Chemistry Flashcards

(53 cards)

1
Q

What is the structure of ketamine

A

A benzene ring with the chloride atom in o-position, connected to a cyclohexane ring with a =O in 2nd position and an NHCH3 in the connecting bond b/with the 2 rings

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2
Q

Structure of propranolol

A

NH-CH(CH3)²

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3
Q

By using what compound is the reduction of the intermediate done, in the synthesis of Phenylephrine?

A

NaBH4

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4
Q

By using what compound is the red of the intermediate done in the synthesis of salbutamol?

A

LiAlH4

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5
Q

By using what compound is the red of the intermediate done in the synthesis of salbutamol?

A

LiAlH4

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6
Q

Starting materials of ketamine

A

O-chloro benzonitrile and cyclopentyl MgBr

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7
Q

Synthesis of Diazepam

A

Refer the book

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8
Q

Starting material in the synthesis of carbamazepine

A

Alpha nitro toluene

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9
Q

Synthesis of ethosuximide

A

Refer the book

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10
Q

Structure of purine

A

Pyrimidine (benzene with N in C-2 and C-4) fused with Imidazole (cyclopentane with N in C1 and C3)

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11
Q

Structure of coumarin

A

Benzene fused with furan (double bond between C1 and C2) with =O in C3

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12
Q

Structure of acetone

A

CH3-C (double bond O)-CH3

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13
Q

Structure of pyrimidine

A

Benzene with N in C2 and C4

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14
Q

Synthesis of Acetazolamide

A

Refer the notebook

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15
Q

Synthesis of Dibucaine

A

Refer the notebook

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16
Q

Synthesis of Disopyramide

A

Refer the notebook

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17
Q

Synthesis of Methotrexate

A

Refer the notebook

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18
Q

Synthesis of Warfarin

A

Refer the notebook

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19
Q

Synthesis of Chlorthiazide

A

Refer notebook

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20
Q

Synthesis of Furosemide

A

Refer the notebook

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21
Q

What is the structure of Pteridine?

A

Pyrimidine (benzene with N in ortho and para position) fused with Pyrizine (benzene with N in C1 and C4)

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22
Q

Synthesis of Dapsone

A

Refer the notebook

23
Q

Synthesis of Para-amino salicylic acid

A

Refer the notebook

24
Q

What are the starting materials for the synthesis of Para amino salicylic acid?

A

m-Nitro Phenol or 2-Amino Benzoic acid

25
Structure of Tolnaftate
Beta-naphthol - (C=S) - NH(CH3) - m - toluene
26
Structure of Di-ethyl carbamazine citrate
H3C - N (cyclohexane) N - (C=O) - N (C2H5)²
27
Synthesis of Diethylcarbamazine citrate
Refer the notebook
28
What is the decreasing order of alcohols, in terms of their speed of reaction in SN1/SN2 and E1/E2?
For SN1 and E1, 3>2>1 For SN2 and E2, 1>2>3
29
What type of reaction is SN1 and E1?
SN1 is an nucleophilic substitution rxn E1 is an elimination reaction Both of them are UNIMOLECULAR rxns, hence their name
30
What type of reactions are SN2 and E2?
Their are BIMOLECULAR rxns
31
What order of kinetics does SN1 and E1 follow?
First order kinetics
32
What order of kinetics do SN2 and E2 follow?
Second order kinetics
33
What kind of base is used for SN1/SN2 and E1/E2 rxns?
For SN1/E1, a WEAK BASE is used For SN2/E2, a STRONG BASE is used
34
What is Diel's Alder reaction?
Alkene + Conjugated diene --> Cyclohexene
35
What is Ozonolysis?
Alkene + O3 --in the presence of an inert compound like CCl4 --> OZONIDE --when treated with Zn--> produces CARBONYL COMPOUNDS LIKE ALDEHYDE OR KETONE
36
What is the colour given by Ceric Ammonium nitrite test in the presence of an alcohol?
Red colour
37
Victor Mayer test.
The alcohol is reacted with (I2 in RED P) Gives an ALKYL HALIDE (reacted with AgNO3) Gives NITROALKANE (treated with Nitrous acid) The resulting solution is made alkaline by adding CAUSTIC SODA
38
Which is the most commonly used test for distinguishing between 1°,2° and 3° alcohol?
Victor Mayer test
39
What are the colours of the resulting solution in Victor Mayer test?
For 1° alcohol - Red colour For 2° alcohol - Blue For 3° alcohol - No colour
40
What is Lucas Reagent?
ZnCl2 in HCl
41
Name a Polar aprotic solvent.
Di-methyl formamide (DMF)
42
What is Atropi-isomerism?
Isomers that can be interconverted by a single rotation
43
What is a Meso compound?
1. It is an Achiral compound that contains a chirality center 2. Contains a plane of symmetry 3. It is OPTICALLY INACTIVE
44
Why is CCl4 non-polar?
Because the compound is symmetrical
45
How is an IONIC bond formed?
It is formed between an anion and cation. It is mostly seen between metals and non-metals
46
How is a Hydrogen bond formed?
It is formed between a Hydrogen atom and an electronegative atom. It is a type of WEAK, COVALENT BOND
47
How is a Covalent bond formed?
It is formed by the sharing of an electron
48
What is the molecular mass of Glucose?
180 g/mol
49
Diel's Alder reaction is a type of ____ rxn.
It is a Cycloaddition rxn
50
Name some Pericyclic reactions.
Cycloaddition, Electrocyclic and Sigmatropic
51
What is a Sigmatropic reaction?
It is a type of reaction where a sigma bond rearranges itself due to the rearrangement of pi-electrons
52
Dipole moment is measured in. . .
Debye
53
How does Electronegativity inc/dec across the period table?
It INCREASES from (downward to up) It INCREASES from (left to right)