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Renal Midterm > Elements of Renal Function > Flashcards

Flashcards in Elements of Renal Function Deck (63)
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1

what are some waste products that the kidneys remove

urea, creatinine, acid, bilirubin, other stuff

2

where is EPO made

kidneys

3

what is EPO made in response to

low PO2

4

what causes drops in PO2

anemia caused by blood loss, arterial hypoxia, inadequate renal flow

5

what is calcitriol and where is it made

active Vit D; kidneys

6

where does gluconeogenesis occur

mostly liver but a substantial amount can happen in kidneys

7

the cortex contains what

renal corpuscles, coiled blood vessels, and coiled tubules

8

the medulla contains

straight blood vessels and straight tubules

9

the microcirculation of the kidneys is comprised of how many capillary networks and how are they arranged

2; in series

10

what are the capillaries of the kidney

glomerular and peritubular

11

what does the glomerular capsule prefer

filtration

12

what does the peritubular capillary prefer

absorption

13

what are the Pc of the glomerular and peritubular capillaries

~60 mm Hg; ~13 mm Hg

14

long medullary peritubular capillaries are often called

vasa recta

15

where is renal blood flow highest

cortex then outer medulla then inner medulla

16

when do we start losing nephrons

10% each decade beyond 40

17

what is the main process of the glomerulus

filtration via starling forces

18

what is the main process of the proximal tubule

reabsorption of the largest fraction of glomerular filtrate

19

what is the main process of the loop of henle

controlling urine concentration and secreting Tamm-Horsfall glycoproteins

20

what is the main process of the distal tubule/collecting ducts

fine control of salt and water secretion

21

How do you calculate renal clearance C_x

C_x=Urine concentration of X * urine volume/ concentration of X in plasma

22

How do you calculate glomerular flow rate

GFR = urine concentration of inulin*urine volume/plasma concentration of inulin

23

How do calculate clearance ratio

Clearance of X / clearance of inulin

24

How do you calculate renal plasma flow

RPF = (urine concentration of PAH * urine volume)/ (renal artery PAH concentration - renal vein concentration of PAH)

25

What is the issue with effective renal plasma flow

Underestimates RPF by 10%

26

What is effective renal plasma flow also equal to

Clearance of PAH

27

How do you calculate the Glomerular Filtration Rate

GFR = urine concentration of inulin * urine volume / plasma concentration of inulin

28

What does glomerular filtration rate also equal

Clearance of inulin

29

How do you calculate filtration fraction

FF - GFR / RPF

30

How do you calculate filtered load

Filtered load = GFR * plasma concentration of X