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Flashcards in CK Deck (111)
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1

skin cancer - types and MC

1. basal cell carcinoma (BCC) (MC)
2. Squamous cell carcinoma
3. Melanoma

2

basal cell carcinoma (BCC) of the skin is found in (area of the body and classic location) / behavior

sun exposed areas / classic location: upper lip
1. locally invasive
2. RARELY metastasizes

3

basal cell carcinoma (BCC) of the skin - macroscopic appearance

- PINK, pearly nobules, commonly with telengectasias, rolled borders, central crusting or ulceration
- nonhealing ulcer with infiltrating growth or as a scaling plaque (superficial BCC)

4

basal cell carcinoma (BCC) of the skin - Histology

clusters of darkly staining basaloid cells with a palisade

5

Squamous cells carcinoma (SCC) of the skin is associated with (risk factors)

1. excessive exposure to sunlight
2. immunosuppression
3. arsenic exposure

6

Squamous cells carcinoma (SCC) of the skin commonly appears on

1. face 2. lower lip 3. ears 4. hands

7

Squamous cells carcinoma (SCC) of the skin - behavioural

- locally invasive
- may spread to lymph nodes
- metastasize: uncommon

8

Squamous cells carcinoma (SCC) of the skin - macroscopic appearance / associated with

ulcerative red lesions with frequent scale.
- chronic drainage sinus

9

Squamous cells carcinoma (SCC) of the skin - precursor lesion and appearance

Actinic keratosis
scaly plaque, hyperkeratotic
(small, rough, erythematous or brownish papules or plaques)

10

keratoacanthoma - definition

keratoacanthoma is a variant (well differentiated squamous cell carcinoma that develops rapidly (4-6 weeks) and may regress spontaneously over months

11

keratoacanthoma - present as a

cap-shaped tumor filled with keratin debris

12

melanoma - risk factors

1. sunlight exposure
2. fair-skinned persons are at high risk

13

melanoma - some subtypes (MC?)

1. superficial spreading (MC)
2. nodular
3. lentigo maligna
4. acral lentiginous

14

superficial spreading melanoma - growth / prognosis

radial
good prognosis

15

lentigo maligna melanoma - prognosis / growth

good prognosis
radial growth

16

nodular melanoma - growth / prognosis

early vertical
poor prognosis

17

acral lentiginous melanoma - special feature

it is not related with UV light exposure
PALMS AND SOLES

18

Basal vs squamous cell carcinoma according area of the lips

SCC -> lower lip
BCC --> upper lip

19

skin layers:

1. epidermis
2. dermis
3. subcutaneous fat (hypodermis or subcutis )

20

epidermis layers - from surface to base (only the names)

1. stratum corneum
2. stratum lucidum
3. stratum granulosum
4. stratum spinosum
5. statum basale

21

hyperkeratosis - definition + example

increased thickness of stratum corneum
psoriasis / calluses

22

parakeratosis - definition / examplie

hyperkeratosis with retention of nuclei in stratum corneum
psoriasis

23

spongiosis - definition / example

epidermal accumulation of edematous fluid in inter-cellular spaces
eczematous dermatitis

24

acantholysis - definition
hypergranoulosis - definition

acantholysis: seperation of epidermal cells
hypergranoulosis: increased thickness of stratum granulosum

25

acantholysis example
hypergranoulosis - example

acantholysis: pemphigus vulgaris
hypergranoulosis: liches planus

26

acanthosis - definition

epidermal hyperplasia (increased spinosum)

27

patch - definition

flat lesion with well-circumscribed change in skin color, more than 1 cm (macule but more than 1cm)

28

macule -definition

flat lesion with well-circumscribed change in skin color less than 1 cm

29

papule - definition

elevated solid skin lesion

30

plaque - definition

elevated solid skin lesion more than 1cm (papule but more than 1cm)