Chapter 4: Hyaline Cartilage (Exam 2) Flashcards Preview

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Flashcards in Chapter 4: Hyaline Cartilage (Exam 2) Deck (21)
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1
Q

Interstitial cartilage growth begins with what?

A

A grouping of rounded mesenchymal cells that can be called chondrogenic nodules

2
Q

chondrificaton within chondrogenic nodules involves what?

A

mesenchyme cells differentiate into chondroblasts

3
Q

What are two important factors affecting the differentiation of mesenchyme cells into chondroblasts?

A
  1. transcription factor being expressed (SOX-9)

2. forces exerted in the area

4
Q

during interstitial cartilage growth chondroblasts will secrete what?

A

will secrete matrix components when they are activated

5
Q

Matrix concentrates/sets up and chondroblasts do what?

A

they mature (differentiate) into chondrocytes once enough matrix has surrounded them

6
Q

What are two things chondrocytes will likely do?

A
  1. secrete matrix -> territorial matrix

2. divide if they have enough energy leading to isogenic groups

7
Q

cartilage development expands in what direction?

A

outward

8
Q

what is the stopping point of cartilage development?

A

chondrogenic perichondrium

9
Q

what does fibrous perichondrium develop from?

A

surrounding vascular mesenchyme tissue

10
Q

what is the cartilage growth mechanism?

A

a modified version of interstitial growth

11
Q

Where is interstitial growth found?

A
  1. articular cartilage

2. epiphyseal growth plates

12
Q

Is appositional cart growth faster or slower than interstitial?

A

appositional growth is much slower

13
Q

which type of cartilage growth, appositional or interstitial, more common?

A

appositional growth is more common

14
Q

appositional cartilage growth happened in whom?

A

fetuses, chidden regularly, and as a form of healing in adults

15
Q

the process of appositional growth originates within what layer?

A

the perichondrium

16
Q

chondrogenic cells and chondroblasts become what in appositional cartilage growth?

A

they become active

17
Q

how is it that chondrogenic cells become chondrocytes?

A

they differentiate into chondroblasts and secrete matrix all around themselves which will cause then to differentiate again into chondrocytes

18
Q

In appositional growth new chondroblasts can also develop from what?

A

fibroblasts in the fibrous perichondrium

19
Q

In appositional growth new chondrogenic perichondrium develops from what?

A

the previous fibrous perichondrium (all shifting outward)

20
Q

New fibrous perichondrium develops from what in appositional growth?

A

the surrounding CT

21
Q

Appositional growth functions to do what?

A

enlarge existing cartilage and in healing (which doesn’t heal very well)