Chapter 45 - Neurologic complications Flashcards
Blood supply to the nerve
1) vasa nervorum
2) diffusion
Time threshold for irreversible nerve injury
6-10 hours (in animals)
Ischemic monomelic neuropathy
No axonal degeneration and demyelination
Altered flow through vasa nervorum cause acute conduction block
persistence –> distal axonal infarction
Chronic ischemic neuropathy vs acute pathology
pathogenesis appears to be the same
Neurapraxia definition
transient nerve dysfunction
Common causes of unilateral neuropathy
1) entrapment
2) trauma
3) ischemia
4) vasculitis
Common causes of bilateral neuropathy
1) metabolic (diabetes, uremia)
2) toxic (alcohol, drugs, metal)
3) connective tissue disease, vasculitis
4) deficiency (vitamin)
5) inflammatory
6) monoclonal gammopathies
7) HIV infection
Ischemic neuropathy in lower extremity presentation
1) unilateral sensory loss - stocking distribution; especially vibration
2) ankle weakness
3) depressed ankle reflex
Distal latency and velocity of conduction in ischemic neuropathy vs diabetic and uremic neuropathy
well preserved in ischemic neuropathy
reduced in a symmetrical bilateral way in diabetic/uremic neuropathy
Sensory nerve in ischemic neuropathy
Absent sensory potential amplitude but velocity is normal
First line treatment for pain control - ischemic neuropathy
1) TCA
2) SSRI
3) Calcium channel alpha-2 delta (Gabapentin, pregabalin)
Peripheral nerves matched to nerve roots
Axillary - C5, C6 Musculocutaneous nerve - C5, C6 Median nerve C5-T1 Radial C5-C8 Ulnar C8, T1
Nerve injury during axillary artery exposure
Cords of the brachial plexus
Nerve injury during brachial artery exposure
Median nerve
Ulnar nerve
Nerve injury from positioning
Ulnar nerve
Nerve injury during basilic vein exposure
ulnar nerve
rate of Nerve injury during brachial artery catheterization
0.2-1.4%
HD access causing IMN most likely with what type of AVF
Brachial artery use
Consequence of axillary nerve injury
weakness of shoulder abduction
sensory deficit over deltoid
Median nerve injury consequences
sensory deficit in D1-3 and radial aspect of D4
weakness in thenar muscle
weakness on flexor of digit and wrist
Consequences of ulnar nerve injury
numbness in D5 and ulnar aspect of D4
weakness of hypothenar muscle
weakness in abduction and adduction of all digits and flexion of D4, D5
Consequences of injury to radial nerve
weakness of wrist and finger extension
Lumbosacral nerves and correlated nerve roots
Lateral femoral cutaneous nerve L2-L3 Femoral nerve L2-L4 Obturator nerve L2-L4 Posterior femoral cutaneous nerve S1-S3 Sciatic nerve L4-S3 Common peroneal L4-S2 Tibial nerve L4-S3
Blood supply to lumbosacral plexus
5 sets of paired lumbar arteries from abdominal aorta, deep circumflex iliac and iliolumbar and gluteal branches of IIA