CHN II Flashcards
(337 cards)
Any microorganisms capable of producing a disease
e.g., bacteria, virus, fungi, parasites.
INFECTIOUS AGENT
Environment or object in which organism can survive or multiply
e.g., Human ,animals, fomites, soil, water
RESERVOIR
CHAIN OF INFECTION
Infectious Agent
Reservoir
Portal of Exit/ Mode of escape
Mode of Transmission
Portal of Entry
Susceptible Host
Venue or way which organism leaves the reservoir
Alimentary: Vomiting, diarrhea, biting
Respiratory: Coughing, sneezing, talking
Genitory-Urinary: Sexual - Transmission
Transplacental: Mother to Fetus
Skin:I Skin lesion, cut, blood
PORTAL OF EXIT/ MODE OF ESCAPE
Direct/Indirect Droplet
Particles: >5 mm
Distances: 3 feet
Contact
Respiratory secretions
Fine Particles: <5mm
More than 3ft distance
All droplets can be airborne (PTB)
Airborne
Carrier
e.g., Food, water, medication
Vehicle
Carrier
Insects; Mosquito
Vector
-Ingestion, Inhalation, Penetration
PORTAL OF ENTRY
-At risk -Infant & Children
-Old people -Immunocompromised
SUSCEPTIBLE HOST
-Entry until first s/sx
-Person is unaware of impending illness
INCUBATION PERIOD
-Nonspecific s/sx: Flu-like
-Activates immune response
PRODROMAL PERIOD
-Specific s/sx
-Pathognomonic sign
ACUTE PERIOD
-s/sx starts to disappear
-pt regains health
CONVALESCENT PERIOD
Healthy again.
RESOLUTION AGENT
-Physical & chemical barriers
-Natural flora
-Skin & mucuous membrane
-oils & sweats
-Cilia
-Gag, cough reflex
First line of Defense
-Inflammatory response
-Activate cells: B-E-N
Basophils, Eosinophils, Neutrophils
Second line of Defense
Redness; increase blood flow
Rubor
Swelling; Exudation of fluid
Tumor
Heat; Release of inflammatory Mediators
Calor
Pain; Stretching of pain receptors
dolor
Loss of function; Disruption of tissue structure
Functio Laesa
-Immune response (B-cells & T-cells)
-Specific Protection; Lymphocyres
THIRD LINE OF DEFENSE
-Proteins that destroy familiar antigen
ANTIBODIES