Chlamydia Flashcards Preview

D1S U1 Microbiology > Chlamydia > Flashcards

Flashcards in Chlamydia Deck (15):
1

Small, gram-negative pathogen. No peptidoglycan in cell walls. Obligate intracellular pathogen. "Energy parasite"

Chlamydiae

2

Leading cause of preventable blindness. Most common agents of sexually transmitted bacterial infections. Causes "walking" pneumonia.

Chlamydial Infections

3

Chlamydial Infection spread by:

Droplet/direct contact. Infects mucosal epithelial cells. Localized (eyes, lungs, genitalia). Fingers, flies, fomites, fornication.

4

Causes Genital tract infections in both men and women, but usually asymptomatic in females. Infected infants get conjunctivitis and pneumonia.

C. Trachomatis infections

5

Transit form of C. Trachomatis. Enters epithelial cells (disguised as nutrients/growth factors/hormones), modifies endocytic vesicle, changes into larger intracellular active organisms (RB).

Elementary body (EB)

6

Chlamydial disease. STD. Systemic, invasive infection apparent in lymph nodes that drain genital tract.

Lymphogranuloma Venerum

7

Most prevalent chlamydial pathogen in human population. Usually asymptomatic or acute respiratory response. Can be directly observed in patients with atherosclerotic heart lesions.

Chlamydophila Pneumoniae

8

Chlamydophila Pneumoniae treatment:

Antimicrobials target metabolic active RB forms.

9

Small gram negative rods. Obligate intracellular bacteria. Zoonoses- infections transmitted from animals to humans. Capable of independent metabolism (not energy parasites)

Rickettsiae

10

Causes Rocky Mountain Spotted Fever. Reservoir in Ticks.

R. Rickettsii

11

Once inside blood, Rickettsiae attaches to ____ cells. And gets extruded from cells through ____

Vascular Endothelial cells (small blood vessels)

Filopodia

12

Obligate intracellular bacteria, transmitted by Lone Star tick. Infects monocytes/macrophages.

Ehrlichia

13

Diagnosis of Rickettsioses:

Problematic (usually too late for antibiotics)

14

Smallest organisms capable of growth on cell-free media. Requires sterol. Lack cell wall. Found in mammals/birds

Mycoplasma

15

Causes atypical (walking) pneumonia and hemolytic anemia. Humans only reservoir.

M. Pneumoniae