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Flashcards in Chapter 10 Deck (23)
1

The goal of _________ is to destroy the infective agent without harming the host's cells.

antimicrobial chemotherapy

2

____ are natural substances released by bacteria and fungi into their environment

antibiotics

3

In nature, antibiotics act as a _____ to inhibiting other organisms that may cause them harm or steal nutrients/space.

defense mechanism

4

A drug must be able to be easy to administer and able to reach the infectious agent anywhere in the ______.

body

5

A drug must be able to be absolutely ____ to the infectious agent and non-toxic to the host.

toxic

6

A drug must be able to remain in the body as long as needed and be safely and easily ____ down and excreted.

broken

7

_____ is any chemical used in the treatment, relief, or prophylasxis of a disease.

chemotherapeutic drug

8

_____ is the use of a drug to prevent imminent infection of a person at risk.

prophylaxis

9

_____ is the use of chemotherapeutic drugs to control infection.

antimicrobial chemotherapy

10

_____ are all inclusive term for any antimicrobial drugs, regardless of its orgin.

antimicrobials

11

_____ are substances produced by the natural metabolic processes of some microorganisms that can inhibit or destroy other microorgansims.

antibiotics

12

_____ drugs produced entirely by chemical reactions._______ are drugs that are chemically modified in the laboratory after being isolated from natural sources.

semisynthetic drugssynthetic drugs

13

_______ antimicrobials effective against a limited array of microbial types for example, a drug effective mainly on gram-positive bacteria.

Narrow spectrum (limited spectrum)

14

Antimicrobials effective against a wide variety of microbial types - for example, a drug effective against both gram positive and gram negative bacteria.

broad spectrum - extended spectrum

15

Before antimicrobial therapy can begin, 3 factors must be
known:

1. the nature of the microorganism causing the infection
2. the degree of the microorganism’s susceptibility (or
sensitivity) to various drugs
3. the overall medical condition of the patient

16

Testing for Drug susceptibility is necessary for bacteria commonly showing ______.

resistance.

17

Bacteria that commonly showing resistance

staphylococcus species
Neisseria gonorrhoeae
Streptococcus pneumoniae
and many gram-negative enteric bacilli

18

Testing fro drug susceptibility is difficult and unnecessary for ___ or ____ infections.

fungal or protozoan

19

Testing for drug susceptibility is not as necessary if the patient is allergic to certain _____.

antibiotics

20

The Kirby Bauer ______ test begins with the surface of an agar plate is spread with bacteria. Called a _____.

disk-diffusion
bacterial lawn

21

Small disks containing a prepared amount of ______ are placed on the plate during a Kirby-Bauer test.

antibiotic

22

The _____ surrounding the discs in a Kirby Bauer test are measured and compared with a standard for each drug.

Zone of Inhibition or ZOI

23

Tube/broth dilution tests are more ____ and _____ than Kriby-Bauer test.

sensitive and quantitative