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Flashcards in CIS Deck (12)
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1

What can point towards AKI

-decreased GFR (increased plasma creatinine >0.3 mg/dL in 48h)
-increase in serum creatinine to 1.5x baseline
-urine volume <0.5 mL/kg/hr for 6 hours

2

What score do we associate with moderated decreased GFR

Stage 3

30-59 moderately decreased

3

What is high urine sodium associated with

AKI, drugs, renal disease

4

What is low urine sodium associated with

Hypovolemia, nephrosis, cirrhosis, CHF, drugs

5

When is urine K high

Vomiting, diarrhea, drugs

6

When is urine K low

Renal disease with hormone implications

7

What are the causes of acute tubular necrosis

85% of cases

Common: hypotension and sepsis

Other: renal ischemia, nephrotoxins, major surgery, hypoperfusion, endogenous toxins, burns

8

What are the symptoms associated with acute glomerulonephritis

Hematuria and proteinuria

9

What are the causes of acute glomerulonephritis

Hypertension, edema, hypoercoagulability

10

What are the proportions of AKI and what are they

85% acute tubular necrosis
10% interstitial nephritis
5% acute glomerulonephritis

11

What are the symptoms of acute interstitial nephritis

Decline in renal function secondary to lesion

12

What causes acute interstitial nephritis

Inflammatory reaction within the renal interstitium

Induced by:
-drug therapy (commonly antibiotics)
-autoimmune disorders (lupus and scleroderma)
-infections (streptococcal and legionella)