐ƒ๐ฎ๐›๐ฅ๐ข๐ง

A

subspecies

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20
Q

Causative Agent of salmonellosis.

Most cases of salmonellosis are caused by food infected with ______, which often infects cattle and poultry, though other animals such as domestic cat and hamsters

A

๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’†๐’๐’•๐’†๐’“๐’Š๐’„๐’‚

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21
Q

โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’†๐’๐’•๐’†๐’“๐’Š๐’„๐’‚.

It is a Gram (-) rod and the most studied member of the ______ genus.

A

๐„๐ง๐ญ๐ž๐ซ๐จ๐›๐š๐œ๐ญ๐ž๐ซ๐ข๐š๐œ๐ž๐š๐žโ€‹

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22
Q

๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’†๐’๐’•๐’†๐’“๐’Š๐’„๐’‚.

It is caused by Ingestion of food contaminated by animal feces, especially _____.

A

poultry

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23
Q

๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’†๐’๐’•๐’†๐’“๐’Š๐’„๐’‚.

Medication increase susceptibility to _____, like ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’†๐’๐’•๐’†๐’“๐’Š๐’„๐’‚.

A

pathogens

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24
Q

๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of salmonellosis.

They vary depending on strains. The _____ strain causes bloody diarrhea, headaches, fever and *HUS.

