histology and terminology of skin/epitelial cell junction/pigmented skin disorders Flashcards Preview

dermatology > histology and terminology of skin/epitelial cell junction/pigmented skin disorders > Flashcards

Flashcards in histology and terminology of skin/epitelial cell junction/pigmented skin disorders Deck (87)
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1

skin has ... (number) layers

3

2

skin layers:

1. epidermis
2. dermis
3. subcutaneous fat (hypodermis or subcutis )

3

subcutaneous fat of skin is also called 3

hypodermis or subcutis

4

epidermis layers - from surface to base (only the names)

1. stratum corneum
2. stratum lucidum
3. stratum granulosum
4. stratum spinosum
5. statum basale

5

epidermis layers - statum corneum is characterised by

keratin in anucleated cells

6

epidermis layers - stratum lucidum is characterised by

dead skin cells

7

epidermis layers - stratum granulosum is characterised by

granules in keratinocytes

8

epidermis layers - stratum spinosum is characterised by

desmosomes between keratinocytes

9

epidermis layers - stratum basale is characterised by

stem cells

10

skin function

barrier against environmental insults and fluid loss

11

dermis is seperated by epidermis by

basement membrane

12

dermis consists of

connective tissue, nerve ending, blood and lymphocyte vessels, adnexal structures

13

dermis - adnexal structures

hair shafts, sweat glands, sebacous glands

14

adnexal structures in greek

εξαρτηματικές δομές

15

epidermis layers - desmosomes between keratinocytes

stratum spinosum

16

epidermis layers - granules in keratinocytes

stratum granulosum

17

epidermis layers - dead skin cells

stratum lucidum

18

hyperkeratosis - definition

increased thickness of stratum corneum

19

examples of hyperkeratosis

1. psoriasis
2. calluses

20

parakeratosis - definition

hyperkeratosis with retention of nuclei in stratum corneum

21

parakeratosis - example

psoriasis

22

spongiosis - definition

epidermal accumulation of edematous fluid in inter-cellular spaces

23

spongiosis - example

eczematous dermatitis

24

acantholysis - definition
hypergranoulosis - definition

acantholysis: seperation of epidermal cells
hypergranoulosis: increased thickness of stratum granulosum

25

acantholysis example
hypergranoulosis - example

acantholysis: pemphigus vulgaris
hypergranoulosis: liches planus

26

acanthosis - definition

epidermal hyperplasia (increased spinosum)

27

acanthosis - example

acanthosis nigricans

28

patch - definition

flat lesion with well-circumscribed change in skin color, >1 cm (macule but >1cm)

29

macule -definition

flat lesion with well-circumscribed change in skin color less than 1 cm

30

patch example

large birthmark (congenital nevus)