chap 5: Bone (bone remodeling and repair) (exam 2) Flashcards Preview

Organ histology (Exam 2) > chap 5: Bone (bone remodeling and repair) (exam 2) > Flashcards

Flashcards in chap 5: Bone (bone remodeling and repair) (exam 2) Deck (19)
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1
Q

in young people during remodeling development exceeds what

A

resorption

2
Q

in adults, after epiphyseal growth plate closure, what is in equilibrium?

A

development and resorption

3
Q

cancellous bone remodeling in adults is influenced by what

A

bone marrow cells

4
Q

compact bone remodeling in adults is influenced by what

A

systemic factors from endosteum and osteogenic periosteum

5
Q

What is the typical process of bone repair

A

fracture then bleeding, granulation tissue arises, osteoprogenitor cells become active, osteoprogenitor cells move into granulation tissue, blood vessels come back to area then bone develops

6
Q

bone fracture is damage to what?

A

tissue, matrix and much cell death

7
Q

After the initial break bleeding, clotting and the shut down of blood vessels to the area occur leading to what?

A

a decrease of O2 to the area and more cell death

8
Q

After the blood vessels shut down to the damaged area granulation tissue will develop causing which type of cells to migrate to the area

A

osteoprogenitor cells divide and come to the area

9
Q

Osteoprogenitor cells and osteoblasts can be found on the living edges and boney collar for the first what?

A

first 48 hours (stabilization)

10
Q

Osteoprogenitor cells will soon move into the granulation tissue below. With the decreased oxygen to that area the osteoprogenitor cells are forced to differentiate into what

A

chondrogenic cells

11
Q

once osteoprogenitor cells become chondrogenic cels they will turn into what? in order to secrete what?

A

turn into chondroblasts with secrete cartilage matrix

12
Q

the chondroblasts that secrete cartilage matrixes will form what?

A

forms fibrocartilagenous mix which will then form some chondrocytes

13
Q

after the fibrocartilagenous mix forms blood vessels will eventually what?

A

grow back to the injured area.

14
Q

this increased oxygen to the fibrocartilagenous mix causes the chondrocytes and blasts to do what?

A

causes them to die

15
Q

with the increased O2 to the fibrocartilagenous mix any chondrogenic cells will turn back into what

A

osteoprogenitor cells and then osteoblasts which produce one matrix

16
Q

Bone development is similar to what other type of development?

A

endochondral ossification

17
Q

diaphysis is what

A

shaft of bone

18
Q

epiphysis is what

A

ends of bone

19
Q

metaphysic means what

A

transition between the cartilage and bone