Chapter 47: Development Flashcards

1
Q

model organisms

A

organisms used for developmental research; easily available or bred

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2
Q

fertilization

A

union of sperm and egg

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3
Q

vitelline layer

A

extracellular matrix of unfertilized egg

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4
Q

jelly coat

A

coat of unfertilized egg that protects egg and attracts sperm

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5
Q

acrosomal reaction

A

reaction triggered by contact of egg with sperm

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6
Q

acrosome

A

vesicle at sperm tip with hydrolytic enzymes break down jelly

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7
Q

acrosomal process

A

structure w/ proteins that bind receptors on eggs

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8
Q

depolarization

A

fusion leads to change in membrane potential

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9
Q

polyspermy

A

multiple sperm fertilizing an egg; blocked by depolarization and fertilization envelope

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10
Q

cortical reaction

A

initiated by fusion of egg and sperm; vesicles in cortex fuse with plasma membrane, leads to fertilization envelope

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11
Q

fertilization envelope

A

slower response to block polyspermy; separates vitelline layer from plasma membrane and breaks up receptors so more sperm don’t bind

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12
Q

activation of the egg

A

follows cortical reaction; increased respiration and protein synthesis, sperm nucleus fuses with egg nucleus

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13
Q

cleavage

A

earliest division, rapid; cell division without growth

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14
Q

blastomeres

A

individual cells formed by cleavage

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15
Q

blastula

A

hollow ball of cells with a blastocoel

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16
Q

blastocoel

A

internal cavity of blastomeres

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17
Q

cytoplasmic determinants

A

proteins, mRNA, etc. in specific places that code for body polarity

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18
Q

yolk

A

stored nutrients; help determine first cleavage

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19
Q

vegetal pole

A

pole in which yolk is concentrated

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20
Q

animal pole

A

pole opposite the vegetal pole

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21
Q

animal-vegetal axis

A

anterior-posterior axis

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22
Q

light gray crescent

A

area opposite sperm entry; sets polarity at fertilization

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23
Q

shape of blastula

A

influenced by presence of yolk; 8 cells, unequal, offset by yolk

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24
Q

gastrulation

A

the ball of cells turns into a structure with tissue layers and a gut

25
gastrula
early gut
26
3 germ layers
ectoderm, endoderm, mesoderm
27
vegetal plate
future endoderm; invaginates and becomes archenteron
28
archenteron
open cavity in the gastrula; blastopore is the opening and future anus in deuterostomes
29
ectoderm
skin, nervous system, and other
30
mesoderm
skeleton, muscles, circulatory system, excretory system, lining of body cavity, and others
31
endoderm
lining of digestive tract, respiratory system, and others
32
early organogenesis
cells differentiate to form organs; notochord, neural plate, neural tube, neural crest cells, somites
33
cell differentiation and morphogenesis
continuation of organogenesis that leads to adult organs
34
blastoderm
a disk that forms as two layers of cells on a large yolk
35
hypoblast
cell layer of blastoderm on yolk
36
epiblast
cell layer of blastoderm on top
37
primitive streak
gastrulation by migration of epiblast cells toward yolk
38
extraembryonic membranes
chorion, amnion, yolk sacs, allantois
39
chorion
extraembryonic membrane that functions in gas exchange
40
amnion
extraembryonic membrane that encloses embryo in fluid
41
yolk sac
extraembryonic membrane that surrounds yolk
42
allantois
extraembryonic membrane that sequesters waste products
43
blastocyst
mammalian blastula consists of trophoblast and inner mass cells
44
trophoblast
outer epithelium that initiates implantation; secretes enzymes to break down endometrium;
45
inner mass cells
part that will become the embryo; form epiblast and hypoblast
46
placenta
derived from trophoblast, mesoderm from the epiblast, and endometrial tissue; forms from embryonic and maternal tissue to exchange, nutrients, gases, wastes, etc.
47
fetus
late embryo, after about 8 weeks in humans
48
animals cells change shape
use of cytoskeleton; microtubules elongate and microfilaments narrow the apex
49
cell adhesion molecules
used by cells to form stable tissues; glycoproteins on cell surfaces
50
migration of cells
mediated by extracellular matrix
51
cells differentiate
division of cells into different functions with specific body axes, gene expression, etc.; begins with cytoplasmic determinants
52
induction
changes in gene expression based upon cell-cell interaction; pattern formation and positional information
53
fate map
map of cell differentiation
54
developmental potential
ability of a cell to become different types of cells; lost as cell lines develop
55
totipotent
ability of a cell to differentiate into any function
56
limb buds
beginning of limbs, covered in a layer of ectoderm
57
apical ectodermal ridge (AER)
tip of bud; secretes growth factor that extends limb bud
58
zone of polarizing activity (ZPA)
a group of cells in the posterior limb bud that controls the anteroposterior (AP) patterning of the limb