Prostate and Bladder Cancer Flashcards

1
Q

where is the prostate located?

A

neck of the bladder

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2
Q

how much doe the prostate weigh in a young male?

A

around 20g

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3
Q

the prostatic urethra is covered by what epithelium?

A

transitional

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4
Q

how many zones does the prostate have?

A

5 (3 main)
transitional zone
central zone
peripheral zone

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5
Q

BPH arises in what zone of the prostate?

A

transitional zone

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6
Q

prostate adenocarcinoma arises in what zone of the prostate?

A

peripheral

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7
Q

what zone of the prostate surrounds the ejaculatory ducts?

A

central

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8
Q

what zone of the prostate surrounds the prostatic urethra?

A

transitional

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9
Q

what is the incidence and prevalence of prostate cancer?

A
incidence = low
prevalence = high
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10
Q

where are the seminal vesicles located?

A

prostate

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11
Q

how is prostate cancer diagnosed?

A

PSA (prostate specific antigen)
PR exam
TRUS biopsy to confirm diagnosis
Gleason score to confirm prognosis

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12
Q

what releases PSA?

A

prostate gland

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13
Q

prostate cancer arises from what zone?

A

peripheral

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14
Q

which zone is nearest the rectum?

A

peripheral

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15
Q

what other conditions elevate the PSA?

A
BPH
prostatitis
UTI
retention
catheterisation
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16
Q

prostate cancer prognosis is graded using which system?

A

gleason’s scoring

17
Q

most common prostate cancer?

A

adenocarcinoma

18
Q

where does prostate cancer metastasise to?

A

pelvic lymph nodes

bone

19
Q

main imaging used for staging prostate cancer?

A

bone scan

MRI scan

20
Q

what PSA would indicate high risk prostate caner?

A

> 20

21
Q

Tx for low risk?

A

monitor and treat symptomatically
surgery
radiotherapy + hormone therapy

22
Q

Ix for bladder cancer?

A

CT urogram

flexible cystoscopy

23
Q

what hormonal therapy is used in metastatic prostate cancer?

A

androgen deprivation therapy

24
Q

Tx for organ confined prostate cancer?

A

surgery
radiotherapy
watchful waiting

25
Q

what hormones control growth of prostate cancer cells?

A

testosterone

dihydrotestosterone