Chapter 16 Flashcards

(67 cards)

1
Q

hormone

A
  • chemical messengers secreted by cells into extracellular fluid (endocrine system)
  • effect cells thru out the body
  • regulate metabolic functions (-) or (+)
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2
Q

half life

A

amount of time it takes for half of it to be broken down in blood thru out the body

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3
Q

up regulation

A

increase in some metabolic function

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4
Q

down regulation

A

decrease in some metabolic function

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5
Q

5 main effects a hormone can have on a cell

A
  • Activate or deactivate enzymes
  • Alter the plasma membrane
  • Affect protein synthesis
  • Affect secretory activity
  • Affect mitosis
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6
Q

protein hormone action

A
  • hormone can’t penetrate cell membrane
  • it binds to a receptor in the membrane causing an enzymatic conversion of ATP > AMP
  • stimulates a signal transduction pathway
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7
Q

steroid hormone action

A
  • hormone passes through membrane due to its chemical nature

- it joins with an intracellular receptor then a DNA receptor protein which then activates or deactivates a gene

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8
Q

3 types of hormonal release

A

hormonal, humoral, and nueral

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9
Q

hormonal control

A

hormone from 1 endocrine gland stimulates/inhibits hormone release in another gland

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10
Q

humoral control

A

hormone stimulated by blood levels of ion or other compounds

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11
Q

neural control

A

responds to neural stimulus

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12
Q

pituitary gland

A
  • “master gland” extends from hypothalamus
  • like a pea on a stalk
  • bi lobe: anterior and posterior
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13
Q

hormones produced by anterior pituitary gland

A
  • TSH; GH
  • FSH; LH
  • ACTH; PRL
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14
Q

thyroid stimulating hormone (TSH)

A

stimulates thyroid

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15
Q

growth hormone (GH)

A

effects growth of body, bones

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16
Q

follicle stimulating (FSH) / luteinizing hormone (LH)

A

stimulate ovaries and testes

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17
Q

adrenocorticotropic hormone (ACTH)

A

stimulates adrenal glands

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18
Q

prolactin hormone (PRL)

A

stimulates milk production in mammary glands

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19
Q

dwarfism

A

lack of GH during childhood

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20
Q

gigantism

A

excess of GH during childhood

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21
Q

acromegaly

A

excess of GH during adulthood

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22
Q

Explain physiological relationship of the hypothalamus to the pituitary gland

A

hypothalamus makes GHRH and GHIH that trigger release of anterior pituitary hormones

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23
Q

2 hormones released by posterior pituitary

A

oxytocin and ADH

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24
Q

oxytocin

A

smooth muscle contraction in uterus

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25
ADH
(antidiuretic hormone) antagonist to diuretic; decrease in urine output
26
diuretics
compounds that increase urine production causing water loss; ex. caffeine and alcohol
27
diabetes insipidus
ADH deficiency due to damage to hypothalamus or to the posterior pituitary; causes polyuria and polydipsia
28
prolactinoma
- most common type of pituitary tumor | - leads to menstrual disturbances in females
29
thyroid gland hormones
thyroglobulin, calcitonin | -thyroxine and triiodothyronine
30
thyroglobulin
secreted by follicle cells; binds with iodine to produce T4 and T3
31
thyroxine and triiodothyronine
T4 and T3; stimulate metabolism
32
calcitonin
- secreted by parafollicular cells; antagonizes PTH | - stimulates Ca2+ uptake into the bone, removing it from the bloodstream
33
cretinism
hypothyroidism in kids
34
myxedema
hypothyroidism in adults
35
Grave’s disease
hyperthyroidism > irregular heartbeat, weight loss, protrusion of eyeballs (exopthalamus), nervousness
36
thyroid storm
- acute hyperthyroidism due to trauma to the thyroid, TH supplement abuse, or Grave’s disease patients who have stopped treatment - dangerous increase in HR, BP, body temp, sweating, vomiting, diarrhea
37
location and function of parathyroid gland
- behind thyroid gland; humoral control - secrete PTH; responds to low blood calcium - stimulates osteoclasts
38
osteitis cystica fibrosa
severe example of hyperparathyroidism > hypercalcemia > moth-eaten bones that break spontaneously
39
hypoparathyroidism
>low blood level of PTH; leads to hypocalcemia > hyperexcitablity of neurons >tetany > loss of sensation, muscle twitches, convulsions, respiratory paralysis, death
40
location of the adrenal glands
found on top of each kidney; pyramid-shaped
41
2 anatomical divisions of the adrenal glands
cortex and medula tissue
42
adrenal cortex
- synthesizes 24+ steroid hormones; outside layer | - hormones: aldosterone, cortisol, and adrogens
43
aldosterone
Kidneys: - increase blood level of sodium - decrease blood level of potassium
44
cortisol
Body cells: - assist body to resist stressors - mobilize fats for energy metabolism - stimulate protein catabolism
45
adrogens
- not significant in males - pubic and axillary hairs in women - source of estrogen after menopause
46
3 zones of cortex
zona glomerulosa, fasciculata, and reticularis
47
adrenal medula
middle layer; produces epinephrine and norepinephrine
48
epinephrine and norepinephrine
- increase heart rate and metabolic rate | - increase BP by promoting vasoconstriction
49
Cushing’s syndrome
too much cortisol > hyperglycemia, muscle and bone loss, high BP, edema due to water and salt retention
50
Addison’s disease
hyposecretion of aldosterone and cortisol > dehydration, low tolerance to stress
51
andrenogenital syndrome
- too much androgen secretion - in males > early maturation and aggressive sex drive - females > beard and masculination
52
pheochromocytoma
tumor of the adrenal medulla > hyperglycemia, fast HR, high BP, nervousness, sweating
53
hirsutism
excessive body hair growth due to excessive production of testosterone
54
diabetes mellitus type I
beta cells are destroyed and the person can’t make insulin (hyposecretion)
55
diabetes mellitus type II
beta cells stop producing insulin and/or the body’s cells become resistant to the insulin (hypoactivity)
56
polyuria
large urine output
57
polydipsia
excessive thirst
58
polyphagia
excessive hunger
59
gonads
produce steroid sex hormones - testes: testosterone - ovaries: estrogen and progesterone
60
main hormone released by the pineal gland
melatonin: increased secretion at night time (lack of natural light) contributes to making us sleepy
61
atrial natriuretic factor
- (ANF); secreted by specialized muscle cells in the heart - signal kidney to increase production of salty urine - increases urine output > decreases blood volume
62
enteroendocrine cells
- scattered cells in the GI tract in the mucosa | - secrete several hormones that aid in digestion in response to the presence of food
63
erythropoietin
increase RBC production in bone marrow
64
leptin
suppresses appetite
65
goiter
enlarged protruding thyroid; when myxedema results from lack of iodine
66
renin-angiotensin system
- BP/blood volume falls > kidneys release renin into blood - renin activates angiotensin: leads to vasoconstriction - increased angiotensin levels stimulate aldosterone release - aldosterone tells kidneys to hold sodium
67
location and function of the thyroid gland
wraps around anterior surface of the trachea, posterior to the laryns; bilobular, connected by an isthmus