Microbiology of UTI Flashcards

(37 cards)

1
Q

the lower end of the urethra is colonised by what 2 main types of bacteria?

A

coliforms

enterococci

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2
Q

complicated UTI is a UTI complicated by..

A

systemic symptoms
structural abnormality
stones

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3
Q

most common route of infection?

A

ascending from bowel -> urethra up to kidneys potentially

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4
Q

what bacteria can travel in the bloodstream to cause a UTI?

A

staph aureus

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5
Q

most common UTI bug?

A

e coli

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6
Q

how does e coli stay in the urinary tract?

A

fimbriae which help it cling to surfaces

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7
Q

urinalysis is mainly only used for ruling out infection in UTI T or F

A

T, you want a culture to confirm infection

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8
Q

what are you expecting to see on microscope in a common UTI?

A

gram negative bacilli (E coli)

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9
Q

lipopolysaccarides live in gram _ve cell walls

A

negative

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10
Q

which coliform bacteria causes stones?

A

proteus

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11
Q

“swarming cultures” are a sign that ___ has grown

A

proteus

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12
Q

what does proteus smell of?

A

burnt chocolate

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13
Q

how does proteus cause stones?

A

produces urease which increases pH

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14
Q

which non-coliform can cause UTIs?

A

pseudomonas aeruginosa

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15
Q

pseudomonas is resistant to most oral antibiotics except ___

A

ciprofloxacin

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16
Q

what does ciprofloxacin inhibit?

17
Q

most common gram +ve cause of UTI?

A

enterococcus faecalis

18
Q

what 2 types of bacteria cause an upper UTI?

A

coliforms

gram +ves (e. faecalis mainly)

19
Q

staph saphrophyticus can be found in who?

A

women of child bearing age

20
Q

symptoms of UTI?

A

dysuria
frequency
nocturia
haematuria

21
Q

what symptoms make you think upper UTI?

A

fever
loin pain
rigors

22
Q

how should urine be collected in UTI?

A
get a mid stream sample:
wash urethra with saline
pee into toilet
pee into bowl mid pee
finish pee in toilet
23
Q

what colour container is used to collect urine in the community

24
Q

urine can only be collected in a white container if it reaches the lab within _ hrs

25
nitrites confirm the presence of what bacteria?
coliforms
26
who shouldnt get urinalysis?
elderly | people with catheters
27
main Ix for UTI?
urine culture
28
UTI is caused by a single organism T or F
T
29
Tx for female uncomplicated UTI?
trimethoprim 3 days
30
Tx for male uncomplicated UTI?
trimethoprim or nitrofurantoin 7 days
31
Tx for complicated UTI in primary care?
co-trimoxazole or co-amoxiclav 7 days
32
Tx for complicated UTI in hosp?
amoxicillin + gentamicin IV 7 days
33
Tx for complicated UTI in hosp (pen allergic)
co-trimoxazole PO + gentamicin IV 3 days
34
gentamicin has a __ therapeutic index making it likely to become toxin
narrow
35
what drug should be used for ESBL bacteria?
meropenem
36
what should be used 2nd line if the patient has renal problems and cant have gentamicin?
aztreonam
37
why cant pregnant women use trimethoprim in the 1st trimester?
inhibits folic acid synthesis