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Pharm II > Steroids > Flashcards

Flashcards in Steroids Deck (8)
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0
Q

steroid effects on carbs, proteins, and fats (3)

A

increases circulating levels of glucose, FFA, and amino acids
antagonizes insulin
redistribution of body fat

1
Q

Hydrocortisone (Cortef) properties

A

equal mineralocorticoid and glucocorticoid properties

2
Q

steroid CV effects (4)

A

increase vascular responsiveness to sympathetic stimulation
increased catecholamine effect
increased CV output (preload and stroke vol)
some Na+ and H2O retention (volume increase)

3
Q

steroid effects of endocrine (2)

A
decrease ACTH, GH, TSH, LH
increase PTH (osteoporosis) and epinephrine
4
Q

steroid immune effects (3)

A

immunosuppressive
blocks all steps in inflammation
suppression of wound healing

5
Q

glucocorticoid antagonist

A

Mifepristone (RU 486)

6
Q

mineralocorticoid antagonist

A

spironolactone

7
Q

corticosteroid synthesis inhibitors (2)

A

Aminoglutethimide

Ketoconazole