Chapter 16 Flashcards
(67 cards)
hormone
- chemical messengers secreted by cells into extracellular fluid (endocrine system)
- effect cells thru out the body
- regulate metabolic functions (-) or (+)
half life
amount of time it takes for half of it to be broken down in blood thru out the body
up regulation
increase in some metabolic function
down regulation
decrease in some metabolic function
5 main effects a hormone can have on a cell
- Activate or deactivate enzymes
- Alter the plasma membrane
- Affect protein synthesis
- Affect secretory activity
- Affect mitosis
protein hormone action
- hormone can’t penetrate cell membrane
- it binds to a receptor in the membrane causing an enzymatic conversion of ATP > AMP
- stimulates a signal transduction pathway
steroid hormone action
- hormone passes through membrane due to its chemical nature
- it joins with an intracellular receptor then a DNA receptor protein which then activates or deactivates a gene
3 types of hormonal release
hormonal, humoral, and nueral
hormonal control
hormone from 1 endocrine gland stimulates/inhibits hormone release in another gland
humoral control
hormone stimulated by blood levels of ion or other compounds
neural control
responds to neural stimulus
pituitary gland
- “master gland” extends from hypothalamus
- like a pea on a stalk
- bi lobe: anterior and posterior
hormones produced by anterior pituitary gland
- TSH; GH
- FSH; LH
- ACTH; PRL
thyroid stimulating hormone (TSH)
stimulates thyroid
growth hormone (GH)
effects growth of body, bones
follicle stimulating (FSH) / luteinizing hormone (LH)
stimulate ovaries and testes
adrenocorticotropic hormone (ACTH)
stimulates adrenal glands
prolactin hormone (PRL)
stimulates milk production in mammary glands
dwarfism
lack of GH during childhood
gigantism
excess of GH during childhood
acromegaly
excess of GH during adulthood
Explain physiological relationship of the hypothalamus to the pituitary gland
hypothalamus makes GHRH and GHIH that trigger release of anterior pituitary hormones
2 hormones released by posterior pituitary
oxytocin and ADH
oxytocin
smooth muscle contraction in uterus