A

๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š

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25
The ๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š strains are named ______ \_\_\_\_\_ \_\_\_\_\_\_:\_\_\_\_\_\_.
**E** **coli** **O157:H7**
26
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of ๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š. They cause _____ \_\_\_\_\_\_ ______ marked by anemia due to lysis of red blood cells and kidney failure, similar to \*cholera.
hemolytic uremic syndrome
27
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— infectious bacterial fever with an eruption of red spots on the chest and abdomen and severe intestinal irritation.
typhoid fever
28
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of typhoid fever is characterized by high fever, headache, and abdominal pain. Maybe followed by intestinal rupture causing internal _______ then shock, and death.
bleeding
29
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of typhoid fever. This member of Enterobacteriaceae grows both in the intestine and blood, it is a ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ serotype, Gram (-) and found in humans.
๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’•๐’š๐’‘๐’‰๐’Š
30
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’•๐’š๐’‘๐’‰๐’Š. The strain crosses ______ intestinal membrane and invades the bloodstream. This causes the life-threatening enteric-fever.
Mucous
31
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’•๐’š๐’‘๐’‰๐’Š. The strain also crosses the _______ intestinal
epithelium
32
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’•๐’š๐’‘๐’‰๐’Š. The strain is then taken up by **\_\_\_\_\_\_** cell where within it multiplies.
macrophages
33
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’•๐’š๐’‘๐’‰๐’Š. After invading M-cells, multiplying in macrophages it then travels throughout the body by this \_\_\_\_\_\_.
bloodstream
34
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’•๐’š๐’‘๐’‰๐’Š. If **\_\_\_\_\_\_** of patches are destroyed, then the intestine ruptures and hemorrhages.
Peyerโ€™s
35
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’•๐’š๐’‘๐’‰๐’Š. The source of infection is caused by **\_\_\_\_\_\_** of mammal.
Humans
36
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’•๐’š๐’‘๐’‰๐’Š. Transmission from person to person is by _____ method.
fecal-oral
37
โ„™๐•ฃ๐•–๐•ง๐•–๐•Ÿ๐•ฅ๐•š๐• ๐•Ÿ & ๐•‹๐•ฃ๐•–๐•’๐•ฅ๐•ž๐•–๐•Ÿ๐•ฅ of ๐‘บ๐’‚๐’๐’Ž๐’๐’๐’†๐’๐’๐’‚ ๐’•๐’š๐’‘๐’‰๐’Š. Although there are antimicrobial medications, the ______ typhoid vaccine helps prevent the typhoid fever.
Inactivated
38
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— both infectious and often fatal bacterial disease of the small intestine, typically contracted from infected water supplies, causing severe vomiting and diarrhea.
Cholera
39
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of Cholera. It causes a classical symptom of ______ when the **toxins** of the bacteria act on the **small intestinal epithelium**.
Watery-diarrhea
40
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of Cholera. The symptoms include diarrhea, vomiting, and cramps which have **\_\_\_\_\_\_** onset.
Abrupt
41
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of Cholera. In 1883, Robert Koch isolated _____ that is both alkali and salt tolerant, curved, Gram (-) rod.
๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’†
42
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— Rapid test for stool specimens from ๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’† revealed the ______ ๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’†.
toxicogenic
43
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’†. In general, the toxin causes secretion of chloride, electrolytes, and water out of the intestinal epithelium and into the \_\_\_\_\_. Without rehydration, shock happens.
lumen
44
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’†. It enters through by **\_\_\_\_\_\_** transmission of food or drink.
oral-fecal
45
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’†. They attach to the **\_\_\_\_\_\_** of cells in the small intestine.
epithelial
46
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’†. Inside the epithelial cells, the bacterium releases a toxin substance, causing the cells to continuously ______ chloride ions, then electrolytes and water.
secrete
47
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’†. The secreted liquids from the _____ cells travel to lumen intestinal region, causing watery diarrhea.
epithelial
48
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’†. After causing dehydration, the bacteria use the ______ route to exit the body with fluids.
