Chapter 43: Anti-Histamine Flashcards Preview

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Flashcards in Chapter 43: Anti-Histamine Deck (14)
1

Diphenhydramine MOA and clinical application

H1 receptor INVERSE AGONIST....motion sickness, anaphylaxis, parkinsonism, urticaria, insomnia, allergic rhinitis

= benadryl

2

Dimenhydrinate

Same as diphendrydraminate (benadryl)

3

First generation adverse effects?

midriasis

actual my -dry-eye-isis (dry eyes)

dry mouth

sedation, dizziness, urinary retention/urgency

4

Pyrilamine - first generation, but what is main usage?

Insomnia

5

Promethazine clinical use and MOA

first generation

basically used to relieve preoperative anxiety and nausea

6

Hydroxyzine clinical use and MOA

pruritis

first generation

*when something is so itchy you want to pour hydroxy on it*

7

Doxepin

tricyclic antidepressant

ironically, can worsen your depression and suicidal thoughts

8

Cetirizine MOA and clinical app

Zyrtec is 2nd generation

allergic rhinits / urticaria

9

Loratadine MOA

2nd generation - claritin

10

Which second generation H1 inverse agonist cannot be used concurrently with MAO inhibitors, severe hypertension and severe coronary artery disease?

Acrivastine

(acriVASTine - VAST contraindications)

11

Fexofenadine MOA

Allegra first gen

12

Levocabastine cannot be used in people with...

contact lens

13

What drug would you give for vasomotor rhinits and what is the contraindication?

azelastine

dont use with alchohol

14

Olopatide is unique because it can be a ___ administration

topical nasal antihistamine

the nostrils look like Os...OOOOlopadine