Childhood Diseases II Flashcards

(32 cards)

1
Q

What does gestational age refer to for full term, preterm, post-term, neonate, infant, and child?

A

Full Term - 38-42 weeks
Preterm - <38 weeks
Post-term - >42 weeks
Neonate - 0-28 days
Infant - 28 days - 1 year
Child - 1-17 years

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2
Q

What does the APGAR score test and what are normal scores?

A

Full score out of 10
Color - no cyanosis = 2
Heart rate - >100 = 2
Respiration - strong =2
Reflex - sneeze/cough or pulls away = 2
Muscle tone - active movement = 2

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3
Q

What does the APGAR score mean after 5 minutes?

A

0-1 score = 50% of death
4 = 20% death
>7 = 0% death

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4
Q

What does prematurity refer to?

A

Gestational age less than 38 weeks

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5
Q

What is the second cause of death in children less than 1 year old?

A

Prematurity

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6
Q

______ % of infants are born prematurely

A

12

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7
Q

What are signs of prematurity? x4

A

Small infant <2500 g
Thin skin
Reduced tone and activity
Extremities not flexed

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8
Q

What are the complications of prematurity? x5

A
  1. Hyaline membrane disease
  2. Necrotizing enterocolitis
  3. Sepsis
  4. Intraventricular hemorrhage
  5. Developmental decay
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9
Q

_______ is fetal weight that is below the 10th percentile for gestational age as determined through an ultrasound.

A

Fetal Growth Restriction

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10
Q

Fetal Growth Restriction is also called what other names?

A

Small for gestational age (SGA)

Intrauterine Growth Restriction (IUGR)

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11
Q

What are the 3 causes of Fetal growth restriction? Which one is the most common?

A
  1. Fetal abnormalities
  2. Placental abnormalities
  3. Maternal - the most common
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12
Q

Which cause of Fetal Growth Restriction is symmetric or asymmetric?

A

Fetal abnormalities - symmetric where all systems are similarly affected

Placental abnormalities - asymmetric

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13
Q

What occurs with baby of a smoking pregnant woman?

A

Prematurity

Fetal growth restriction - asymmetric with relative sparing of growth of brain and head relative to rest of body

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14
Q

What are the complications of Fetal Growth Restriction? x7

A
  1. Perinatal asphyxia
  2. Meconium aspiration
  3. Hypoglycemia
  4. Polycythemia
  5. Brain dysfunction
  6. Hearing and visual impairment
  7. Learning disability
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15
Q

What are birth injuries that can occur ?

A

Caput succedaneum
Subgaleal hematoma
Skull fractures
Intracranial hemorrhages
Brachial plexus, facial N injury
Other fractures, clavicle and humerus

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16
Q

What are 3 types of perinatal infections?

A
  1. Transplacental - hematogenous/descending
  2. Ascending (transcervical)
  3. Combined
17
Q

What are examples of transplacental infections? x5

A
  1. Toxoplasmosis
  2. Other - syphilis
  3. Rubella
  4. CMV infection
  5. Herpes virus infection
18
Q

What is the incidence and when does Congenital Rubella Syndrome occur?

A

20-90% incidence of subsequent fetal infection

Maternal rubella virus infection usually in 1st trimester

19
Q

What is congenital rubella syndrome characterized by?x5

A
  1. Low birth weight
  2. Purpuric rash
  3. Small head size - microcephaly
  4. Heart defects - PDA
  5. Visual problems - cataracts
20
Q

In pregnant syphilitic women, ________ occurs in 1/3. Of the fetus carried to term, 2/3 have __________

A

stillbirth

congenital syphilis

21
Q

Treponema pallidum ________ cross the placenta until the ______ of pregnancy, making prevention easy if mother receives prenatal care.

A

does not

5th month

22
Q

At birth, the infected infant’s skin and secretions with congenital syphilis are highly ______

23
Q

What are other physical characteristics of Congenital Syphilis?

A
  1. Hutchinson Incisors
  2. Mulberry molars
  3. Saber shin
24
Q

What pathogens cause ascending infections?

A

Bacterial - E.coli, GBS
Viral - herpes simplex II

25
What inflammations cause ascending infections?
Villitis Neonatal sepsis
26
What are the consequences of ascending infections?
Miscarriage Fetal growth restriction Preterm birth
27
What does perinatal ascending villitis present like under microscope?
Lymphocytic infiltrate of chorionic villi Associated with recurrent miscarriage and fetal growth restriction
28
What causes early onset neonatal sepsis? What is early onset considered?
Early onset = 0-7 days Gram + = Group B strep Gram - = E. coli and Klebsiella, leads to Pneumonia and Meningitis
29
What is considered late onset for neonatal sepsis?
8 days - 3 months
30
What are the risk factors of early onset neonatal sepsis? x5
1. Previous infant with GBS disease 2. GBS bacteriuria during pregnancy 3. Delivery before 37 weeks gestation 4. Ruptured membranes >18 h 5. Intrapartum temperature > 38 degrees celsius
31
How does neonatal pneumonia (ascending infection) present under microscope?
Many neutrophils filling bronchioles
32
How does pneumonia occur with ascending infection?
Fetus aspirated infected amniotic fluid into the lungs