Feces
49
โ„™๐•ฃ๐•–๐•ง๐•–๐•Ÿ๐•ฅ๐•š๐• ๐•Ÿ & ๐•‹๐•ฃ๐•–๐•’๐•ฅ๐•ž๐•–๐•Ÿ๐•ฅ of ๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’†. The main treatment consists of oral and **\_\_\_\_\_\_** therapy, which **rehydrates fluid and electrolytes**.
Intravenous
50
โ„™๐•ฃ๐•–๐•ง๐•–๐•Ÿ๐•ฅ๐•š๐• ๐•Ÿ & ๐•‹๐•ฃ๐•–๐•’๐•ฅ๐•ž๐•–๐•Ÿ๐•ฅ of ๐‘ฝ๐’Š๐’ƒ๐’“๐’Š๐’ ๐’„๐’‰๐’๐’๐’†๐’“๐’‚๐’†. Although a vaccine is available in some countries, handwashing and _______ water limit the disease.
purifying
51
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— infection by a bacterium that causes peptic ulcers in the stomach and the uppermost part of the small.
H. pylori infection
52
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of H. pylori infection. They are often asymptomatic, but ______ ulcers can cause abdominal pain, tenderness, and bleeding.
peptic
53
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of H. pylori infection. Infection may occur if **\_\_\_\_\_** is introduced into the layer of mucus that overlies the stomach epithelium.
tube
54
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of H. pylori infection. It is a microaerophilic bacterium that withstands stomach acid by producing urease.
๐‘ฏ๐’†๐’๐’Š๐’„๐’๐’ƒ๐’‚๐’„๐’•๐’†๐’“ ๐’‘๐’š๐’๐’๐’“๐’Š
55
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’๐’Š๐’„๐’๐’ƒ๐’‚๐’„๐’•๐’†๐’“ ๐’‘๐’š๐’๐’๐’“๐’Š. They thrive in stomach acidity by producing **\_\_\_\_\_\_,** an enzyme. They infect when burrowed within stomachโ€™s mucus coating.
urease
56
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’๐’Š๐’„๐’๐’ƒ๐’‚๐’„๐’•๐’†๐’“ ๐’‘๐’š๐’๐’๐’“๐’Š. **The \_\_\_\_\_\_** of the layer is damaged by bacterial products and inflammatory response. This may lead to peptic ulcers.
mucosal
57
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’๐’Š๐’„๐’๐’ƒ๐’‚๐’„๐’•๐’†๐’“ ๐’‘๐’š๐’๐’๐’“๐’Š. Most stomach cancers are due to H. pylori, but it causes cancer **\_\_\_\_\_\_**.
Rarely
58
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’๐’Š๐’„๐’๐’ƒ๐’‚๐’„๐’•๐’†๐’“ ๐’‘๐’š๐’๐’๐’“๐’Š. The most probable route is ______ transmission. Incidence do increases with age.
Oral-fecal
59
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— Gastroenteritis from the consumption of contaminated raw foods, raw vegetables and most notable, undercooked ground beef.
Escherichia coli Gastroenteritis
60
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of E. coli Gastroenteritis. Varies per strain, most are \_\_\_\_\_\_, and cause brief diarrhea.
harmless
61
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of E. coli Gastroenteritis. The _______ is a type of gram (-) rod, most strains ferment **lactose** which distinguishes them from the similar Shigella family.
๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š
62
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of Toxic E. coli Gastroenteritis. This ๐‘ฌ. ๐’„๐’๐’๐’Š strain produces types of Shiga toxins, and even make other toxins as well. Most identified in outbreaks.
๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ. ๐’„๐’๐’๐’Š
63
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of the ๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š. It causes severe diarrhea, stomach cramps, diarrhea, vomiting and ______ \_\_\_\_\_\_ \_\_\_\_\_\_.
HUS | (hemolytic uremic syndrome)
64
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š. The Shiga toxin strains are encoded by various prophages, a great example ______ conversion.
lysogenic
65
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š. It typically colonizes **\_\_\_\_\_\_\_ \_\_\_\_\_\_\_\_**, where it infects **effector proteins** that cause attaching and **effacing (A/E) lesions.**
large intestine
66
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š. The colonization damage results in diarrhea which becomes bloody due to the ______ \_\_\_\_\_ on the local blood vessels.
Shina Toxins
67
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š. About \_\_\_\_\_\_% develop the hemolytic uremic syndrome.
5-10
68
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š. They are easily spread by **\_\_\_\_\_\_ \_\_\_\_\_\_\_** transmission in addition to food-borne.
direct contact
69
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘บ๐’‰๐’Š๐’ˆ๐’‚ ๐’•๐’๐’™๐’Š๐’-๐’‘๐’“๐’๐’…๐’–๐’„๐’Š๐’๐’ˆ ๐‘ฌ๐’”๐’„๐’‰๐’†๐’“๐’Š๐’„๐’‰๐’Š๐’‚ ๐’„๐’๐’๐’Š. The initial source typically originates from untreated manure from **\_\_\_\_\_\_\_.**
cow
70
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— infection, that is caused by a form of viral hepatitis transmitted by fecal contamination of hands, food, or water.
Hepatitis-A-Infection
71
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of Hepatitis-A-Infection. It usually causing fever and jaundice with no _____ carriers. Its preventable by vaccination.
