Ch 42: Immunology Flashcards Preview

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Flashcards in Ch 42: Immunology Deck (18):
1

Main functions of the immune system

Protects against infection and microbes
Isolates and removes non-microbial foreign substances

2

Pathogens

Invade because of an unlimited source of food/energy
Main objective is to get into blood circulation
Ex. parasites, bacteria, protists, fungi, viruses, etc.

3

Viruses

Non living pathogens

4

Neutrophils

Most abundant phagocytic cells
Engulfs pathogens and releases chemicals to kill the bacteria

5

Cytokines

Alarming chemicals
Send a siren throughout the body about an infection

6

Vasodilators

Cells that increase the size of the blood vessel
Allows more immune cells to get to the site quicker

7

Chemotaxins

Chemo attractants
Chemicals that tell immune cells exactly where to go

8

Mast cells

No direct contact with pathogen
Release histamine as an inflammation response
Raise alarm in the body and recruit other immune cells

9

B Lymphocytes

No direct contact with pathogen
Transform into plasma cells and release antibodies into circulation
Form memory cells

10

Memory cells

Cells that remember previous bacteria that have attacked the immune system
With increased contact, it takes less time to destroy them

11

Cytotoxic T cells

Release perforin and granzymes
Induce apoptosis

12

Histamine

Causes vasodilation
Increases blood flow to an infected area
Causes redness and swelling

13

Selectin

.

14

Margination

.

15

Integrin

.

16

Diapedesis

Phagocytic cells squeezing through the blood vessel

17

Opsonization

Binding then engulfing
Similar to endocytosis

18

Membrane Attack Complex (MAC)

Extracellular destruction
Cell embeds itself in the microbe membrane, forming pores
Ultimately leads to the formation of pores, which allows water to rush in