Cholinergic Agents Flashcards

0
Q

cevimeline (type)

A

muscarinic receptor agonist

selective for M3

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1
Q

pilocarpine (type)

A

muscarinic receptor agonist

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2
Q

pilocarpine use

A

glaucoma

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3
Q

methacholine type & side effect

A

muscarinic receptor agonist

bronchoconstriction

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4
Q

bethanechol type & side effect

A

muscarinic receptor agonist

urination

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5
Q

arecoline type & side effect

A

muscarinic receptor agonist

excessive sweating

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6
Q

muscarinic receptor agonist side effects (5)

A
sweating
GI motility
miosis
increased saliva
bronchoconstriction
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7
Q

varenicline type

A

partial nicotinic agonist

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8
Q

nicotinic agonist toxicity treatment

A

atropine

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9
Q

indirect cholinergic agonist mechanism of action

A

increased ACh time in the synaptic cleft

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10
Q

neostigmine type & use

A

cholinesterase inhibitor

myasthenia gravis tx

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11
Q

physostigmine type, treatment, and special characteristic

A

cholinesterase inhibitor
glaucoma tx
enters the CNS

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12
Q

edrophonium type & use

A

cholinesterase inhibitor

diagnosis of myasthenia gravis

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13
Q

organophosphate drugs

A

cholinesterase inhibitor, irreversible

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14
Q

Atropine drug type, use, characteristic

A

antimuscarinic
used in MI to decrease bradycardia
oral, enters CNS

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15
Q

atropine contraindications

A

glaucoma

BPH

16
Q

scopalomine drug type, use, characteristic

A

antimuscarinic
motion sickness, pre-anesthetic
enters CNS

17
Q

glycopyrrolate type and use

A

antimuscarinic

prevent vagal reflexes in surgery

18
Q

tropicamide type & use

A

antimuscarinic

induction of short-acting mydriasis

19
Q

homatropine type & effect

A

antimuscarinic

mydriasis

20
Q

ipratropium & tiotropium type, effect, and use

A

antimuscarinic
bronchodilation
asthma

21
Q

tolterodine, fesoterodine, darifenacin, solifenacin

type, special characteristic, & use

A

antimuscarinic
selective for M3
tx overactive bladder

22
Q

oxybutynin & trospium type & use

A

antimuscarinic

tx bladder spasm after prostate surgery

23
Q

antimuscarinic effects

A

dry mouth, decreased sweating, increased HR, blurred vision, mydriasis, urinary retention, hot/dry skin, bronchodilation, decreased GI motility

24
muscarinic antagonist contraindications (2)
narrow angle glaucoma | BPH
25
tx for muscarinic antagonist toxicity
cholinesterase inhibitor
26
antimuscarinic, selective for M3 (4)
tolterodine fesoterodine darifenacin solifenacin
27
antimuscarinics used to induce mydriasis (2)
tropicamide | homatropine
28
succinylcholine contraindications
soft tissue injury (burns, rhabdo, muscular dystrophy) | children under 8
29
succinylcholine type
depolarizing muscular blocker
30
tubocurarine type
non-depolarizing neuromuscular blocker
31
hexamethonium type
ganglion receptor blockers
32
mecamylamine type & characteristic
ganglion receptor blocker | enters CNS
33
ganglion receptor blocker effects (4)
mydriasis/loss of accommodation orthostatic hypotension tachycardia urinary retention