chronic
72
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of Hepatitis-A-Infection. The _______ is non-enveloped, ssRNA picornavirus family.
๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’” ๐‘จ ๐’—๐’Š๐’“๐’–๐’”
73
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’” ๐‘จ ๐’—๐’Š๐’“๐’–๐’”. Following ingestion, the virus reaches the \_\_\_\_\_\_\_, by an unknown route.
liver
74
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’” ๐‘จ ๐’—๐’Š๐’“๐’–๐’”. The liver is the only tissue damaged, this is the organ which _____ occurs.
replication
75
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’” ๐‘จ ๐’—๐’Š๐’“๐’–๐’”. The virus is released into the bile and eliminated by \_\_\_\_\_\_.
feces
76
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of HAV. It spreads by **the \_\_\_\_\_\_** route, mostly by fecal-contaminated hands, food, or water.
fecal-oral
77
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’” ๐‘จ ๐’—๐’Š๐’“๐’–๐’”. **The ______ group** is at high risk, also elderly at nursing homes, travelers and sexual active contact.
children
78
โ„™๐•ฃ๐•–๐•ง๐•–๐•Ÿ๐•ฅ๐•š๐• ๐•Ÿ & ๐•‹๐•ฃ๐•–๐•’๐•ฅ๐•ž๐•–๐•Ÿ๐•ฅ of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’” ๐‘จ ๐’—๐’Š๐’“๐’–๐’”. **The \_\_\_\_\_** vaccine prevents and immune globulin treatment.
Inactivated
79
๐”ธ ๐•‹๐•ช๐•ก๐•–-๐• ๐•— severe form of viral hepatitis transmitted in infected blood and semen, causing fever, debility, and jaundice.
Hepatitis B Infection
80
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of Hepatitis B Infection. Unlike Hep-A, it is more _____ and this-type of disease which leads to cirrhosis and cancer. It also can cross the placenta.
severe
81
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of Hepatitis B Infection. It is the \_\_\_\_\_\_\_, an **enveloped**, double-stranded DNA hepadnavirus.
๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ฉ-๐’—๐’Š๐’“๐’–๐’” | (HBV)
82
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ฉ-๐’—๐’Š๐’“๐’–๐’”. It first infects the _____ cell.
liver
83
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ฉ-๐’—๐’Š๐’“๐’–๐’”. In the liver, it uncaots and is transported to \_\_\_\_\_, a site of the cell.
nucleus
84
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ฉ-๐’—๐’Š๐’“๐’–๐’”. **RNA polymerase** transcribes the \_\_\_\_\_\_, generating **mRNA** and then **pgRNA**.
cccDNA
85
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ฉ-๐’—๐’Š๐’“๐’–๐’”. The mRNA is translated, producing the virally encoded proteins, then viral particles assemble and **HBV-encoded** -reverse-transcriptase packages into \_\_\_\_\_\_.
pgRNA
86
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ฉ-๐’—๐’Š๐’“๐’–๐’”. After assembling, the virus acquires **its \_\_\_\_\_** and it exits from the cell.
envelope
87
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ฉ-๐’—๐’Š๐’“๐’–๐’”. It spread by **\_\_\_\_\_\_\_** and or products containing, also by semen if sex.
blood
88
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— form of viral hepatitis transmitted in infected blood, possibly semen, causing chronic liver disease. It was formerly called non-A, non-B hepatitis.
Hepatitis C Infection
89
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of Hepatitis C Infection. Typically, few or no symptoms but the progression of **the \_\_\_\_\_\_** damage cause **cirrhosis** and **cancer** in chronic carriers.
Liver
90
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of Hepatitis C Infection. The ______ is an enveloped, single-stranded RNA flavivirus.
๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ช-๐’—๐’Š๐’“๐’–๐’”
91
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ช-๐’—๐’Š๐’“๐’–๐’”. Within the host cell, the viral genome is translated as a single _____ that is then cleaved by HCV protease into multiple proteins.
polyprotein
92
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ช-๐’—๐’Š๐’“๐’–๐’”. The virus infects the _____ and triggers inflammatory and immune responses.
liver
93
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ช-๐’—๐’Š๐’“๐’–๐’”. After that, the disease process starts and stopsโ€”at times the liver seems to return to normal, then weeks or months later shows marked \_\_\_\_\_\_.
inflammation
94
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘ฏ๐’†๐’‘๐’‚๐’•๐’Š๐’•๐’Š๐’”-๐‘ช-๐’—๐’Š๐’“๐’–๐’”. Most acquire the disease by sharing of syringes, others by tattoos, infected objects. Risk from blood transfusion is now extremely \_\_\_\_\_\_.
low
95
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— Gastroenteritis caused by a virus, most common in infants and children.
Rotaviral Gastroenteritis
96
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of Rotaviral Gastroenteritis. Vomiting, abdominal cramps, diarrhea, lasting 5 to _____ days
