Chapter 13 Flashcards
(6 cards)
SEQ morgens experiment (Traits were associated with specific chromosomes)
Used fruit flies: Many offspring and Wild type
P Gen: X^w+ X^w+ by X^w Y
F1 Gen: All Offpsring had Red Eyes (w+)
F2 Gen: Same as 3:1 Ratio, but all white eye flies were males
Males can’t carry recessive
CC, HD sex chromosomes, sex linked traits (2)
Autosome
Sex Chromsome
Autosome
Not sex chromo
22 Pairs of HC
Homo-morphic (same shape)
Sex Chromosome
Determines Sex
Only one pair
Hetero-morphic (different shape)
Male = heterogametic
XY genotype
Female = homogametic
XX genotype
Linked Gene vs X Inactivation
X Linked Gene
Males: carry only one X = hemizygous hemi=half
All alleles on X are expressed
Female: carry two X = homozygous
Recessive alleles cannot be masked.
X Inactivation
Barr Body
1 X randomly inactivated during embryonic development
Inactive x condenses → Inactivation involves DNA methylation and histone proteins
If a female cat is heterozygous (XAXa)
In some cells: XA is active
In others, Xa is active
Violations of Independent Assortment
Linked Genes
Linked genes: are on the same chromosome
Linkage: genes being inherited together
Basically they don’t cross unlike in LOIA