Flashcards in Chapter 43: Anti-Histamine Deck (14)
Diphenhydramine MOA and clinical application
H1 receptor INVERSE AGONIST....motion sickness, anaphylaxis, parkinsonism, urticaria, insomnia, allergic rhinitis
Same as diphendrydraminate (benadryl)
First generation adverse effects?
actual my -dry-eye-isis (dry eyes)
sedation, dizziness, urinary retention/urgency
Pyrilamine - first generation, but what is main usage?
Promethazine clinical use and MOA
basically used to relieve preoperative anxiety and nausea
Hydroxyzine clinical use and MOA
*when something is so itchy you want to pour hydroxy on it*
ironically, can worsen your depression and suicidal thoughts
Cetirizine MOA and clinical app
Zyrtec is 2nd generation
allergic rhinits / urticaria
2nd generation - claritin
Which second generation H1 inverse agonist cannot be used concurrently with MAO inhibitors, severe hypertension and severe coronary artery disease?
(acriVASTine - VAST contraindications)
Allegra first gen
Levocabastine cannot be used in people with...
What drug would you give for vasomotor rhinits and what is the contraindication?
dont use with alchohol