8
97
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of Rotaviral Gastroenteritis. Double-walled capsid virus, ds-segmented-RNA genome
๐‘น๐’๐’•๐’‚๐’—๐’Š๐’“๐’–๐’”
98
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘น๐’๐’•๐’‚๐’—๐’Š๐’“๐’–๐’”. It infects the epithelial cells that line the upper part of the _____ intestine.
small
99
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘น๐’๐’•๐’‚๐’—๐’Š๐’“๐’–๐’”. The infection causes epithelial cell death and decreased the production of _____ enzymes.
digestive
100
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘น๐’๐’•๐’‚๐’—๐’Š๐’“๐’–๐’”. The damaged lining _____ to absorb fluids, leading to watery diarrhea.
fails
101
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘น๐’๐’•๐’‚๐’—๐’Š๐’“๐’–๐’”. In addition, one of the viral proteins appears to function as an enterotoxin, causing fluid secretion in a manner somewhat similar to _____ toxin.
cholera
102
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘น๐’๐’•๐’‚๐’—๐’Š๐’“๐’–๐’”. Most common cause of viral gastroenteritis in _____ and children in the United States;
infants
103
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— viral gastroenteritis, most common originally called โ€œNorwalk viruses,โ€ The viruses are designated a category B bioterrorism agent because they spread easily.
Norovirus Gastroenteritis
104
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of Norovirus gastroenteritis. Typically causes nausea, vomiting, and watery diarrhea, but _____ in teenagers and adults.
severe
105
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of Norovirus gastroenteritis. The ______ is a non-enveloped, ssRNA virus.
๐‘ต๐’๐’“๐’๐’—๐’Š๐’“๐’–๐’”๐’†๐’”
106
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ต๐’๐’“๐’๐’—๐’Š๐’“๐’–๐’”๐’†๐’”. Noroviruses infect the epithelium of the upper small intestine, causing epithelial cell death and decreased the production of _____ enzymes.
digestive
107
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ต๐’๐’“๐’๐’—๐’Š๐’“๐’–๐’”๐’†๐’”. For reasons that are not understood, _____ to noroviruses is only short-term, lasting just several months.
immunity
108
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘ต๐’๐’“๐’๐’—๐’Š๐’“๐’–๐’”๐’†๐’”. Transmission of noroviruses is primarily by the _____ route
fecal-oral
109
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— intestinal infection caused by a parasite. It is a common cause of travelerโ€™s diarrhea.
Giardia
110
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of Giardia. They include \_\_\_\_\_, flatulence, nausea.
indigestion
111
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of Giardia. It is a flagellated pear-shaped protozoan with two nuclei.
๐‘ฎ๐’Š๐’‚๐’“๐’…๐’Š๐’‚ ๐’๐’‚๐’Ž๐’ƒ๐’๐’Š๐’‚
112
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฎ๐’Š๐’‚๐’“๐’…๐’Š๐’‚ ๐’๐’‚๐’Ž๐’ƒ๐’๐’Š๐’‚. the _____ survive in chlorinated water but can be removed by filtration.
cysts
113
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฎ๐’Š๐’‚๐’“๐’…๐’Š๐’‚ ๐’๐’‚๐’Ž๐’ƒ๐’๐’Š๐’‚. The Cysts enter the mouth, Ingested cysts survive \_\_\_\_\_, then to the lower small intestine.
stomach
114
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฎ๐’Š๐’‚๐’“๐’…๐’Š๐’‚ ๐’๐’‚๐’Ž๐’ƒ๐’๐’Š๐’‚. The Trophozoites are released from cysts in the small intestine, where dehydration in _____ intestine stimulates cyst development.
large
115
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ฎ๐’Š๐’‚๐’“๐’…๐’Š๐’‚ ๐’๐’‚๐’Ž๐’ƒ๐’๐’Š๐’‚. Mature cysts or trophozoites are eliminated in the _____ to contaminate soil, water, hands, and food.
feces
116
๐”ผ๐•ก๐•š๐••๐•–๐•ž๐•š๐• ๐•๐• ๐•˜๐•ช of ๐‘ฎ๐’Š๐’‚๐’“๐’…๐’Š๐’‚ ๐’๐’‚๐’Ž๐’ƒ๐’๐’Š๐’‚. Ingestion of focally _____ water; low infectious dose; person-to-person spread
contaminated
117
๐”ธ-๐•‹๐•ช๐•ก๐•–-๐• ๐•— diarrheal disease caused by microscopic parasites, that can live in the intestine of humans and animals and is passed in the stool of an infected person or animal.
Cryptosporidiosis
118
๐•Š๐•š๐•˜๐•Ÿ๐•ค & ๐•Š๐•ช๐•ž๐•ก๐•ฅ๐• ๐•ž๐•ค of Cryptosporidiosis. Fever, loss of \_\_\_\_\_, nausea, abdominal cramps, watery diarrhea
appetite
119
โ„‚๐•’๐•ฆ๐•ค๐•’๐•ฅ๐•š๐•ง๐•– ๐”ธ๐•˜๐•–๐•Ÿ๐•ฅ of Cryptosporidiosis. The _____ \_\_\_\_\_ is a protozoan parasite, apicomplexan.
๐‘ช๐’“๐’š๐’‘๐’•๐’๐’”๐’‘๐’๐’“๐’Š๐’…๐’Š๐’–๐’Ž ๐’‘๐’‚๐’“๐’—๐’–๐’Ž
120
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ช๐’“๐’š๐’‘๐’•๐’๐’”๐’‘๐’๐’“๐’Š๐’…๐’Š๐’–๐’Ž ๐’‘๐’‚๐’“๐’—๐’–๐’Ž. It is ______ due to animal models for the disease
unknown
121
โ„™๐•’๐•ฅ๐•™๐• ๐•๐• ๐•˜๐•ช of ๐‘ช๐’“๐’š๐’‘๐’•๐’๐’”๐’‘๐’๐’“๐’Š๐’…๐’Š๐’–๐’Ž ๐’‘๐’‚๐’“๐’—๐’–๐’Ž. Analysis of biopsies from infected patients confirms these protozoans are both present in the ______ epithelium.
intestinal
122