Renal, Penile and Testicular Cancer Flashcards

(48 cards)

1
Q

what mnemonic should be used when learning the pathology of a disease

A

in a surgeon’s gown a physician may make some progress

incidence
age
sex
geographic
aetiology
predisposing factors
macroscopic appearance
microscopic appearance
spread
prognosis
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2
Q

what type of cancer affects the renal pelvis?

A

transition cell carcinoma

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3
Q

what imaging is best to differentiate a cyst from a solid mass?

A

USS

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4
Q

what imaging is best to differentiate a tumour from a haemorrhage?

A

MRI

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5
Q

Ix for benign renal cysts?

A

USS

contrast CT if concerned

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6
Q

Ix of angiomyolipoma?

A

CT

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7
Q

main complication of angiomyolipoma?

A

haemorrhage

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8
Q

an oncocytoma is a benign cancer T or F

A

T

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9
Q

what tumour presents with a central scar on CT?

A

oncocytoma

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10
Q

which benign renal tumour is the hardest to diagnose?

A

oncocytoma

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11
Q

classic triad of renal cell carcinoma?

A

loin pain
mass
haematuria

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12
Q

what paraneoplastic symptoms will patients with RCC present with?

A

weight loss
anaemia
hypertension
hypercalcaemia

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13
Q

why do patients with RCC present with loin pain?

A

necrosis of fat

bleeding into collecting system (clots in ureter)

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14
Q

why do you get hypercalcaemia in RCC?

A

make parathyroid peptide as these tumours are VERY metabolically active

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15
Q

RCC is a tumour of the ___

A

epithelium

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16
Q

young patient presents with multiple cysts and benign tumours….

A

von hippel lindau

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17
Q

inheritance of VHL?

A

autosomal dominant

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18
Q

if a young person presents with bilateral RCC what are they likely to have as well?

A

von hippel lindau syndrome

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19
Q

Ix of RCC?

A

USS
CT contrast
renal biopsy

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20
Q

Tx of RCC?

A

radical nephrectomy (adrenals spared)
partial nephrectomy
ablation

21
Q

should you take out the adrenal gland in a nephrectomy?

22
Q

main aim of a partial nephrectomy?

A

spare the nephron

23
Q

a small renal mass is under _cm

24
Q

Ix for a small renal mass?

A

renal biopsy - benign/malignant

25
what is BXO?
balanitis xerotica obliterans (white scarring of the foreskin)
26
presentation of BXO?
white patches fissuring bleeding scarring
27
Tx of BXO?
dilation of meatal stenosis circumcision glans resurfacing
28
most common carcinoma in situ of penis?
squamous
29
appearance of squamous carcinoma in situ of penis?
erythroplasia of glans, prepuse or shaft | red velvety patces
30
Tx of squamous carcinoma in situ?
circumcision | topical 5-fluorocil
31
presentation of carcinoma of penis?
red raised area on penis fungating mass foul smelling phimosis
32
what age is most commonly affected by penile carcinoma?
80yrs
33
cause of penile carcinoma?
HPV type 16
34
Ix of penile carcinoma?
biopsy USS physical examination
35
Tx of carcinoma of penis?
surgery- total/partial penectomy LN biopsy if spread radiotherapy
36
what lymph nodes can a penile carcinoma spread to?
inguinal lymph nodes
37
carcinoma of the penis is a squamous cell carcinoma T or F
T
38
testicular tumours are extremely painful T or F
F, painless and insensitive
39
where do testicular tumours metastasise to?
neck nodes | dyspnoea
40
gold standard Ix for testicular tumour?
USS
41
what investigations should be done to stage a testicular tumour?
CT abdo/thorax | CXR
42
give example of a testicular tumour?
seminoma | teratoma
43
HCG is raised in what testicular tumour?
teratoma mainly
44
what markers should be tested in a testicular tumour?
AFP HCG LDH
45
Tx of testicular tumour?
orchidectomy of testicle
46
peak age for a testicular tumour?
20-35yrs
47
risk is much greater if you had an undescended testis as a child T orF
T
48
what type of teratoma always has an elevated HCG level?
trophoblastic