Chapter 23: Microbial Diseases of the Cardiovascular System

Question 1

Septicemia

Answer 1

• persistant pathogens or their toxins enter the blood

Question 2

Sepsis

Answer 2

SIRIS

Question 3

Septic shock

Answer 3

final stage

Question 4

what is an example of septicemia

Answer 4

lymphangitis

Question 5

what is an example of spesis

Answer 5

pueperal sepsis

Question 6

pueperal sepsis is caused by

Answer 6

s. pyogenes (GAS)

Question 7

pueperal sepsis

Answer 7

• caused by s. pyogenes (GAS)
• abdominal cavity infection
• treatment: penicillin
• often not caught

Question 8

what is the treatment for pueperal sepsis

Answer 8

penicillin
- often not caught

Question 9

Rhematic fever

Answer 9

• “sequal to”
• GAS
• symptoms: fever, arthritis (nodules form), inflammation of the mitral valve 9valve replacement), chest pain, murmurs, death

Question 10

what bacteria is rhematic fever caused by

Answer 10

s pyogenes

Question 11

how does s pyogenes attach

Answer 11

m proteins

Question 12

gangreen produces what toxin

Answer 12

Alpha toxin

Question 13

alpha toxin

Answer 13

• produced by Gangreen
• breaks plasma membrane of blood vessels
• inhibits formation of lecithin

Question 14

gangreen causes

Answer 14

gun shot wounds, diabetics, improper abortion, fracture, deep wounds

Question 15

Gangreen

Answer 15

• produces alpha toxin
• causes necrosis
• symptoms: pain, fluid blood, blackening of skin (necrosis), gas formation (“pop and crackle noise) –> CO2, Hydrogen

Question 16

what bacteria causes gangreen

Answer 16

Clostridium perfringes

Question 17

progression of gangreen

Answer 17

Ischemia, necrosis, gangreen, gas gangreen

Question 18

Ischemia

Answer 18

loos of blood suppy to the tissue

Question 19

necrosis

Answer 19

dealth of the tissue

Question 20

what toxins does anthrax produce

Answer 20

• protective antigen
• lethal toxin
• edema toxin

Question 21

protective toxin

Answer 21

entery

Question 22

lethal toxin

Answer 22

evades phagocytosis

Question 23

edema toxin

Answer 23

swelling of entery

Question 24

Anthrax treatment

Answer 24

vaccine (not common)
- 6 doses + yearly

Question 25

anthrax was discovered by

Answer 25

robert koch

Question 26

what bacteria casues anthrax

Answer 26

bacillus anthracis - endospore - bioweapon - spread through soil

Question 27

what are the three manifestations of Anthrax

Answer 27

- GI - Pulmonary - skin/ cutaneous

Question 28

Gi manifestation of anthrax

Answer 28

- hemmoraging - 50% morality rate - caused by undercooked, contaminated meat

Question 29

Pulmonary manifestation of anthrax

Answer 29

- septicemia - 1005 mortality rate - inhalation of endospores

Question 30

Skin / Cutaneous manifestation of anthrax

Answer 30

- eschar - 20% mortality rate - treatment: pencillin, cipro

Question 31

how is anthrax treated

Answer 31

Ciprofloxacin

Question 32

Spotted fever is caused by which bacteria

Answer 32

Rikettsia rickettsi

Question 33

spotted fever caused a

Answer 33

macular rash - accompanied by fever and headache

Question 34

What micorbail doseases of the cardiovascular system are caused by protozoa

Answer 34

Malaria

Question 35

what are the hosts of malaria

Answer 35

mosqutios, humans

Question 36

life cycle of malaria in mosquitos

Answer 36

Sporozoite --> blood --> liver --> Meroites --> rupture --> blood RBC's (ring stage)--> burst --> more merozoids produced --> male and female gametes --> zygote --> Sporozoite

Question 37

life cycle of malaria in humans

Answer 37

Sporozoite --> blood --> liver --> Meroites --> rupture --> blood RBC's (ring stage)--> burst --> more merozoids produced --> released --> blood:RBC's

Question 38

HHSV -4 / EBV

Answer 38

abnormalities in B cells - growth + latency

Question 39

HHSV-4 / EBV causes (4)

Answer 39

- Birkitt's lymphoma - nasopharynx cancer - mono - chronic fatigue syndrome

Question 40

Birkitt;s lymphoma

Answer 40

- fast growing tumor of the jaw

Question 41

Mono

Answer 41

-"kissing disease" (transmitted via saliva - long incubation period (4-8weeks) - affects 1.5 million collage students per year - symptoms: fever, sore throat, fatigue, swollen lymph nodes, enlarged spleen

Question 42

chronic fatigue syndrome symptoms

Answer 42

- decrease muscle - decrease memory - increase titer of EBV

Question 43

HHSV-5 / Cytomegalovirus (CMV)

Answer 43

- inflammation of T cells - have inclusions (owl eyes) - transmitted: saliva, semen, vaginal fluid, placenta - causes retinitis (blindness)