Chapter 43: Tobacco Cessation Flashcards

(45 cards)

1
Q

Pack year smoking history

A

Cigarette packs/day x number of years

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2
Q

THE “5 A’S” MODEL FOR TREATING TOBACCO USE AND DEPENDENCE

A

Ask about tobacco use
Advise to quit
Assess readiness to quit
Assist in quit attempt
Arrange follow up

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3
Q

What are withdrawal symptoms associated with smoking cessation?

A

Anxiety, irritability, depression, insomnia, poor concentration, restlessness, increased appetite, and cravings

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4
Q

Which combination of strategies is more effective for smoking cessation?

A

Combination of counseling and medication

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5
Q

List the five nicotine replacement therapies (NRTs).

A
  • Patch
  • Gum
  • Lozenge
  • Inhaler
  • Nasal spray
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6
Q

What are the two non-nicotine drugs used in smoking cessation?

A
  • Bupropion
  • Varenicline
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7
Q

Combining a nicotine patch with what type of NRT is effective?

A

Short-acting NRT (e.g., gum) or varenicline

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8
Q

Which patient populations are mentioned as preferring behavioral counseling over drug treatment?

A
  • Pregnant women
  • Adolescents
  • Smokeless tobacco users (e.g., chewing tobacco)
  • ‘Light’ smokers (e.g., < 1 cigarette a day)
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9
Q

Fill in the blank: ______ is preferred for smoking cessation in pregnant women.

A

[Behavioral counseling]

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10
Q

What enzymes are primarily induced by non-nicotine chemicals in tobacco smoke?

A

CYP450 1A2

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11
Q

List some medications that can cause side effects due to supratherapeutic levels after quitting smoking.

A
  • Caffeine
  • Theophylline
  • Fluvoxamine
  • Olanzapine
  • Clozapine
  • R-isomer of warfarin

These medications may have altered metabolism in individuals who have recently quit smoking.

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12
Q

Who should not take estrogen-containing oral contraceptives?

A

Women ≥ 35 years of age who smoke

The risk of cardiovascular events increases with smoking and estrogen use.

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13
Q

What vaccinations should smokers aged 19 - 64 years receive?

A
  • Pneumococcal vaccine
  • Annual influenza vaccine
  • All age-appropriate vaccines
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14
Q

What is the brand name of the nicotine patch?

A

NicoDerm CQ

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15
Q

What is the initial dosing for nicotine replacement therapy based on?

A

The number of cigarettes smoked per day

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16
Q

What should be avoided in the immediate post-MI period when using nicotine products?

A

NRT (Nicotine Replacement Therapy)

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17
Q

What are common side effects of nicotine replacement therapy?

A

Insomnia, headache, dizziness, nervousness, dyspepsia

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18
Q

What should be done before using nicotine gum or lozenge?

A

Avoid acidic beverages/foods 15 minutes before or during use

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19
Q

True or False: The FDA prohibits the sale of nicotine products to individuals under 21 years of age.

20
Q

What specific warnings are associated with the use of the nicotine inhaler or nasal spray?

A

Avoid in asthma, COPD, and other chronic respiratory diseases

21
Q

What is a common side effect of the nicotine patch?

22
Q

What is the duration of treatment for nicotine patch dosing?

A

The nicotine patch dosing schedule lasts for 8-10 weeks.

23
Q

What is the dosing schedule for the nicotine patch if > 10 number of cigs per day?

A

21 mg/day for 6 weeks, then 14 mg/day for 2 weeks, then 7 mg/day for 2 weeks

24
Q

For nicotine gum/lozenge dosing, what is the starting dose if the first cigarette is smoked within 30 minutes of waking?

A

4 mg q1- 2h for 6 weeks

25
What is the mechanism of action for bupropion?
Blocks neuronal reuptake of dopamine and/or norepinephrine. This results in reduced cravings and withdrawal symptoms.
26
When should bupropion be started in relation to the quit date?
1-2 weeks before quit date
27
What is the dose of bupropion SR?
150 mg QAM for 3 days then 150 mg BID max: 300 mg/day
28
What is a major boxed warning associated with bupropion?
Increased risk of suicidal thinking and behavior in children, adolescents, and young adults
29
What are some contraindications for bupropion use?
* Seizure disorder * History of anorexia/bulimia * Concurrent use with MAO inhibitors, linezolid, or IV methylene blue * Abrupt discontinuation of alcohol or sedatives
30
What are common side effects of bupropion?
* Dry mouth * Insomnia * Tremors * Weight loss
31
What should be done to minimize insomnia when taking bupropion?
Take the 1st dose upon waking and the 2nd dose 8 hours after the 1st dose
32
What is varenicline?
A partial neuronal alpha-4 beta-2 nicotinic receptor agonist
33
When should varenicline be started?
One week before the quit date
34
What are some serious warnings associated with varenicline?
* Serious neuropsychiatric events
35
What are common side effects of varenicline?
* Nausea (~30%, dose-dependent) * Insomnia * Vivid dreams * Headache
36
What should be done if nausea occurs with varenicline?
Take after eating with a full glass of water; can reduce dose if needed
37
What combination is more effective than the nicotine patch alone?
Nicotine patch + gum, lozenge, or bupropion
38
How does varenicline's efficacy compare to bupropion?
Varenicline is more effective than bupropion
39
What should be avoided in patients with dentures?
Gum
40
What should be avoided in patients with asthma or COPD?
Inhaler, nasal spray
41
What should be avoided in patients with a history of seizures?
Bupropion and varenicline
42
What is a key counseling point for nicotine patch administration?
Remove a new patch from the pouch at the start of each day
43
How long should a nicotine patch be worn?
24 hours
44
What should be done if vivid dreams or trouble sleeping occur with a nicotine patch?
Remove the patch prior to bedtime
45
What can help with minor skin irritation from a nicotine patch?
Topical hydrocortisone