Chronic Kidney Disease Flashcards

(51 cards)

1
Q

you can have chronic kidney disease and normal renal function tests T or F

A

T

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2
Q

CKD tends to present without comorbidities T or F

A

F, usually presents with other conditions eg diabetes and CVD

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3
Q

the risk of developing CKD increases with age T or F

A

T

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4
Q

define CKD?

A

abnormal biochem or urinalysis for >90 days in >2 samples

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5
Q

eGFR has to be multiplied by ___ if you are afro-caribbean or african-american

A

1.2

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6
Q

a low stage of CKD would have a __ eGFR

A

normal/high

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7
Q

stage G1 CKD has an eGFR of

A

> 90

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8
Q

stage G5 CKD has an eGFR of

A

<15

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9
Q

what CKD stage should be referred to a renal specialist?

A

G4

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10
Q

what eGFR level would prompt starting dialysis?

A

<8

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11
Q

what does the A1 stage of albumin:creatinine ratio indicate?

A

no proteinuria

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12
Q

you should do an albumin:creatinine ratio if what is detected on testing?

A

proteinuria

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13
Q

you would have proteinuria if your A:C ratio was over…

A

3

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14
Q

what test should be used for AKI?

A

creatinine (not eGFR)

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15
Q

what test should be used for CKD?

A

eGFR

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16
Q

how long should be patients be montitored for after an episode of AKI and why?

A

2-3yrs; looking for signs of CKD

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17
Q

there is no relationship between past AKIs and increased risk of CKD: T or F

A

F, they are at a much higher risk and must be monitored

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18
Q

what conditions are monitored for CKD?

A

diabetes

hypertension

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19
Q

dysmorphic RBCs on urine microscopy indicate bleeding from where?

A

glomerulus

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20
Q

normal RBCs on urine microscopy indicate bleeding from where?

A

distal to glomerulus

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21
Q

when would CKD be defined as progression?

A

decreased eGFR by 25%

more proteinuria

22
Q

symptoms of CKD?

A
nocturia
dilute urine
tired
anorexia
itch
can't sleep
anaemia (dec. erythropoeitin)
23
Q

management of CKD?

A

control risk factors - salt reduction, smoking
ACEi to reduce BP and proteinuria (monitor eGFR)
atorvastatin 20mg
fluid restrict(1-1.5l) if overloaded
restrict phospate if PO4 high
active vit d + phosphate binders

24
Q

which patients with CKD should you refer?

A
G4 +
A3 (A:C ratio)
a decreasing eGFR (>25%)
difficult to control hypertension
suspect renal artery stenosis
25
when would you qualify with difficult to control hypertension?
using at least 4 hypertensive drugs at max dose
26
what BP target should a CKD patient aim for if they dont have proteinuria?
140/90mmHg
27
what BP target should you aim for in a CKD patient with proteinuria?
130/80mmHg
28
secondary causes of glomerulonephritis?
diabetes lupus heroin addiction obesity
29
vasculitic causes of CKD?
GPA MPA EGPA
30
what microangiopathies can cause CKD?
thrombotic thrombocytopaenia purpura | HUS
31
signs of advanced uraemia?
``` lemon yellow skin twitching encephalopathy- confusion/tremor peicardial rub metabolic acidosis - kussmauls ```
32
you are less likely to bleed when uraemic T or F
F, more likely
33
symptoms of uraemia?
``` nausea vomiting anorexia weight loss itch restless legs twitch altered taste ```
34
main categories of symptoms in CKD?
uraemia anaemia pain
35
type of pain felt in CKD?
neuropathic ischaemic bony visceral
36
symptoms of anaemia?
fatigue`
37
why do you get fluid overload and hypertension in CKD?
impaired salt and water handling
38
why do you get nocturia in CKD?
can't concentrate urine so will need to pee constantly
39
why do you get metabolic acidosis in CKD?
impaired reabsorption and secretion of H+ and HCO3
40
what can CKD cause?
bone disease CVD anaemia
41
Tx of end stage renal failure?
haemodialysis peritoneal dialysis (draws off salt + h20) transplant conservative
42
how much higher is mortality of CVD in dialysis patients compared to non-renal patients?
10-20x higher
43
best form of vascular access for dialysis?
arteriovenous fistula
44
what form of hyperparathyroidism can happen as a result of CKD and why?
tertiary as you get hyperplasia of glands -> hypercalcaemia
45
should you be able to see BVs on x ray?
no, can only see them if they're calcified
46
what is calciphylaxis?
calcification and occlusion of the medium sized blood vessels
47
what patient would not fall into the increased risk category for CKD? 1. diabetic 2. hypertension pt 3. coronary heart disease pt 4. long term steroid pt 5. pt with family history of stage 3 ckd
FH of CKD | only worry if someone in the family had stage 5
48
chronic __ disease is a risk factor for urinary incontinence?
lung
49
which GFR is stage 4 CKD?
15-29
50
first line therapy for high BP in a patient with CKD and proteinuria
ACEi
51
how would a patient with stage 3 CKD be monitored
measure eGFR, PCR, Hb, K, Ca and phosphate 6 monthly