CHUNG AND NAYA (2000)- ffectiveness of Electrically Measuring Adherence and compliance

Question 1

What was the aim of Chung and Naya (2000) study?

Answer 1

To investigate the effectiveness of electronically measuring medication adherence and compliance in asthma patients using a TrackCap.

Question 2

How was adherence operationalised in this study?

Answer 2

(% of days in which both tablets were taken approx. 12 hours a part as instructed)

Question 3

How was compliance operationalised in the study?

Answer 3

% of days in which correct medication dosage/ amount is taken

the correct medication is taken but not exactly 12 hours a part as instructed

Question 4

What medication were the ppts taking?

Answer 4

Zafirlukast (oral medication for asthma)

Question 5

What method did Chung and Naya (2000) use?

Answer 5

• Clinical trial- but in a naturalistic setting (patients took medication at home)
• Longitudinal (12 week trial)

Question 6

What was the duration of the clinical trial?

Answer 6

12 weeks

Question 7

What is a MEMS device?

Answer 7

A device that records the time and date of every time the medicine cap is removed and replaced (TrackCap was the brand used in the study).

Question 8

How much ppts were in the sample?

Answer 8

57 asthma patients

Question 9

Summarise the procedure?

Answer 9

1. Medication distribution
2. Supervision and physical asssessents
3. Adherence rates assessed

Question 10

Explain the procedure of Chung and Naya (2000) study?

Answer 10

1. Medication- ppts were given 3 weeks of Zafirlukast and were instructed to take 1 tablet in the morning and 1 in the evening (approx 12 hours a part). Patients were told their compliance was being measured, but they were not told how it would be measured.
2. Supervision- ppts attended the clinic every 3 weeks for a physical assessment. They were instructed to return any unused tablets and have the bottle replaced for another 3 weeks supply.
3. Measuring adherence- adherence was assessed based on 4 classifications

Question 11

What 4 classifications was used to measure adherence and compliance?

Answer 11

• Insufficient interval adherence: Days in which medication was taken twice, with less than 8 hours between both times.
• Undercompliance: Days in which medication was only taken once (one event)
• No compliance: Days in which NO medication was taken.
• Over-compliance: Days in which medication was taken more than the recommended 2 times.